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- W2096691640 abstract "Background. Cyclosporin A (CsA) nephrotoxicity has been attributed primarily to renal haemodynamic alterations caused by afferent arteriolar vasoconstriction. However, CsA nephropathy is also characterized by CsA-induced pre-glomerular disturbances and interstitial injury that may occur independently of haemodynamic changes. Given the high lipophilic activity of CsA, we hypothesized that direct tubular injury is likely to contribute to nephrotoxicity." @default.
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- W2096691640 date "2003-11-01" @default.
- W2096691640 modified "2023-09-23" @default.
- W2096691640 title "Cyclosporin A tubular effects contribute to nephrotoxicity: role for Ca2+ and Mg2+ ions" @default.
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- W2096691640 doi "https://doi.org/10.1093/ndt/gfg343" @default.
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