FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096501414> ?p ?o ?g. }

• W2096501414 endingPage "190" @default.
• W2096501414 startingPage "176" @default.
• W2096501414 abstract "Gene gun is a micro-particles delivery system which accelerates DNA loaded micro-particles to a high speed so as to enable penetration of the micro-particles into deeper tissues to achieve gene transfection. Previously, microneedle (MN) assisted micro-particles delivery has been shown to achieve the purpose of enhanced penetration depth of micro-particles based on a set of laboratory experiments. In order to further understand the penetration process of micro-particles, a mathematical model for MN assisted micro-particles delivery is developed. The model mimics the acceleration, separation and deceleration stages of the operation of a gene gun (or experimental rig) aimed at delivering the micro-particles into tissues. The developed model is used to simulate the particle velocity and the trajectories of micro-particles while they penetrate into the target. The model mimics the deceleration stage to predict the linear trajectories of the micro-particles which randomly select the initial positions in the deceleration stage and enter into the target. The penetration depths of the micro-particles are analyzed in relation to a number of parameters, e.g., operating pressure, particle size, and MNs length. Results are validated with experimental results obtained from the previous work. The results also show that the particle penetration depth is increased from an increase of operating pressure, particle size and MN length. The presence of the pierced holes causes a surge in penetration distance." @default.
• W2096501414 created "2016-06-24" @default.
• W2096501414 creator A5011151754 @default.
• W2096501414 creator A5018003703 @default.
• W2096501414 creator A5046274300 @default.
• W2096501414 date "2015-03-01" @default.
• W2096501414 modified "2023-09-26" @default.
• W2096501414 title "Microneedle assisted micro-particle delivery by gene guns: Mathematical model formulation and experimental verification" @default.
• W2096501414 cites W1965542359 @default.
• W2096501414 cites W1968127624 @default.
• W2096501414 cites W1976108766 @default.
• W2096501414 cites W1976627353 @default.
• W2096501414 cites W1976838182 @default.
• W2096501414 cites W1980895206 @default.
• W2096501414 cites W1985505368 @default.
• W2096501414 cites W1994623596 @default.
• W2096501414 cites W1997525021 @default.
• W2096501414 cites W2001890557 @default.
• W2096501414 cites W2007739515 @default.
• W2096501414 cites W2015143687 @default.
• W2096501414 cites W2016900988 @default.
• W2096501414 cites W2022552081 @default.
• W2096501414 cites W2026688235 @default.
• W2096501414 cites W2032378482 @default.
• W2096501414 cites W2035703000 @default.
• W2096501414 cites W2036908476 @default.
• W2096501414 cites W2038815967 @default.
• W2096501414 cites W2048388328 @default.
• W2096501414 cites W2051214467 @default.
• W2096501414 cites W2053518582 @default.
• W2096501414 cites W2054560842 @default.
• W2096501414 cites W2073968600 @default.
• W2096501414 cites W2083710819 @default.
• W2096501414 cites W2094914867 @default.
• W2096501414 cites W2106424445 @default.
• W2096501414 cites W2117453669 @default.
• W2096501414 cites W2118873626 @default.
• W2096501414 cites W2122396341 @default.
• W2096501414 cites W2124951578 @default.
• W2096501414 cites W2128671579 @default.
• W2096501414 cites W2138049174 @default.
• W2096501414 cites W2141095211 @default.
• W2096501414 cites W2143616792 @default.
• W2096501414 cites W2147323866 @default.
• W2096501414 cites W2150041965 @default.
• W2096501414 cites W2165467074 @default.
• W2096501414 cites W4230762911 @default.
• W2096501414 cites W2005045083 @default.
• W2096501414 doi "https://doi.org/10.1016/j.ces.2014.06.031" @default.
• W2096501414 hasPublicationYear "2015" @default.
• W2096501414 type Work @default.
• W2096501414 sameAs 2096501414 @default.
• W2096501414 citedByCount "4" @default.
• W2096501414 countsByYear W20965014142014 @default.
• W2096501414 countsByYear W20965014142017 @default.
• W2096501414 countsByYear W20965014142020 @default.
• W2096501414 countsByYear W20965014142021 @default.
• W2096501414 crossrefType "journal-article" @default.
• W2096501414 hasAuthorship W2096501414A5011151754 @default.
• W2096501414 hasAuthorship W2096501414A5018003703 @default.
• W2096501414 hasAuthorship W2096501414A5046274300 @default.
• W2096501414 hasBestOaLocation W20965014142 @default.
• W2096501414 hasConcept C104317684 @default.
• W2096501414 hasConcept C111368507 @default.
• W2096501414 hasConcept C120665830 @default.
• W2096501414 hasConcept C121332964 @default.
• W2096501414 hasConcept C127313418 @default.
• W2096501414 hasConcept C127413603 @default.
• W2096501414 hasConcept C135983454 @default.
• W2096501414 hasConcept C167508917 @default.
• W2096501414 hasConcept C168112101 @default.
• W2096501414 hasConcept C171250308 @default.
• W2096501414 hasConcept C185592680 @default.
• W2096501414 hasConcept C187530423 @default.
• W2096501414 hasConcept C192562407 @default.
• W2096501414 hasConcept C193493375 @default.
• W2096501414 hasConcept C22744801 @default.
• W2096501414 hasConcept C2778517922 @default.
• W2096501414 hasConcept C42360764 @default.
• W2096501414 hasConcept C42475967 @default.
• W2096501414 hasConcept C54009773 @default.
• W2096501414 hasConcept C552990157 @default.
• W2096501414 hasConcept C55493867 @default.
• W2096501414 hasConcept C57879066 @default.
• W2096501414 hasConcept C80107235 @default.
• W2096501414 hasConceptScore W2096501414C104317684 @default.
• W2096501414 hasConceptScore W2096501414C111368507 @default.
• W2096501414 hasConceptScore W2096501414C120665830 @default.
• W2096501414 hasConceptScore W2096501414C121332964 @default.
• W2096501414 hasConceptScore W2096501414C127313418 @default.
• W2096501414 hasConceptScore W2096501414C127413603 @default.
• W2096501414 hasConceptScore W2096501414C135983454 @default.
• W2096501414 hasConceptScore W2096501414C167508917 @default.
• W2096501414 hasConceptScore W2096501414C168112101 @default.
• W2096501414 hasConceptScore W2096501414C171250308 @default.
• W2096501414 hasConceptScore W2096501414C185592680 @default.
• W2096501414 hasConceptScore W2096501414C187530423 @default.
• W2096501414 hasConceptScore W2096501414C192562407 @default.

• next