Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097020148> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2097020148 abstract "Infectious diseases produced by Enterococcus spp, must be treated with a synergistic combination between a penicillin and an aminoglycoside. High level resistance to aminoglycosides is a serious therapeutic problem, since it predicts the loss of synergistic activity of this antimicrobial combination.To investigate the presence of genes encoding aminoglycoside-modifying enzymes (AMEs) among strains of Enterococcus spp with high level of resistance to aminoglycosides.The genes encoding some of the AMEs were investigated among 305 aminoglycoside-resistant strains of Enterococcus spp isolated in hospitals of the VIII region of Chile, by dot blot hybridization and Polymerase Chain Reaction (PCS).High level resistance to some aminoglycosides was observed in 104 strains (34.1 %) and 93 of these harbored at least one of the genes encoding the investigated AMEs. Three genes were detected: aac(6)Ie-aph(2)Ia (14.8%) encoding for the enzyme AAC(6)Ie-APH(2)Ia (resistance to all aminoglycosides, except streptomycin); aph(3)IIIa (26%), and ant(6)la (28.5%) encoding for the phosphorylating enzymes APH(3)Ilia (resistance to kanamycin, amikacin and neomycin), and ANT(6)-la (resistance only to streptomycin), respectively. None of the strains harbored the gene ant (4) which encode for the enzyme ANT (4).The low frequency of strains harbouring the bifunctional enzyme (<15%), conferring an extended resistance profile to aminoglycosides, allows us to propose the empirical use of aminoglycoside-aminocyclitols, associated to a penicillin, in the treatment of serious infections produced by species of enterococci." @default.
- W2097020148 created "2016-06-24" @default.
- W2097020148 creator A5004034267 @default.
- W2097020148 creator A5011534818 @default.
- W2097020148 creator A5060656717 @default.
- W2097020148 creator A5068721190 @default.
- W2097020148 creator A5081270513 @default.
- W2097020148 creator A5090556111 @default.
- W2097020148 date "2007-05-01" @default.
- W2097020148 modified "2023-10-16" @default.
- W2097020148 title "Identificación molecular de enzimas modificantes de aminoglucósidos en cepas de Enterococcus spp. aisladas en hospitales de la Octava Región de Chile" @default.
- W2097020148 cites W1653306470 @default.
- W2097020148 cites W1915532564 @default.
- W2097020148 cites W1938569590 @default.
- W2097020148 cites W1981059437 @default.
- W2097020148 cites W1992770289 @default.
- W2097020148 cites W1997501636 @default.
- W2097020148 cites W2011845141 @default.
- W2097020148 cites W2024642722 @default.
- W2097020148 cites W2050894817 @default.
- W2097020148 cites W2055413233 @default.
- W2097020148 cites W2126524876 @default.
- W2097020148 cites W2127777447 @default.
- W2097020148 cites W2139374860 @default.
- W2097020148 cites W2140303909 @default.
- W2097020148 cites W2415733905 @default.
- W2097020148 cites W2419529702 @default.
- W2097020148 doi "https://doi.org/10.4067/s0034-98872007000500003" @default.
- W2097020148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17657324" @default.
- W2097020148 hasPublicationYear "2007" @default.
- W2097020148 type Work @default.
- W2097020148 sameAs 2097020148 @default.
- W2097020148 citedByCount "7" @default.
- W2097020148 countsByYear W20970201482016 @default.
- W2097020148 countsByYear W20970201482020 @default.
- W2097020148 countsByYear W20970201482021 @default.
- W2097020148 crossrefType "journal-article" @default.
- W2097020148 hasAuthorship W2097020148A5004034267 @default.
- W2097020148 hasAuthorship W2097020148A5011534818 @default.
- W2097020148 hasAuthorship W2097020148A5060656717 @default.
- W2097020148 hasAuthorship W2097020148A5068721190 @default.
- W2097020148 hasAuthorship W2097020148A5081270513 @default.
- W2097020148 hasAuthorship W2097020148A5090556111 @default.
- W2097020148 hasBestOaLocation W20970201481 @default.
- W2097020148 hasConcept C104317684 @default.
- W2097020148 hasConcept C174802600 @default.
- W2097020148 hasConcept C2775843808 @default.
- W2097020148 hasConcept C2777427914 @default.
- W2097020148 hasConcept C2777787772 @default.
- W2097020148 hasConcept C2780585763 @default.
- W2097020148 hasConcept C2780920689 @default.
- W2097020148 hasConcept C501593827 @default.
- W2097020148 hasConcept C54355233 @default.
- W2097020148 hasConcept C86803240 @default.
- W2097020148 hasConcept C89423630 @default.
- W2097020148 hasConceptScore W2097020148C104317684 @default.
- W2097020148 hasConceptScore W2097020148C174802600 @default.
- W2097020148 hasConceptScore W2097020148C2775843808 @default.
- W2097020148 hasConceptScore W2097020148C2777427914 @default.
- W2097020148 hasConceptScore W2097020148C2777787772 @default.
- W2097020148 hasConceptScore W2097020148C2780585763 @default.
- W2097020148 hasConceptScore W2097020148C2780920689 @default.
- W2097020148 hasConceptScore W2097020148C501593827 @default.
- W2097020148 hasConceptScore W2097020148C54355233 @default.
- W2097020148 hasConceptScore W2097020148C86803240 @default.
- W2097020148 hasConceptScore W2097020148C89423630 @default.
- W2097020148 hasIssue "5" @default.
- W2097020148 hasLocation W20970201481 @default.
- W2097020148 hasLocation W20970201482 @default.
- W2097020148 hasOpenAccess W2097020148 @default.
- W2097020148 hasPrimaryLocation W20970201481 @default.
- W2097020148 hasRelatedWork W1846767563 @default.
- W2097020148 hasRelatedWork W1940669354 @default.
- W2097020148 hasRelatedWork W2033569039 @default.
- W2097020148 hasRelatedWork W2048476241 @default.
- W2097020148 hasRelatedWork W2069496976 @default.
- W2097020148 hasRelatedWork W2113589559 @default.
- W2097020148 hasRelatedWork W2125870968 @default.
- W2097020148 hasRelatedWork W2146464771 @default.
- W2097020148 hasRelatedWork W2152574481 @default.
- W2097020148 hasRelatedWork W2334517927 @default.
- W2097020148 hasVolume "135" @default.
- W2097020148 isParatext "false" @default.
- W2097020148 isRetracted "false" @default.
- W2097020148 magId "2097020148" @default.
- W2097020148 workType "article" @default.