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• W2096358462 startingPage "46" @default.
• W2096358462 abstract "A series of experiments was carried out in which genetically female Nile tilapia (Oreochromis niloticus) fry were treated with Fadrozole, a nonsteroidal aromatase inhibitor (AI), in the diet during the period of sexual differentiation. Batches of tilapia fry treated with AI during the first 30 days following yolk-sac resorption (7–37 days post hatch, dph) showed a dose-dependent increase in the percentage of males from 0 to 200 mg · kg–1. The percentage of males remained approximately constant (92.5–96.0%) from 200 to 500 mg · kg–1. Any continuous 2- or 3-week treatment with 500 mg · kg–1 AI in this 4-week period successfully masculinized the majority of the treated fish (>80%). Treatments of 1 week duration revealed that the most sensitive time to AI lies in the first week (between 7 and 14 dph). Progeny testing of males from AI-treated groups gave results indicating that these were XX males, as expected. These experiments strongly implicate aromatase activity as a key factor in sexual differentiation in the Nile tilapia. J. Exp. Zool. 287:46–53, 2000. © 2000 Wiley-Liss, Inc." @default.
• W2096358462 created "2016-06-24" @default.
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• W2096358462 date "2000-01-01" @default.
• W2096358462 modified "2023-10-05" @default.
• W2096358462 title "Masculinization of genetic female Nile tilapia (Oreochromis niloticus) by dietary administration of an aromatase inhibitor during sexual differentiation" @default.
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• W2096358462 doi "https://doi.org/10.1002/1097-010x(20000615)287:1<46::aid-jez6>3.0.co;2-x" @default.
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