Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097059462> ?p ?o ?g. }
- W2097059462 endingPage "22" @default.
- W2097059462 startingPage "8" @default.
- W2097059462 abstract "Abstract: Hepatic fibrosis is the common wound‐healing response to chronic liver injury. In this process, activation of hepatic stellate cells is characteristic of cell proliferation and migration, production of collagen and other extracellular matrix (ECM) molecules, and contraction after transforming into myofibroblasts. It has been shown that the fibrogenic process is prominently regulated by transforming growth factor‐β1 (TGF‐β1) and that the specific blockade of TGF‐β1/Smad3 signaling may therapeutically intervene the fibrosis of various tissues. In this review, we attempt to integrate recent advances in the understanding of the mechanisms underlying TGF‐β1/Smad3 pathway modulation of ECM gene expression in the context of liver fibrosis, discuss intervention strategies targeting the blockade of related signal pathways, and look into novel ways to the safe and efficacious prevention and treatment of hepatic fibrosis." @default.
- W2097059462 created "2016-06-24" @default.
- W2097059462 creator A5017952517 @default.
- W2097059462 creator A5078220443 @default.
- W2097059462 creator A5086637212 @default.
- W2097059462 date "2005-11-07" @default.
- W2097059462 modified "2023-10-13" @default.
- W2097059462 title "Therapeutic strategies against TGF-β signaling pathway in hepatic fibrosis" @default.
- W2097059462 cites W1520170725 @default.
- W2097059462 cites W1536476892 @default.
- W2097059462 cites W1549555023 @default.
- W2097059462 cites W1553444759 @default.
- W2097059462 cites W1565561072 @default.
- W2097059462 cites W1572409531 @default.
- W2097059462 cites W1574615823 @default.
- W2097059462 cites W1663371441 @default.
- W2097059462 cites W1747761114 @default.
- W2097059462 cites W1905104097 @default.
- W2097059462 cites W1957112060 @default.
- W2097059462 cites W1965783459 @default.
- W2097059462 cites W1965790286 @default.
- W2097059462 cites W1966939472 @default.
- W2097059462 cites W196842000 @default.
- W2097059462 cites W1970932524 @default.
- W2097059462 cites W1972403135 @default.
- W2097059462 cites W1972917598 @default.
- W2097059462 cites W1973301143 @default.
- W2097059462 cites W1975710755 @default.
- W2097059462 cites W1976123775 @default.
- W2097059462 cites W1978146894 @default.
- W2097059462 cites W1978999523 @default.
- W2097059462 cites W1983912684 @default.
- W2097059462 cites W1987291131 @default.
- W2097059462 cites W1987701650 @default.
- W2097059462 cites W1988613013 @default.
- W2097059462 cites W1989050480 @default.
- W2097059462 cites W1990448161 @default.
- W2097059462 cites W1991082072 @default.
- W2097059462 cites W1991341426 @default.
- W2097059462 cites W1992213652 @default.
- W2097059462 cites W1992425189 @default.
- W2097059462 cites W1993891700 @default.
- W2097059462 cites W1999756883 @default.
- W2097059462 cites W2003660205 @default.
- W2097059462 cites W2008870589 @default.
- W2097059462 cites W2011062520 @default.
- W2097059462 cites W2011957610 @default.
- W2097059462 cites W2017463647 @default.
- W2097059462 cites W2021484300 @default.
- W2097059462 cites W2023121345 @default.
- W2097059462 cites W2023752082 @default.
- W2097059462 cites W2024160852 @default.
- W2097059462 cites W2024888501 @default.
- W2097059462 cites W2025620210 @default.
- W2097059462 cites W2025743530 @default.
- W2097059462 cites W2026058763 @default.
- W2097059462 cites W2026428548 @default.
- W2097059462 cites W2026851739 @default.
- W2097059462 cites W2026866823 @default.
- W2097059462 cites W2029930661 @default.
- W2097059462 cites W2030148120 @default.
- W2097059462 cites W2031370326 @default.
- W2097059462 cites W2032667836 @default.
- W2097059462 cites W2035504341 @default.
- W2097059462 cites W2035653659 @default.
- W2097059462 cites W2035777338 @default.
- W2097059462 cites W2037374033 @default.
- W2097059462 cites W2037795068 @default.
- W2097059462 cites W2041673115 @default.
- W2097059462 cites W2042159165 @default.
- W2097059462 cites W2043486948 @default.
- W2097059462 cites W2043703101 @default.
- W2097059462 cites W2045716561 @default.
- W2097059462 cites W2048441028 @default.
- W2097059462 cites W2049714772 @default.
- W2097059462 cites W2050481191 @default.
- W2097059462 cites W2051282218 @default.
- W2097059462 cites W2051329702 @default.
- W2097059462 cites W2058278041 @default.
- W2097059462 cites W2060928333 @default.
- W2097059462 cites W2062909350 @default.
- W2097059462 cites W2063998127 @default.
- W2097059462 cites W2064751862 @default.
- W2097059462 cites W2065633653 @default.
- W2097059462 cites W2071341485 @default.
- W2097059462 cites W2071787763 @default.
- W2097059462 cites W2073619483 @default.
- W2097059462 cites W2079131261 @default.
- W2097059462 cites W2082401103 @default.
- W2097059462 cites W2082873063 @default.
- W2097059462 cites W2095277153 @default.
- W2097059462 cites W2099050012 @default.
- W2097059462 cites W2099494890 @default.
- W2097059462 cites W2100659741 @default.
- W2097059462 cites W2101410412 @default.
- W2097059462 cites W2101446591 @default.
- W2097059462 cites W2104602743 @default.
- W2097059462 cites W2106107897 @default.