FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2096976388> ?p ?o ?g. }

• W2096976388 endingPage "191" @default.
• W2096976388 startingPage "183" @default.
• W2096976388 abstract "Previously, we observed that sustained activation of P2Y1 leads to inhibition of Na+,K+,Cl− cotransport (NKCC) in C11 cells resembling intercalated cells from collecting ducts of the Madin-Darby canine kidney. This study examined the role of stress-activated protein kinases (SAPK) in NKCC inhibition triggered by purinergic receptors. Treatment of C11 cells with ATP led to sustained phosphorylation of SAPK such as JNK and p38. Activation of these kinases also occurred in anisomycin-treated cells. Surprisingly, we observed that compounds SP600125 and SB202190, known as potent inhibitors of JNK and p38 in cell-free systems, activated rather than inhibited phosphorylation of the kinases in C11 cells. Importantly, similarly to ATP, all the above-listed activators of JNK and p38 phosphorylation inhibited NKCC. Thus, our results suggest that activation of JNK and/or p38 contributes to NKCC suppression detected in intercalated-like cells from distal tubules after their exposure to P2Y1 agonists." @default.
• W2096976388 created "2016-06-24" @default.
• W2096976388 creator A5021356786 @default.
• W2096976388 creator A5031351161 @default.
• W2096976388 creator A5036314502 @default.
• W2096976388 creator A5057400741 @default.
• W2096976388 date "2007-06-30" @default.
• W2096976388 modified "2023-09-27" @default.
• W2096976388 title "Purinergic inhibition of Na+,K+,Cl− cotransport in C11-MDCK cells: Role of stress-activated protein kinases" @default.
• W2096976388 cites W1546941284 @default.
• W2096976388 cites W1964968706 @default.
• W2096976388 cites W1966399746 @default.
• W2096976388 cites W1970465585 @default.
• W2096976388 cites W1973469920 @default.
• W2096976388 cites W1974204965 @default.
• W2096976388 cites W1975146387 @default.
• W2096976388 cites W1979793199 @default.
• W2096976388 cites W1986855417 @default.
• W2096976388 cites W1987751707 @default.
• W2096976388 cites W1988071723 @default.
• W2096976388 cites W1988201508 @default.
• W2096976388 cites W1989968095 @default.
• W2096976388 cites W1995994950 @default.
• W2096976388 cites W2004516283 @default.
• W2096976388 cites W2008418924 @default.
• W2096976388 cites W2011319493 @default.
• W2096976388 cites W2026122406 @default.
• W2096976388 cites W2027226283 @default.
• W2096976388 cites W2036652037 @default.
• W2096976388 cites W2046892943 @default.
• W2096976388 cites W2050187348 @default.
• W2096976388 cites W2051915150 @default.
• W2096976388 cites W2052750950 @default.
• W2096976388 cites W2058753941 @default.
• W2096976388 cites W2065314664 @default.
• W2096976388 cites W2065471638 @default.
• W2096976388 cites W2068404710 @default.
• W2096976388 cites W2080854317 @default.
• W2096976388 cites W2084439861 @default.
• W2096976388 cites W2096931514 @default.
• W2096976388 cites W2101595617 @default.
• W2096976388 cites W2111395353 @default.
• W2096976388 cites W2117383933 @default.
• W2096976388 cites W2123307919 @default.
• W2096976388 cites W2131163999 @default.
• W2096976388 cites W2131801982 @default.
• W2096976388 cites W2138930964 @default.
• W2096976388 cites W2143621517 @default.
• W2096976388 cites W2158738489 @default.
• W2096976388 cites W2314147402 @default.
• W2096976388 doi "https://doi.org/10.1007/s11302-007-9057-z" @default.
• W2096976388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2377324" @default.
• W2096976388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18368525" @default.
• W2096976388 hasPublicationYear "2007" @default.
• W2096976388 type Work @default.
• W2096976388 sameAs 2096976388 @default.
• W2096976388 citedByCount "5" @default.
• W2096976388 countsByYear W20969763882013 @default.
• W2096976388 countsByYear W20969763882016 @default.
• W2096976388 crossrefType "journal-article" @default.
• W2096976388 hasAuthorship W2096976388A5021356786 @default.
• W2096976388 hasAuthorship W2096976388A5031351161 @default.
• W2096976388 hasAuthorship W2096976388A5036314502 @default.
• W2096976388 hasAuthorship W2096976388A5057400741 @default.
• W2096976388 hasBestOaLocation W20969763881 @default.
• W2096976388 hasConcept C11960822 @default.
• W2096976388 hasConcept C132149769 @default.
• W2096976388 hasConcept C178790620 @default.
• W2096976388 hasConcept C184235292 @default.
• W2096976388 hasConcept C185592680 @default.
• W2096976388 hasConcept C188053792 @default.
• W2096976388 hasConcept C2778073123 @default.
• W2096976388 hasConcept C28406088 @default.
• W2096976388 hasConcept C51551487 @default.
• W2096976388 hasConcept C537181965 @default.
• W2096976388 hasConcept C57306754 @default.
• W2096976388 hasConcept C86803240 @default.
• W2096976388 hasConcept C95444343 @default.
• W2096976388 hasConcept C97029542 @default.
• W2096976388 hasConceptScore W2096976388C11960822 @default.
• W2096976388 hasConceptScore W2096976388C132149769 @default.
• W2096976388 hasConceptScore W2096976388C178790620 @default.
• W2096976388 hasConceptScore W2096976388C184235292 @default.
• W2096976388 hasConceptScore W2096976388C185592680 @default.
• W2096976388 hasConceptScore W2096976388C188053792 @default.
• W2096976388 hasConceptScore W2096976388C2778073123 @default.
• W2096976388 hasConceptScore W2096976388C28406088 @default.
• W2096976388 hasConceptScore W2096976388C51551487 @default.
• W2096976388 hasConceptScore W2096976388C537181965 @default.
• W2096976388 hasConceptScore W2096976388C57306754 @default.
• W2096976388 hasConceptScore W2096976388C86803240 @default.
• W2096976388 hasConceptScore W2096976388C95444343 @default.
• W2096976388 hasConceptScore W2096976388C97029542 @default.
• W2096976388 hasIssue "2" @default.
• W2096976388 hasLocation W20969763881 @default.
• W2096976388 hasLocation W20969763882 @default.
• W2096976388 hasLocation W20969763883 @default.
• W2096976388 hasLocation W20969763884 @default.

• next