FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097019712> ?p ?o ?g. }

• W2097019712 abstract "Childhood obesity is a significant risk factor for cardiovascular disease in adulthood. Although ventricular remodeling has been reported in obese youth, early tissue-level markers within the myocardium that precede organ-level alterations have not been described.We studied 21 obese adolescents (mean age, 17.7±2.6 years; mean body mass index [BMI], 41.9±9.5 kg/m(2), including 11 patients with type 2 diabetes [T2D]) and 12 healthy volunteers (age, 15.1±4.5 years; BMI, 20.1±3.5 kg/m(2)) using biomarkers of cardiometabolic risk and cardiac magnetic resonance imaging (CMR) to phenotype cardiac structure, function, and interstitial matrix remodeling by standard techniques. Although left ventricular ejection fraction and left atrial volumes were similar in healthy volunteers and obese patients (and within normal body size-adjusted limits), interstitial matrix expansion by CMR extracellular volume fraction (ECV) was significantly different between healthy volunteers (median, 0.264; interquartile range [IQR], 0.253 to 0.271), obese adolescents without T2D (median, 0.328; IQR, 0.278 to 0.345), and obese adolescents with T2D (median, 0.376; IQR, 0.336 to 0.407; P=0.0001). ECV was associated with BMI for the entire population (r=0.58, P<0.001) and with high-sensitivity C-reactive protein (r=0.47, P<0.05), serum triglycerides (r=0.51, P<0.05), and hemoglobin A1c (r=0.76, P<0.0001) in the obese stratum.Obese adolescents (particularly those with T2D) have subclinical alterations in myocardial tissue architecture associated with inflammation and insulin resistance. These alterations precede significant left ventricular hypertrophy or decreased cardiac function." @default.
• W2097019712 created "2016-06-24" @default.
• W2097019712 creator A5001031174 @default.
• W2097019712 creator A5005763249 @default.
• W2097019712 creator A5010778205 @default.
• W2097019712 creator A5013418419 @default.
• W2097019712 creator A5018509311 @default.
• W2097019712 creator A5018910105 @default.
• W2097019712 creator A5019717682 @default.
• W2097019712 creator A5024059482 @default.
• W2097019712 creator A5036756435 @default.
• W2097019712 creator A5045511176 @default.
• W2097019712 creator A5047081562 @default.
• W2097019712 creator A5052358762 @default.
• W2097019712 creator A5056428329 @default.
• W2097019712 creator A5079317352 @default.
• W2097019712 creator A5079521310 @default.
• W2097019712 creator A5081704681 @default.
• W2097019712 creator A5083253617 @default.
• W2097019712 creator A5083307413 @default.
• W2097019712 creator A5084430398 @default.
• W2097019712 creator A5087164932 @default.
• W2097019712 date "2013-08-22" @default.
• W2097019712 modified "2023-10-16" @default.
• W2097019712 title "Myocardial Tissue Remodeling in Adolescent Obesity" @default.
• W2097019712 cites W129855031 @default.
• W2097019712 cites W1772253419 @default.
• W2097019712 cites W1838167348 @default.
• W2097019712 cites W1964864891 @default.
• W2097019712 cites W1983283029 @default.
• W2097019712 cites W1998667812 @default.
• W2097019712 cites W2008255759 @default.
• W2097019712 cites W2011068925 @default.
• W2097019712 cites W2011216927 @default.
• W2097019712 cites W2016738173 @default.
• W2097019712 cites W2022195092 @default.
• W2097019712 cites W2028744383 @default.
• W2097019712 cites W2037706689 @default.
• W2097019712 cites W2046606573 @default.
• W2097019712 cites W2047942656 @default.
• W2097019712 cites W2049749994 @default.
• W2097019712 cites W2054005523 @default.
• W2097019712 cites W2054911255 @default.
• W2097019712 cites W2059563252 @default.
• W2097019712 cites W2060762923 @default.
• W2097019712 cites W2067044819 @default.
• W2097019712 cites W2069830389 @default.
• W2097019712 cites W2070150432 @default.
• W2097019712 cites W2074850911 @default.
• W2097019712 cites W2075445452 @default.
• W2097019712 cites W2076467505 @default.
• W2097019712 cites W2077741425 @default.
• W2097019712 cites W2084552642 @default.
• W2097019712 cites W2092509345 @default.
• W2097019712 cites W2095401314 @default.
• W2097019712 cites W2096278840 @default.
• W2097019712 cites W2102775774 @default.
• W2097019712 cites W2103678211 @default.
• W2097019712 cites W2111053427 @default.
• W2097019712 cites W2111161258 @default.
• W2097019712 cites W2119130655 @default.
• W2097019712 cites W2126090408 @default.
• W2097019712 cites W2140912550 @default.
• W2097019712 cites W2146575867 @default.
• W2097019712 cites W2149354290 @default.
• W2097019712 cites W2152160146 @default.
• W2097019712 cites W2154524666 @default.
• W2097019712 cites W2159716287 @default.
• W2097019712 cites W2547652217 @default.
• W2097019712 cites W4236185742 @default.
• W2097019712 cites W58359368 @default.
• W2097019712 doi "https://doi.org/10.1161/jaha.113.000279" @default.
• W2097019712 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3828806" @default.
• W2097019712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23963758" @default.
• W2097019712 hasPublicationYear "2013" @default.
• W2097019712 type Work @default.
• W2097019712 sameAs 2097019712 @default.
• W2097019712 citedByCount "46" @default.
• W2097019712 countsByYear W20970197122013 @default.
• W2097019712 countsByYear W20970197122014 @default.
• W2097019712 countsByYear W20970197122015 @default.
• W2097019712 countsByYear W20970197122016 @default.
• W2097019712 countsByYear W20970197122017 @default.
• W2097019712 countsByYear W20970197122018 @default.
• W2097019712 countsByYear W20970197122019 @default.
• W2097019712 countsByYear W20970197122020 @default.
• W2097019712 countsByYear W20970197122021 @default.
• W2097019712 countsByYear W20970197122022 @default.
• W2097019712 countsByYear W20970197122023 @default.
• W2097019712 crossrefType "journal-article" @default.
• W2097019712 hasAuthorship W2097019712A5001031174 @default.
• W2097019712 hasAuthorship W2097019712A5005763249 @default.
• W2097019712 hasAuthorship W2097019712A5010778205 @default.
• W2097019712 hasAuthorship W2097019712A5013418419 @default.
• W2097019712 hasAuthorship W2097019712A5018509311 @default.
• W2097019712 hasAuthorship W2097019712A5018910105 @default.
• W2097019712 hasAuthorship W2097019712A5019717682 @default.
• W2097019712 hasAuthorship W2097019712A5024059482 @default.
• W2097019712 hasAuthorship W2097019712A5036756435 @default.
• W2097019712 hasAuthorship W2097019712A5045511176 @default.

• next