FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097198780> ?p ?o ?g. }

• W2097198780 endingPage "2291" @default.
• W2097198780 startingPage "2277" @default.
• W2097198780 abstract "Abstract The house mouse is a well-established model organism, particularly for studying the genetics of complex traits. However, most studies of mice use classical inbred strains, whose genomes derive from multiple species. Relatively little is known about the distribution of genetic variation among these species or how variation among strains relates to variation in the wild. We sequenced intronic regions of five X-linked loci in large samples of wild Mus domesticus and M. musculus, and we found low levels of nucleotide diversity in both species. We compared these data to published data from short portions of six X-linked and 18 autosomal loci in wild mice. We estimate that M. domesticus and M. musculus diverged &lt;500,000 years ago. Consistent with this recent divergence, some gene genealogies were reciprocally monophyletic between these species, while others were paraphyletic or polyphyletic. In general, the X chromosome was more differentiated than the autosomes. We resequenced classical inbred strains for all 29 loci and found that inbred strains contain only a small amount of the genetic variation seen in wild mice. Notably, the X chromosome contains proportionately less variation among inbred strains than do the autosomes. Moreover, variation among inbred strains derives from differences between species as well as from differences within species, and these proportions differ in different genomic regions. Wild mice thus provide a reservoir of additional genetic variation that may be useful for mapping studies. Together these results suggest that wild mice will be a valuable complement to laboratory strains for studying the genetics of complex traits." @default.
• W2097198780 created "2016-06-24" @default.
• W2097198780 creator A5011500073 @default.
• W2097198780 creator A5072575293 @default.
• W2097198780 creator A5080739414 @default.
• W2097198780 date "2007-12-01" @default.
• W2097198780 modified "2023-10-12" @default.
• W2097198780 title "Nucleotide Variation in Wild and Inbred Mice" @default.
• W2097198780 cites W1670814307 @default.
• W2097198780 cites W1847545842 @default.
• W2097198780 cites W1871018719 @default.
• W2097198780 cites W1890991194 @default.
• W2097198780 cites W1896577830 @default.
• W2097198780 cites W1916336452 @default.
• W2097198780 cites W1928220195 @default.
• W2097198780 cites W1947714123 @default.
• W2097198780 cites W1971836750 @default.
• W2097198780 cites W1980936022 @default.
• W2097198780 cites W1989926019 @default.
• W2097198780 cites W2000134160 @default.
• W2097198780 cites W2008951726 @default.
• W2097198780 cites W2011154623 @default.
• W2097198780 cites W2022651039 @default.
• W2097198780 cites W2026702413 @default.
• W2097198780 cites W2041144702 @default.
• W2097198780 cites W2052756874 @default.
• W2097198780 cites W2054493687 @default.
• W2097198780 cites W2055711452 @default.
• W2097198780 cites W2057569762 @default.
• W2097198780 cites W2059061621 @default.
• W2097198780 cites W2060115431 @default.
• W2097198780 cites W2060384181 @default.
• W2097198780 cites W2064945973 @default.
• W2097198780 cites W2084689120 @default.
• W2097198780 cites W2085005709 @default.
• W2097198780 cites W2088561704 @default.
• W2097198780 cites W2096483686 @default.
• W2097198780 cites W2097606647 @default.
• W2097198780 cites W2098001529 @default.
• W2097198780 cites W2104743461 @default.
• W2097198780 cites W2107392618 @default.
• W2097198780 cites W2112704704 @default.
• W2097198780 cites W2113420705 @default.
• W2097198780 cites W2116652744 @default.
• W2097198780 cites W2120160630 @default.
• W2097198780 cites W2120666441 @default.
• W2097198780 cites W2123143346 @default.
• W2097198780 cites W2125275034 @default.
• W2097198780 cites W2126477661 @default.
• W2097198780 cites W2129588663 @default.
• W2097198780 cites W2132393729 @default.
• W2097198780 cites W2134705056 @default.
• W2097198780 cites W2135136237 @default.
• W2097198780 cites W2137845454 @default.
• W2097198780 cites W2140465281 @default.
• W2097198780 cites W2140784970 @default.
• W2097198780 cites W2140876173 @default.
• W2097198780 cites W2143220856 @default.
• W2097198780 cites W2145319723 @default.
• W2097198780 cites W2149318232 @default.
• W2097198780 cites W2151464048 @default.
• W2097198780 cites W2155286781 @default.
• W2097198780 cites W2157149092 @default.
• W2097198780 cites W2158785698 @default.
• W2097198780 cites W2161499761 @default.
• W2097198780 cites W2163502829 @default.
• W2097198780 cites W2163600007 @default.
• W2097198780 cites W2164202215 @default.
• W2097198780 cites W2164683872 @default.
• W2097198780 cites W2171963306 @default.
• W2097198780 cites W2332458435 @default.
• W2097198780 cites W4246910136 @default.
• W2097198780 doi "https://doi.org/10.1534/genetics.107.079988" @default.
• W2097198780 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2219490" @default.
• W2097198780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18073432" @default.
• W2097198780 hasPublicationYear "2007" @default.
• W2097198780 type Work @default.
• W2097198780 sameAs 2097198780 @default.
• W2097198780 citedByCount "94" @default.
• W2097198780 countsByYear W20971987802012 @default.
• W2097198780 countsByYear W20971987802013 @default.
• W2097198780 countsByYear W20971987802014 @default.
• W2097198780 countsByYear W20971987802015 @default.
• W2097198780 countsByYear W20971987802016 @default.
• W2097198780 countsByYear W20971987802017 @default.
• W2097198780 countsByYear W20971987802018 @default.
• W2097198780 countsByYear W20971987802019 @default.
• W2097198780 countsByYear W20971987802020 @default.
• W2097198780 countsByYear W20971987802021 @default.
• W2097198780 countsByYear W20971987802022 @default.
• W2097198780 countsByYear W20971987802023 @default.
• W2097198780 crossrefType "journal-article" @default.
• W2097198780 hasAuthorship W2097198780A5011500073 @default.
• W2097198780 hasAuthorship W2097198780A5072575293 @default.
• W2097198780 hasAuthorship W2097198780A5080739414 @default.
• W2097198780 hasBestOaLocation W20971987801 @default.
• W2097198780 hasConcept C104317684 @default.
• W2097198780 hasConcept C134925867 @default.

• next