FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096873190> ?p ?o ?g. }

• W2096873190 endingPage "83" @default.
• W2096873190 startingPage "77" @default.
• W2096873190 abstract "Rhoeo discolor is a legendary plant used for treatment of superficial mycoses in Mexican traditional medicine. Despite its extended use, it is not known whether it has side-effects. An ethanolic crude extract from Rhoeo discolor was prepared, its mutagenic capacity was investigated by the Ames test, and its genotoxic activity in primary liver cell cultures using the unscheduled DNA synthesis assay. This extract was not mutagenic when tested with Salmonella typhimurium strains TA97, TA98 and TA100, and it did not elicit unscheduled DNA synthesis in hepatocyte cultures. In addition, we explored the antimutagenic and antigenotoxic activities of the extract and its ROS scavenger behaviour. Our results show that Rhoeo extract is antimutagenic for S. typhimurium strain TA102 pretreated with ROS-generating mutagen norfloxacin in the Ames test, and protects liver cell cultures against diethylnitrosamine induction of unscheduled DNA synthesis even at 1.9 ng per dish, which was the lowest dose tested. A free radical scavenging test was used in order to explore the antioxidant capacity of Rhoeo extract, as compared with three commercial well-known antioxidants quercetin, ascorbic acid and tocopherol. Rhoeo extract showed less radical scavenging effect than quercetin, but similar to that of alpha-tocopherol and more than ascorbic acid. It is important to note that this extract was neither mutagenic in S. typhimurium nor genotoxic in liver cell culture, even at concentrations as high as four- and 166-fold of those needed for maximal antimutagenic or chemoprotective activities, respectively." @default.
• W2096873190 created "2016-06-24" @default.
• W2096873190 creator A5014447209 @default.
• W2096873190 creator A5047543592 @default.
• W2096873190 creator A5049294083 @default.
• W2096873190 creator A5053871509 @default.
• W2096873190 creator A5062216525 @default.
• W2096873190 creator A5067692613 @default.
• W2096873190 creator A5072897230 @default.
• W2096873190 date "2003-02-01" @default.
• W2096873190 modified "2023-10-18" @default.
• W2096873190 title "Antigenotoxic, antimutagenic and ROS scavenging activities of a Rhoeo discolor ethanolic crude extract" @default.
• W2096873190 cites W1906197854 @default.
• W2096873190 cites W1961671088 @default.
• W2096873190 cites W1964666593 @default.
• W2096873190 cites W1967532347 @default.
• W2096873190 cites W1973727997 @default.
• W2096873190 cites W1975325378 @default.
• W2096873190 cites W1988440183 @default.
• W2096873190 cites W1993618051 @default.
• W2096873190 cites W1994709591 @default.
• W2096873190 cites W2003856166 @default.
• W2096873190 cites W2005156172 @default.
• W2096873190 cites W2007432088 @default.
• W2096873190 cites W2011526575 @default.
• W2096873190 cites W2021709131 @default.
• W2096873190 cites W2037569912 @default.
• W2096873190 cites W2045023739 @default.
• W2096873190 cites W2060969280 @default.
• W2096873190 cites W2071980159 @default.
• W2096873190 cites W2073766816 @default.
• W2096873190 cites W2086657884 @default.
• W2096873190 cites W2089961689 @default.
• W2096873190 cites W2092674578 @default.
• W2096873190 cites W2094779562 @default.
• W2096873190 cites W2104705851 @default.
• W2096873190 cites W2109450525 @default.
• W2096873190 cites W2134824140 @default.
• W2096873190 cites W2156413500 @default.
• W2096873190 cites W3004990870 @default.
• W2096873190 cites W4252635440 @default.
• W2096873190 cites W4300887279 @default.
• W2096873190 doi "https://doi.org/10.1016/s0887-2333(02)00120-0" @default.
• W2096873190 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12537965" @default.
• W2096873190 hasPublicationYear "2003" @default.
• W2096873190 type Work @default.
• W2096873190 sameAs 2096873190 @default.
• W2096873190 citedByCount "55" @default.
• W2096873190 countsByYear W20968731902012 @default.
• W2096873190 countsByYear W20968731902013 @default.
• W2096873190 countsByYear W20968731902014 @default.
• W2096873190 countsByYear W20968731902015 @default.
• W2096873190 countsByYear W20968731902016 @default.
• W2096873190 countsByYear W20968731902017 @default.
• W2096873190 countsByYear W20968731902018 @default.
• W2096873190 countsByYear W20968731902021 @default.
• W2096873190 countsByYear W20968731902022 @default.
• W2096873190 countsByYear W20968731902023 @default.
• W2096873190 crossrefType "journal-article" @default.
• W2096873190 hasAuthorship W2096873190A5014447209 @default.
• W2096873190 hasAuthorship W2096873190A5047543592 @default.
• W2096873190 hasAuthorship W2096873190A5049294083 @default.
• W2096873190 hasAuthorship W2096873190A5053871509 @default.
• W2096873190 hasAuthorship W2096873190A5062216525 @default.
• W2096873190 hasAuthorship W2096873190A5067692613 @default.
• W2096873190 hasAuthorship W2096873190A5072897230 @default.
• W2096873190 hasBestOaLocation W20968731901 @default.
• W2096873190 hasConcept C117632636 @default.
• W2096873190 hasConcept C185592680 @default.
• W2096873190 hasConcept C2776639595 @default.
• W2096873190 hasConcept C2777551382 @default.
• W2096873190 hasConcept C2778004101 @default.
• W2096873190 hasConcept C2781065037 @default.
• W2096873190 hasConcept C2781263971 @default.
• W2096873190 hasConcept C2781422964 @default.
• W2096873190 hasConcept C2781449162 @default.
• W2096873190 hasConcept C2986274086 @default.
• W2096873190 hasConcept C31903555 @default.
• W2096873190 hasConcept C523546767 @default.
• W2096873190 hasConcept C54355233 @default.
• W2096873190 hasConcept C552990157 @default.
• W2096873190 hasConcept C55493867 @default.
• W2096873190 hasConcept C556039675 @default.
• W2096873190 hasConcept C56783068 @default.
• W2096873190 hasConcept C71924100 @default.
• W2096873190 hasConcept C86803240 @default.
• W2096873190 hasConceptScore W2096873190C117632636 @default.
• W2096873190 hasConceptScore W2096873190C185592680 @default.
• W2096873190 hasConceptScore W2096873190C2776639595 @default.
• W2096873190 hasConceptScore W2096873190C2777551382 @default.
• W2096873190 hasConceptScore W2096873190C2778004101 @default.
• W2096873190 hasConceptScore W2096873190C2781065037 @default.
• W2096873190 hasConceptScore W2096873190C2781263971 @default.
• W2096873190 hasConceptScore W2096873190C2781422964 @default.
• W2096873190 hasConceptScore W2096873190C2781449162 @default.
• W2096873190 hasConceptScore W2096873190C2986274086 @default.
• W2096873190 hasConceptScore W2096873190C31903555 @default.
• W2096873190 hasConceptScore W2096873190C523546767 @default.

• next