Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097166266> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2097166266 endingPage "H981" @default.
- W2097166266 startingPage "H974" @default.
- W2097166266 abstract "Left ventricular function in volume overload hypertrophy is controversial. In humans, chronic severe volume overload eventually results in left ventricular dysfunction; paradoxically, experimental volume overload hypertrophy has nearly always been associated with normal left ventricular function. However, in most cases, experimental volume overload hypertrophy has either been mild or only present for a short duration. To help resolve the issue of contractile function in volume overload hypertrophy, we examined ventricular function in a recently described model of severe chronic experimental mitral regurgitation. Left ventricular function was measured before and 3 mo after the creation of severe mitral regurgitation (averaged regurgitant fraction 0.64 +/- 0.04). At 3 mo end-diastolic volume had increased from 78 +/- 5 to 114 +/- 7 ml (P less than 0.01). Significant left ventricular hypertrophy had occurred with an increase in the left ventricular weight-to-body weight ratio from 3.84 +/- 0.2 to 5.22 +/- 0.2 (P less than 0.01). All indicators of left ventricular function (ejection fraction, the end ejection stress-volume relationship, this relationship corrected for eccentric hypertrophy, and mean velocity of circumferential fiber shortening at a common stress) were reduced at 3 mo. Our study produced 64% volume overload which was maintained for 3 mo at which time there was a 36% increase in left ventricular mass. This amount of volume overload of this duration produced significant left ventricular dysfunction." @default.
- W2097166266 created "2016-06-24" @default.
- W2097166266 creator A5021422133 @default.
- W2097166266 creator A5028507295 @default.
- W2097166266 creator A5033451496 @default.
- W2097166266 creator A5044112361 @default.
- W2097166266 creator A5052709185 @default.
- W2097166266 date "1989-04-01" @default.
- W2097166266 modified "2023-10-18" @default.
- W2097166266 title "Left ventricular function in experimental volume overload hypertrophy" @default.
- W2097166266 doi "https://doi.org/10.1152/ajpheart.1989.256.4.h974" @default.
- W2097166266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2523200" @default.
- W2097166266 hasPublicationYear "1989" @default.
- W2097166266 type Work @default.
- W2097166266 sameAs 2097166266 @default.
- W2097166266 citedByCount "42" @default.
- W2097166266 countsByYear W20971662662014 @default.
- W2097166266 countsByYear W20971662662016 @default.
- W2097166266 countsByYear W20971662662017 @default.
- W2097166266 countsByYear W20971662662018 @default.
- W2097166266 countsByYear W20971662662019 @default.
- W2097166266 countsByYear W20971662662021 @default.
- W2097166266 countsByYear W20971662662023 @default.
- W2097166266 crossrefType "journal-article" @default.
- W2097166266 hasAuthorship W2097166266A5021422133 @default.
- W2097166266 hasAuthorship W2097166266A5028507295 @default.
- W2097166266 hasAuthorship W2097166266A5033451496 @default.
- W2097166266 hasAuthorship W2097166266A5044112361 @default.
- W2097166266 hasAuthorship W2097166266A5052709185 @default.
- W2097166266 hasConcept C121332964 @default.
- W2097166266 hasConcept C126322002 @default.
- W2097166266 hasConcept C164705383 @default.
- W2097166266 hasConcept C167414201 @default.
- W2097166266 hasConcept C20556612 @default.
- W2097166266 hasConcept C24595384 @default.
- W2097166266 hasConcept C2776002628 @default.
- W2097166266 hasConcept C2778198053 @default.
- W2097166266 hasConcept C2778271984 @default.
- W2097166266 hasConcept C2993373945 @default.
- W2097166266 hasConcept C3018791406 @default.
- W2097166266 hasConcept C62520636 @default.
- W2097166266 hasConcept C71924100 @default.
- W2097166266 hasConcept C78085059 @default.
- W2097166266 hasConcept C80461066 @default.
- W2097166266 hasConcept C84393581 @default.
- W2097166266 hasConceptScore W2097166266C121332964 @default.
- W2097166266 hasConceptScore W2097166266C126322002 @default.
- W2097166266 hasConceptScore W2097166266C164705383 @default.
- W2097166266 hasConceptScore W2097166266C167414201 @default.
- W2097166266 hasConceptScore W2097166266C20556612 @default.
- W2097166266 hasConceptScore W2097166266C24595384 @default.
- W2097166266 hasConceptScore W2097166266C2776002628 @default.
- W2097166266 hasConceptScore W2097166266C2778198053 @default.
- W2097166266 hasConceptScore W2097166266C2778271984 @default.
- W2097166266 hasConceptScore W2097166266C2993373945 @default.
- W2097166266 hasConceptScore W2097166266C3018791406 @default.
- W2097166266 hasConceptScore W2097166266C62520636 @default.
- W2097166266 hasConceptScore W2097166266C71924100 @default.
- W2097166266 hasConceptScore W2097166266C78085059 @default.
- W2097166266 hasConceptScore W2097166266C80461066 @default.
- W2097166266 hasConceptScore W2097166266C84393581 @default.
- W2097166266 hasIssue "4" @default.
- W2097166266 hasLocation W20971662661 @default.
- W2097166266 hasLocation W20971662662 @default.
- W2097166266 hasOpenAccess W2097166266 @default.
- W2097166266 hasPrimaryLocation W20971662661 @default.
- W2097166266 hasRelatedWork W1581001569 @default.
- W2097166266 hasRelatedWork W2038677584 @default.
- W2097166266 hasRelatedWork W2069462489 @default.
- W2097166266 hasRelatedWork W2095147394 @default.
- W2097166266 hasRelatedWork W2102967129 @default.
- W2097166266 hasRelatedWork W2125138303 @default.
- W2097166266 hasRelatedWork W2414113284 @default.
- W2097166266 hasRelatedWork W2747059585 @default.
- W2097166266 hasRelatedWork W2764849705 @default.
- W2097166266 hasRelatedWork W80464180 @default.
- W2097166266 hasVolume "256" @default.
- W2097166266 isParatext "false" @default.
- W2097166266 isRetracted "false" @default.
- W2097166266 magId "2097166266" @default.
- W2097166266 workType "article" @default.