FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096819061> ?p ?o ?g. }

• W2096819061 endingPage "406" @default.
• W2096819061 startingPage "393" @default.
• W2096819061 abstract "The magnitude of the inner mitochondrial membrane potential (deltapsim) appears to influence the level of certain mitochondrial activities including regulation of ionic fluxes and ATP liberation, activities that are often compartmentalized or location dependent in cells. Recent evidence suggests that within cells, mitochondria can be heterogeneous with respect to deltapsim, and that high-polarized mitochondria (high deltapsim) may occur in the subplasmalemmal cytoplasm where intercellular contact is absent. Here, we investigated whether deltapsim in oocytes and preimplantation embryos was heterogeneous and cell contact-associated.Mouse and human oocytes and preimplantation stage embryos stained with mitochondria-specific probes rhodamine 123, MitoTracker Orange, and the deltapsim-sensitive probe JC-1, (5,5',6,6'-tetrachloro-1,1,3,3'-tetraethylbenzimidazoylcarbocyanine iodide), were examined by epifluorescence, scanning laser confocal, and transmission electron microscopy. The possibility that intercellular contact and deltapsim are associated was examined for oocytes, where transzonal coronal cell contacts were terminated naturally or experimentally, and for intact, disaggregated, and reconstructed cleavage stage mouse embryos.For both oocytes and embryos, clusters of apparently high-polarized mitochondria occur in the pericortical cytoplasm in regions free from intercellular contact.The findings suggest that mitochondria in oocytes and preimplantation embryos may be heterogeneous with respect to deltapsim. We propose that high-polarized pericortical mitochondria may have a role in the acquisition of oocyte competence and the regulation of early developmental processes that may be associated with elevated metabolism or intracellular signalling through calcium-induced calcium release pathways." @default.
• W2096819061 created "2016-06-24" @default.
• W2096819061 creator A5013469605 @default.
• W2096819061 creator A5054039730 @default.
• W2096819061 creator A5060458824 @default.
• W2096819061 creator A5062068422 @default.
• W2096819061 date "2002-02-01" @default.
• W2096819061 modified "2023-09-29" @default.
• W2096819061 title "Domains of high-polarized and low-polarized mitochondria may occur in mouse and human oocytes and early embryos" @default.
• W2096819061 cites W1484891956 @default.
• W2096819061 cites W1512984914 @default.
• W2096819061 cites W1537605674 @default.
• W2096819061 cites W1545168990 @default.
• W2096819061 cites W1972440163 @default.
• W2096819061 cites W1974129023 @default.
• W2096819061 cites W1974945118 @default.
• W2096819061 cites W1976675295 @default.
• W2096819061 cites W1980608195 @default.
• W2096819061 cites W2022436116 @default.
• W2096819061 cites W2028023732 @default.
• W2096819061 cites W2036546315 @default.
• W2096819061 cites W2037659354 @default.
• W2096819061 cites W2044248708 @default.
• W2096819061 cites W2052607700 @default.
• W2096819061 cites W2069798090 @default.
• W2096819061 cites W2070957905 @default.
• W2096819061 cites W2084665287 @default.
• W2096819061 cites W2097055795 @default.
• W2096819061 cites W2101875443 @default.
• W2096819061 cites W2109664810 @default.
• W2096819061 cites W2110345539 @default.
• W2096819061 cites W2112778436 @default.
• W2096819061 cites W2114388515 @default.
• W2096819061 cites W2115390828 @default.
• W2096819061 cites W2118521910 @default.
• W2096819061 cites W2135594458 @default.
• W2096819061 cites W2138592209 @default.
• W2096819061 cites W2147145982 @default.
• W2096819061 cites W2154346380 @default.
• W2096819061 cites W2161682861 @default.
• W2096819061 cites W2163519995 @default.
• W2096819061 cites W2165332793 @default.
• W2096819061 cites W2166053250 @default.
• W2096819061 cites W2168407561 @default.
• W2096819061 cites W2169232755 @default.
• W2096819061 cites W2171240877 @default.
• W2096819061 cites W2182955261 @default.
• W2096819061 cites W2255603483 @default.
• W2096819061 cites W2303712512 @default.
• W2096819061 cites W2336578011 @default.
• W2096819061 cites W2187267487 @default.
• W2096819061 doi "https://doi.org/10.1093/humrep/17.2.393" @default.
• W2096819061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11821285" @default.
• W2096819061 hasPublicationYear "2002" @default.
• W2096819061 type Work @default.
• W2096819061 sameAs 2096819061 @default.
• W2096819061 citedByCount "253" @default.
• W2096819061 countsByYear W20968190612012 @default.
• W2096819061 countsByYear W20968190612013 @default.
• W2096819061 countsByYear W20968190612014 @default.
• W2096819061 countsByYear W20968190612015 @default.
• W2096819061 countsByYear W20968190612016 @default.
• W2096819061 countsByYear W20968190612017 @default.
• W2096819061 countsByYear W20968190612018 @default.
• W2096819061 countsByYear W20968190612019 @default.
• W2096819061 countsByYear W20968190612020 @default.
• W2096819061 countsByYear W20968190612021 @default.
• W2096819061 countsByYear W20968190612022 @default.
• W2096819061 countsByYear W20968190612023 @default.
• W2096819061 crossrefType "journal-article" @default.
• W2096819061 hasAuthorship W2096819061A5013469605 @default.
• W2096819061 hasAuthorship W2096819061A5054039730 @default.
• W2096819061 hasAuthorship W2096819061A5060458824 @default.
• W2096819061 hasAuthorship W2096819061A5062068422 @default.
• W2096819061 hasBestOaLocation W20968190611 @default.
• W2096819061 hasConcept C190062978 @default.
• W2096819061 hasConcept C196843134 @default.
• W2096819061 hasConcept C2776690073 @default.
• W2096819061 hasConcept C28859421 @default.
• W2096819061 hasConcept C2994119143 @default.
• W2096819061 hasConcept C79879829 @default.
• W2096819061 hasConcept C86803240 @default.
• W2096819061 hasConcept C95444343 @default.
• W2096819061 hasConceptScore W2096819061C190062978 @default.
• W2096819061 hasConceptScore W2096819061C196843134 @default.
• W2096819061 hasConceptScore W2096819061C2776690073 @default.
• W2096819061 hasConceptScore W2096819061C28859421 @default.
• W2096819061 hasConceptScore W2096819061C2994119143 @default.
• W2096819061 hasConceptScore W2096819061C79879829 @default.
• W2096819061 hasConceptScore W2096819061C86803240 @default.
• W2096819061 hasConceptScore W2096819061C95444343 @default.
• W2096819061 hasIssue "2" @default.
• W2096819061 hasLocation W20968190611 @default.
• W2096819061 hasLocation W20968190612 @default.
• W2096819061 hasOpenAccess W2096819061 @default.
• W2096819061 hasPrimaryLocation W20968190611 @default.
• W2096819061 hasRelatedWork W1607170269 @default.
• W2096819061 hasRelatedWork W2008343297 @default.

• next