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• W2096431129 abstract "Using a radioimmunoassay technique serum alpha-fetoprotein could be detected in healthy adults in concentrations of less than 20 microgram/l. Of patients with acute, viral hepatitis 43% exhibited a transient rise of serum alpha-fetoprotein, the peak occurring eight to nine days after the maximum recorded serum aspartate transaminase activity. Patients with hepatic damage due to paracetamol poisoning were also shown to have transiently raised levels, the peak occurring earlier than in subjects with viral hepatitis. Six subjects with fatal fulminant hepatitis were studied; the three with the more protracted illness were noted to have increased levels before death. Twenty of 163 cases of chronic liver disease also had raised serum alpha-fetoprotein concentrations. In four, primary liver cell cancer developed; in two of these the serum alpha-fetoprotein levels rose progressively, and in two it remained raised but at low levels." @default.
• W2096431129 created "2016-06-24" @default.
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• W2096431129 date "1977-08-01" @default.
• W2096431129 modified "2023-10-03" @default.
• W2096431129 title "Serum alpha-fetoprotein levels in patients with acute and chronic liver disease. Relation to hepatocellular regeneration and development of primary liver cell carcinoma." @default.
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• W2096431129 doi "https://doi.org/10.1136/jcp.30.8.704" @default.
• W2096431129 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/476528" @default.
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