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- W2096474417 endingPage "a017780" @default.
- W2096474417 startingPage "a017780" @default.
- W2096474417 abstract "Position-effect variegation (PEV) results when a gene normally in euchromatin is juxtaposed with heterochromatin by rearrangement or transposition. When heterochromatin packaging spreads across the heterochromatin/euchromatin border, it causes transcriptional silencing in a stochastic pattern. PEV is intensely studied in Drosophila using the white gene. Screens for dominant mutations that suppress or enhance white variegation have identified many conserved epigenetic factors, including the histone H3 lysine 9 methyltransferase SU(VAR)3-9. Heterochromatin protein HP1a binds H3K9me2/3 and interacts with SU(VAR)3-9, creating a core memory system. Genetic, molecular, and biochemical analysis of PEV in Drosophila has contributed many key findings concerning establishment and maintenance of heterochromatin with concomitant gene silencing." @default.
- W2096474417 created "2016-06-24" @default.
- W2096474417 creator A5018351542 @default.
- W2096474417 creator A5086056549 @default.
- W2096474417 date "2013-08-01" @default.
- W2096474417 modified "2023-10-18" @default.
- W2096474417 title "Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila" @default.
- W2096474417 cites W104588731 @default.
- W2096474417 cites W122629173 @default.
- W2096474417 cites W1530362142 @default.
- W2096474417 cites W1550152339 @default.
- W2096474417 cites W1575147957 @default.
- W2096474417 cites W158710173 @default.
- W2096474417 cites W1594824935 @default.
- W2096474417 cites W1770558510 @default.
- W2096474417 cites W1832574878 @default.
- W2096474417 cites W1846174347 @default.
- W2096474417 cites W1856601345 @default.
- W2096474417 cites W1875039306 @default.
- W2096474417 cites W1928111150 @default.
- W2096474417 cites W1933321168 @default.
- W2096474417 cites W1939654294 @default.
- W2096474417 cites W1943142958 @default.
- W2096474417 cites W1963657604 @default.
- W2096474417 cites W1964762506 @default.
- W2096474417 cites W1968048723 @default.
- W2096474417 cites W1974141543 @default.
- W2096474417 cites W1978395898 @default.
- W2096474417 cites W1982461647 @default.
- W2096474417 cites W1986156899 @default.
- W2096474417 cites W1987687886 @default.
- W2096474417 cites W1989128392 @default.
- W2096474417 cites W1996287615 @default.
- W2096474417 cites W1997364279 @default.
- W2096474417 cites W1998819363 @default.
- W2096474417 cites W2003250545 @default.
- W2096474417 cites W2003981507 @default.
- W2096474417 cites W2006149421 @default.
- W2096474417 cites W2007030194 @default.
- W2096474417 cites W2010126413 @default.
- W2096474417 cites W2010212179 @default.
- W2096474417 cites W2015244743 @default.
- W2096474417 cites W2015595212 @default.
- W2096474417 cites W2017026491 @default.
- W2096474417 cites W2018231802 @default.
- W2096474417 cites W2018420071 @default.
- W2096474417 cites W2021194721 @default.
- W2096474417 cites W2022200034 @default.
- W2096474417 cites W2023771701 @default.
- W2096474417 cites W2024661042 @default.
- W2096474417 cites W2025537241 @default.
- W2096474417 cites W2027490859 @default.
- W2096474417 cites W2029493849 @default.
- W2096474417 cites W2033828311 @default.
- W2096474417 cites W2034161629 @default.
- W2096474417 cites W2034957983 @default.
- W2096474417 cites W2035726721 @default.
- W2096474417 cites W2037589637 @default.
- W2096474417 cites W2039623374 @default.
- W2096474417 cites W2052917514 @default.
- W2096474417 cites W2053291659 @default.
- W2096474417 cites W2054858743 @default.
- W2096474417 cites W2057185906 @default.
- W2096474417 cites W2064025098 @default.
- W2096474417 cites W2066018141 @default.
- W2096474417 cites W2067564842 @default.
- W2096474417 cites W2076438782 @default.
- W2096474417 cites W2084940129 @default.
- W2096474417 cites W2087558654 @default.
- W2096474417 cites W2093189184 @default.
- W2096474417 cites W2096891351 @default.
- W2096474417 cites W2101092089 @default.
- W2096474417 cites W2102898261 @default.
- W2096474417 cites W2105624980 @default.
- W2096474417 cites W2106900737 @default.
- W2096474417 cites W2111161390 @default.
- W2096474417 cites W2111271958 @default.
- W2096474417 cites W2117443539 @default.
- W2096474417 cites W2117616460 @default.
- W2096474417 cites W2118240383 @default.
- W2096474417 cites W2121417064 @default.
- W2096474417 cites W2123051193 @default.
- W2096474417 cites W2126094650 @default.
- W2096474417 cites W2126117869 @default.
- W2096474417 cites W2126522307 @default.
- W2096474417 cites W2126615487 @default.
- W2096474417 cites W2127843746 @default.
- W2096474417 cites W2129679422 @default.
- W2096474417 cites W2133736195 @default.
- W2096474417 cites W2134002573 @default.
- W2096474417 cites W2134400717 @default.
- W2096474417 cites W2136302838 @default.
- W2096474417 cites W2136314703 @default.
- W2096474417 cites W2137493363 @default.
- W2096474417 cites W2138043022 @default.
- W2096474417 cites W2138241268 @default.
- W2096474417 cites W2139220897 @default.
- W2096474417 cites W2140244319 @default.