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- W2096429558 abstract "AbstractThe effect of single direct compression vehicles or their binary blends on some physical properties of thiamine hydrochloride tablets was Investigated. The pure drug has very poor flow and compression characteristics. It needed not less than 79% w/w of a direct compression vehicle to yield a flowable compressible mix* Tablets of high physical standards were produced with single vehicles such as Avicel PH 101, Celutab and Anhydrous lactose, USP respectively. On the contrary, neither STAR-x nor 'Decompress could be used to produce thiamine hydrochloride tablets with good physical characteristics. The tabletting property of each of the unsatisfactory vehicle was improved by blending with a vehicle that has good tabletting property. An exponential relationship between hardness and friability of the compressed tablets was derived. There was no direct relationship between the hardness and disintegration of the tablets." @default.
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- W2096429558 date "1988-01-01" @default.
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- W2096429558 title "Some Physical Properties of Directly Compressed Thiamine Hydrochloride Tablets" @default.
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- W2096429558 doi "https://doi.org/10.3109/03639048809151880" @default.
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