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• W2096596075 abstract "1. Communication among cells, tissues and organ systems is essential for survival. Vertebrate and invertebrate animals rely primarily on three physiological systems for intra-organismal communication: the nervous, endocrine and immune systems. Rather than acting independently of one another, these systems communicate in an integrated fashion to coordinate suites of species-appropriate physiological and behavioural responses. 2. Our understanding of how these three systems are coordinated remains incomplete, in part because the importance of the immune system as part of this regulatory network has only recently been recognized. In contrast to the well-established integrative approach to the study of the endocrine and nervous systems, the study of immunity has traditionally occurred in relative isolation from other physiological systems. Immunity was typically considered to be largely buffered from environmental perturbations. 3. In the last several decades, however, this simplistic view has changed dramatically; we now know that a wide variety of extrinsic and intrinsic factors can affect immune responses (reviewed in: Ader, Felten & Cohen 2001). This altered perspective has led to the development of new scientific disciplines including psychoneuroimmunology (Ader & Cohen 1981) and ecological immunology (Sheldon & Verhulst 1996). 4. These new research fields focus on the connections among the endocrine, nervous and immune systems. These fields also examine how environmental factors influence interactions among the three systems, and the implications of these interactions for behaviour and host defence. A comparative approach will benefit the search for the adaptive functions of these interactions." @default.
• W2096596075 created "2016-06-24" @default.
• W2096596075 creator A5066663973 @default.
• W2096596075 creator A5080349520 @default.
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• W2096596075 date "2011-01-21" @default.
• W2096596075 modified "2023-10-01" @default.
• W2096596075 title "Neuroendocrine‐immune crosstalk in vertebrates and invertebrates: implications for host defence" @default.
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