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- W2096479368 abstract "The macrolide antibiotic erythromycin is produced by different genera of the Actinomycetales, including strains of Saccharopolyspora, Arthrobacter, Micromonospora and possibly Streptomyces. Erythromycin is also produced by several unclassified strains, four of which could be assigned to the genus Saccharopolyspora on the basis of bacteriophage host specificity. We used cloned erythromycin biosynthetic and resistance genes from Saccharopolyspora erythraea as hybridization probes to determine if the DNA sequences encoding these genes are conserved in different genera. Our results indicated strong hybridization to genomic restriction fragments from strains that were assigned to the genus Saccharopolyspora, and weak hybridization to DNA from strains which produce erythromycin or other macrolides but belong to other genera." @default.
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- W2096479368 date "1990-09-01" @default.
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- W2096479368 title "DNA homology between Saccharopolyspora strains and other erythromycin-producing actinomycetes" @default.
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- W2096479368 doi "https://doi.org/10.1099/00221287-136-9-1899" @default.
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