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- W2096640223 abstract "Studies on the mode of action of a series of bisphosphonates derived from fatty acids, which had previously proved to be potent inhibitors against Trypanosoma cruzi proliferation in in vitro assays, have been performed. Some of these drugs proved to be potent inhibitors against the intracellular form of the parasite, exhibiting IC(50) values at the low micromolar level. As bisphosphonates are FDA clinically approved for treatment of bone resorption disorders, their potential innocuousness makes them good candidates to control tropical diseases." @default.
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- W2096640223 date "2003-10-01" @default.
- W2096640223 modified "2023-10-17" @default.
- W2096640223 title "Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase" @default.
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- W2096640223 doi "https://doi.org/10.1016/s0960-894x(03)00663-2" @default.
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