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- W2096758624 abstract "Pruritus, an early symptom of intrahepatic cholestasis of pregnancy, may be severe. Conventional treatment includes ursodeoxycholic acid and cholestyramine. Ondansetron, a 5‐hydroxytryptamine 3 receptor antagonist antiemetic, has been shown to reduce pruritus of different etiologies including cholestasis. We now report the successful preoperative use of ondansetron in a patient with pruritus from intrahepatic cholestasis of pregnancy. While the mechanism for our patient's response is poorly understood, 5‐hydroxytryptamine 3 receptor antagonists should be further evaluated and possibly considered as a treatment option for intrahepatic cholestasis of pregnancy‐related pruritus." @default.
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- W2096758624 date "2004-08-17" @default.
- W2096758624 modified "2023-10-16" @default.
- W2096758624 title "Cholestasis of pregnancy, pruritus and 5-hydroxytryptamine 3 receptor antagonists" @default.
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- W2096758624 doi "https://doi.org/10.1111/j.0001-6349.2004.00556.x" @default.
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