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- W2097201441 abstract "Chalcones and their derivatives were synthesized and evaluated for their anti-inflammatory activity. In vitro, chalcones 2, 4, 8, 10 and 13 inhibited degranulation and 5-lipoxygenase in human neutrophils, whereas 11 behaved as scavenger of superoxide. Only four compounds (4-7) inhibited cyclo-oxygenase-2 activity. The majority of these samples showed anti-inflammatory effects in the mouse air pouch model." @default.
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- W2097201441 date "1998-05-01" @default.
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- W2097201441 title "Synthesis and anti-inflammatory activity of chalcone derivatives" @default.
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- W2097201441 doi "https://doi.org/10.1016/s0960-894x(98)00179-6" @default.
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