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- W2097047342 abstract "The 1,25-dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) receptor mediates many of the actions of 1,25(OH) 2 D 3 in cells of target tissues. Abnormalities in vitamin D receptor concentration and regulation exist in tissues of subjects with chronic renal failure and end-stage renal disease. There is evidence that inhibitors of vitamin D receptor- 1,25(OH) 2 D 3 binding and 1,25(OH) 2 D 3 action are present in dialysates and sera of individuals with end-stage renal disease. The biological significance of decreased vitamin D receptor number and altered vitamin D receptor regulation in uraemia is unclear at present as responses to 1,25(OH) 2 D 3 in uraemia have not been systematically compared with responses in normal subjects." @default.
- W2097047342 created "2016-06-24" @default.
- W2097047342 creator A5086083991 @default.
- W2097047342 date "1996-01-01" @default.
- W2097047342 modified "2023-09-26" @default.
- W2097047342 title "Abnormalities of the vitamin D receptor in uraemia" @default.
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- W2097047342 doi "https://doi.org/10.1093/ndt/11.supp3.6" @default.
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