FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096826677> ?p ?o ?g. }

• W2096826677 endingPage "67" @default.
• W2096826677 startingPage "1057" @default.
• W2096826677 abstract "Pediatric hepatitis C mainly occurs through mother to child transmission, to date. Children usually present a mild disease, but they are not spared from its long-term complications. Thus this infection cannot be underestimated in children and intervention is necessary. Current treatment is based on the administration of pegylated-interferon associated with ribavirin, but few studies evaluated the efficacy and safety of this therapeutic protocol. Moreover, there is still no clarity on who, when and how to treat pediatric patients. This article, based on the information in literature, provides an overview of the main aspects of the disease, with particular attention to treatment.We describe the different treatment options available. About the association peginterferon plus ribavirin, we analyze thirteen non-randomized studies and one trial, found in recent literature. These studies are not directly compared because of differences in age, type of infection (vertical or not), viral genotypes and duration of treatment, between groups enrolled. The overall sustained viral response rate ranges from 28.6% to 81.8%. The rate of treatment success is higher in children infected with genotypes 2 and 3 than with other genotypes. The therapy does not induce severe adverse effects and children present better tolerance to antiviral than adults.The pharmacological efficacy of peginterferon and ribavirin seems to be proven by data collected in studies cited, but there are different opinions about who, when and how to treat children infected. Thus, further research is needed to define the best management of vertical acquired hepatitis C." @default.
• W2096826677 created "2016-06-24" @default.
• W2096826677 creator A5002822032 @default.
• W2096826677 creator A5028213193 @default.
• W2096826677 creator A5039313523 @default.
• W2096826677 creator A5059108311 @default.
• W2096826677 creator A5063731700 @default.
• W2096826677 creator A5067717684 @default.
• W2096826677 date "2011-09-01" @default.
• W2096826677 modified "2023-10-03" @default.
• W2096826677 title "Pediatric hepatitis C infection: to treat or not to treat...what's the best for the child?" @default.
• W2096826677 cites W1547384224 @default.
• W2096826677 cites W1967229580 @default.
• W2096826677 cites W1971011563 @default.
• W2096826677 cites W1977294239 @default.
• W2096826677 cites W1987371523 @default.
• W2096826677 cites W1989033233 @default.
• W2096826677 cites W1994947695 @default.
• W2096826677 cites W2002526645 @default.
• W2096826677 cites W2007931086 @default.
• W2096826677 cites W2010044342 @default.
• W2096826677 cites W2017726794 @default.
• W2096826677 cites W2018227824 @default.
• W2096826677 cites W2027476072 @default.
• W2096826677 cites W2034678334 @default.
• W2096826677 cites W2037584354 @default.
• W2096826677 cites W2040785319 @default.
• W2096826677 cites W2055613616 @default.
• W2096826677 cites W2057407106 @default.
• W2096826677 cites W2063692521 @default.
• W2096826677 cites W2064129992 @default.
• W2096826677 cites W2065631609 @default.
• W2096826677 cites W2069314327 @default.
• W2096826677 cites W2073128585 @default.
• W2096826677 cites W2074469671 @default.
• W2096826677 cites W2075282196 @default.
• W2096826677 cites W2087304793 @default.
• W2096826677 cites W2090296908 @default.
• W2096826677 cites W2102865648 @default.
• W2096826677 cites W2106791445 @default.
• W2096826677 cites W2112876622 @default.
• W2096826677 cites W2116296213 @default.
• W2096826677 cites W2142329259 @default.
• W2096826677 cites W2149999920 @default.
• W2096826677 cites W2152405299 @default.
• W2096826677 cites W2158566694 @default.
• W2096826677 cites W2293118025 @default.
• W2096826677 cites W2297070282 @default.
• W2096826677 cites W2314619766 @default.
• W2096826677 cites W2425739165 @default.
• W2096826677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22013729" @default.
• W2096826677 hasPublicationYear "2011" @default.
• W2096826677 type Work @default.
• W2096826677 sameAs 2096826677 @default.
• W2096826677 citedByCount "7" @default.
• W2096826677 countsByYear W20968266772012 @default.
• W2096826677 countsByYear W20968266772013 @default.
• W2096826677 countsByYear W20968266772014 @default.
• W2096826677 countsByYear W20968266772017 @default.
• W2096826677 countsByYear W20968266772018 @default.
• W2096826677 countsByYear W20968266772019 @default.
• W2096826677 crossrefType "journal-article" @default.
• W2096826677 hasAuthorship W2096826677A5002822032 @default.
• W2096826677 hasAuthorship W2096826677A5028213193 @default.
• W2096826677 hasAuthorship W2096826677A5039313523 @default.
• W2096826677 hasAuthorship W2096826677A5059108311 @default.
• W2096826677 hasAuthorship W2096826677A5063731700 @default.
• W2096826677 hasAuthorship W2096826677A5067717684 @default.
• W2096826677 hasConcept C119599485 @default.
• W2096826677 hasConcept C126322002 @default.
• W2096826677 hasConcept C127413603 @default.
• W2096826677 hasConcept C168563851 @default.
• W2096826677 hasConcept C177713679 @default.
• W2096826677 hasConcept C187212893 @default.
• W2096826677 hasConcept C197934379 @default.
• W2096826677 hasConcept C203014093 @default.
• W2096826677 hasConcept C2522874641 @default.
• W2096826677 hasConcept C2776408679 @default.
• W2096826677 hasConcept C2776455275 @default.
• W2096826677 hasConcept C2776461080 @default.
• W2096826677 hasConcept C2779134260 @default.
• W2096826677 hasConcept C2780040827 @default.
• W2096826677 hasConcept C71924100 @default.
• W2096826677 hasConcept C761482 @default.
• W2096826677 hasConceptScore W2096826677C119599485 @default.
• W2096826677 hasConceptScore W2096826677C126322002 @default.
• W2096826677 hasConceptScore W2096826677C127413603 @default.
• W2096826677 hasConceptScore W2096826677C168563851 @default.
• W2096826677 hasConceptScore W2096826677C177713679 @default.
• W2096826677 hasConceptScore W2096826677C187212893 @default.
• W2096826677 hasConceptScore W2096826677C197934379 @default.
• W2096826677 hasConceptScore W2096826677C203014093 @default.
• W2096826677 hasConceptScore W2096826677C2522874641 @default.
• W2096826677 hasConceptScore W2096826677C2776408679 @default.
• W2096826677 hasConceptScore W2096826677C2776455275 @default.
• W2096826677 hasConceptScore W2096826677C2776461080 @default.
• W2096826677 hasConceptScore W2096826677C2779134260 @default.
• W2096826677 hasConceptScore W2096826677C2780040827 @default.

• next