FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096610096> ?p ?o ?g. }

• W2096610096 abstract "Probiotics are effective in inflammatory bowel diseases. Clinical effectiveness and dose dependency of E. coli Nissle (EcN) enemas were investigated in ulcerative colitis (UC). In a double-blind study, 90 patients with moderate distal activity in UC were randomly assigned to treatment with either 40, 20, or 10 ml enemas (N = 24, 23, 23) containing 10E8 EcN/ml or placebo (N = 20). The study medication was taken once daily for at least 2 weeks. After 2, 4 and/or 8 weeks the clinical DAI was assessed together with tolerance to treatment. Patients who reached clinical DAI ≤ 2 within that time were regarded as responders. According to ITT analysis the number of responders was not significantly higher in the EcN group than in the placebo group (p = 0.4430, 2-sided). However, the Jonckheere-Terpstra rank correlation for dose-dependent efficacy indicated a significant correlation of per-protocol responder rates (p = 0.0446, 2-sided). Time to remission was shortest with EcN 40 ml, followed by EcN 20 ml. The number of adverse events did not differ notably. In contrast to ITT analysis, efficacy of rectal EcN application was significant in PP and points to EcN as a well tolerated treatment alternative in moderate distal UC. German Clinical Trials Register DRK00000234." @default.
• W2096610096 created "2016-06-24" @default.
• W2096610096 creator A5006807147 @default.
• W2096610096 creator A5022903373 @default.
• W2096610096 creator A5036376627 @default.
• W2096610096 creator A5047776557 @default.
• W2096610096 creator A5068342884 @default.
• W2096610096 date "2010-04-15" @default.
• W2096610096 modified "2023-10-09" @default.
• W2096610096 title "Clinical trial: probiotic treatment of acute distal ulcerative colitis with rectally administered Escherichia coli Nissle 1917 (EcN)" @default.
• W2096610096 cites W1491953944 @default.
• W2096610096 cites W1971737706 @default.
• W2096610096 cites W1983967458 @default.
• W2096610096 cites W1985687346 @default.
• W2096610096 cites W1996896476 @default.
• W2096610096 cites W2006044054 @default.
• W2096610096 cites W2009496633 @default.
• W2096610096 cites W2011615352 @default.
• W2096610096 cites W2014818191 @default.
• W2096610096 cites W2018091449 @default.
• W2096610096 cites W2026723311 @default.
• W2096610096 cites W2032763010 @default.
• W2096610096 cites W2036746772 @default.
• W2096610096 cites W2048304047 @default.
• W2096610096 cites W2053013832 @default.
• W2096610096 cites W2056629400 @default.
• W2096610096 cites W2057003221 @default.
• W2096610096 cites W2061043651 @default.
• W2096610096 cites W2066094878 @default.
• W2096610096 cites W2076837393 @default.
• W2096610096 cites W2083594728 @default.
• W2096610096 cites W2116445664 @default.
• W2096610096 cites W2121650731 @default.
• W2096610096 cites W2124334818 @default.
• W2096610096 cites W2127190707 @default.
• W2096610096 cites W2142933567 @default.
• W2096610096 cites W2156807154 @default.
• W2096610096 cites W2158364865 @default.
• W2096610096 cites W2159907189 @default.
• W2096610096 doi "https://doi.org/10.1186/1472-6882-10-13" @default.
• W2096610096 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2861635" @default.
• W2096610096 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20398311" @default.
• W2096610096 hasPublicationYear "2010" @default.
• W2096610096 type Work @default.
• W2096610096 sameAs 2096610096 @default.
• W2096610096 citedByCount "159" @default.
• W2096610096 countsByYear W20966100962012 @default.
• W2096610096 countsByYear W20966100962013 @default.
• W2096610096 countsByYear W20966100962014 @default.
• W2096610096 countsByYear W20966100962015 @default.
• W2096610096 countsByYear W20966100962016 @default.
• W2096610096 countsByYear W20966100962017 @default.
• W2096610096 countsByYear W20966100962018 @default.
• W2096610096 countsByYear W20966100962019 @default.
• W2096610096 countsByYear W20966100962020 @default.
• W2096610096 countsByYear W20966100962021 @default.
• W2096610096 countsByYear W20966100962022 @default.
• W2096610096 countsByYear W20966100962023 @default.
• W2096610096 crossrefType "journal-article" @default.
• W2096610096 hasAuthorship W2096610096A5006807147 @default.
• W2096610096 hasAuthorship W2096610096A5022903373 @default.
• W2096610096 hasAuthorship W2096610096A5036376627 @default.
• W2096610096 hasAuthorship W2096610096A5047776557 @default.
• W2096610096 hasAuthorship W2096610096A5068342884 @default.
• W2096610096 hasBestOaLocation W20966100961 @default.
• W2096610096 hasConcept C126322002 @default.
• W2096610096 hasConcept C142724271 @default.
• W2096610096 hasConcept C197934379 @default.
• W2096610096 hasConcept C204787440 @default.
• W2096610096 hasConcept C27081682 @default.
• W2096610096 hasConcept C2779134260 @default.
• W2096610096 hasConcept C2780479503 @default.
• W2096610096 hasConcept C535046627 @default.
• W2096610096 hasConcept C71924100 @default.
• W2096610096 hasConcept C90924648 @default.
• W2096610096 hasConceptScore W2096610096C126322002 @default.
• W2096610096 hasConceptScore W2096610096C142724271 @default.
• W2096610096 hasConceptScore W2096610096C197934379 @default.
• W2096610096 hasConceptScore W2096610096C204787440 @default.
• W2096610096 hasConceptScore W2096610096C27081682 @default.
• W2096610096 hasConceptScore W2096610096C2779134260 @default.
• W2096610096 hasConceptScore W2096610096C2780479503 @default.
• W2096610096 hasConceptScore W2096610096C535046627 @default.
• W2096610096 hasConceptScore W2096610096C71924100 @default.
• W2096610096 hasConceptScore W2096610096C90924648 @default.
• W2096610096 hasIssue "1" @default.
• W2096610096 hasLocation W20966100961 @default.
• W2096610096 hasLocation W20966100962 @default.
• W2096610096 hasLocation W20966100963 @default.
• W2096610096 hasLocation W20966100964 @default.
• W2096610096 hasOpenAccess W2096610096 @default.
• W2096610096 hasPrimaryLocation W20966100961 @default.
• W2096610096 hasRelatedWork W1859326399 @default.
• W2096610096 hasRelatedWork W2085830368 @default.
• W2096610096 hasRelatedWork W2369056725 @default.
• W2096610096 hasRelatedWork W2378399001 @default.
• W2096610096 hasRelatedWork W2381376498 @default.
• W2096610096 hasRelatedWork W2393318770 @default.
• W2096610096 hasRelatedWork W2944370844 @default.
• W2096610096 hasRelatedWork W3151390891 @default.

• next