Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097202238> ?p ?o ?g. }
- W2097202238 endingPage "80" @default.
- W2097202238 startingPage "73" @default.
- W2097202238 abstract "Non-dystrophic myotonic syndromes represent a heterogeneous group of clinically quite similar diseases sharing the feature of myotonia. These syndromes can be separated into chloride and sodium channelopathies, with gene-defects in chloride or sodium channel proteins of the sarcolemmal membrane. Myotonia has its basis in an electrical instability of the sarcolemmal membrane. In the present study we examine the discriminative power of the resulting myotonic discharges for these disorders. Needle electromyography was performed by an electromyographer blinded for genetic diagnosis in 66 non-dystrophic myotonia patients (32 chloride and 34 sodium channelopathy). Five muscles in each patient were examined. Individual trains of myotonic discharges were extracted and analyzed with respect to firing characteristics. Myotonic discharge characteristics in the rectus femoris muscle almost perfectly discriminated chloride from sodium channelopathy patients. The first interdischarge interval as a single variable was longer than 30 ms in all but one of the chloride channelopathy patients and shorter than 30 ms in all of the sodium channelopathy patients. This resulted in a detection rate of over 95%. Myotonic discharges of a single muscle can be used to better guide toward a molecular diagnosis in non-dystrophic myotonic syndromes." @default.
- W2097202238 created "2016-06-24" @default.
- W2097202238 creator A5006878099 @default.
- W2097202238 creator A5007278895 @default.
- W2097202238 creator A5013956389 @default.
- W2097202238 creator A5015730866 @default.
- W2097202238 creator A5016306610 @default.
- W2097202238 creator A5023906844 @default.
- W2097202238 creator A5039642881 @default.
- W2097202238 creator A5061086955 @default.
- W2097202238 creator A5061622744 @default.
- W2097202238 creator A5072004949 @default.
- W2097202238 creator A5075906019 @default.
- W2097202238 creator A5081179915 @default.
- W2097202238 date "2015-01-01" @default.
- W2097202238 modified "2023-09-25" @default.
- W2097202238 title "Myotonic discharges discriminate chloride from sodium muscle channelopathies" @default.
- W2097202238 cites W1971526727 @default.
- W2097202238 cites W1986150601 @default.
- W2097202238 cites W1988222700 @default.
- W2097202238 cites W1992749849 @default.
- W2097202238 cites W2027780707 @default.
- W2097202238 cites W2031303249 @default.
- W2097202238 cites W2050420808 @default.
- W2097202238 cites W2055583449 @default.
- W2097202238 cites W2058038091 @default.
- W2097202238 cites W2061348213 @default.
- W2097202238 cites W2072091098 @default.
- W2097202238 cites W2092196545 @default.
- W2097202238 cites W2096311539 @default.
- W2097202238 cites W2096585760 @default.
- W2097202238 cites W2115458050 @default.
- W2097202238 cites W2135271579 @default.
- W2097202238 cites W2139244671 @default.
- W2097202238 cites W2423906748 @default.
- W2097202238 cites W3146600623 @default.
- W2097202238 cites W85835207 @default.
- W2097202238 doi "https://doi.org/10.1016/j.nmd.2014.09.014" @default.
- W2097202238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25454733" @default.
- W2097202238 hasPublicationYear "2015" @default.
- W2097202238 type Work @default.
- W2097202238 sameAs 2097202238 @default.
- W2097202238 citedByCount "7" @default.
- W2097202238 countsByYear W20972022382015 @default.
- W2097202238 countsByYear W20972022382019 @default.
- W2097202238 countsByYear W20972022382020 @default.
- W2097202238 crossrefType "journal-article" @default.
- W2097202238 hasAuthorship W2097202238A5006878099 @default.
- W2097202238 hasAuthorship W2097202238A5007278895 @default.
- W2097202238 hasAuthorship W2097202238A5013956389 @default.
- W2097202238 hasAuthorship W2097202238A5015730866 @default.
- W2097202238 hasAuthorship W2097202238A5016306610 @default.
- W2097202238 hasAuthorship W2097202238A5023906844 @default.
- W2097202238 hasAuthorship W2097202238A5039642881 @default.
- W2097202238 hasAuthorship W2097202238A5061086955 @default.
- W2097202238 hasAuthorship W2097202238A5061622744 @default.
- W2097202238 hasAuthorship W2097202238A5072004949 @default.
- W2097202238 hasAuthorship W2097202238A5075906019 @default.
- W2097202238 hasAuthorship W2097202238A5081179915 @default.
- W2097202238 hasConcept C126322002 @default.
- W2097202238 hasConcept C178790620 @default.
- W2097202238 hasConcept C185592680 @default.
- W2097202238 hasConcept C2776767690 @default.
- W2097202238 hasConcept C2777989426 @default.
- W2097202238 hasConcept C2778063965 @default.
- W2097202238 hasConcept C2780304057 @default.
- W2097202238 hasConcept C50952357 @default.
- W2097202238 hasConcept C537181965 @default.
- W2097202238 hasConcept C71924100 @default.
- W2097202238 hasConceptScore W2097202238C126322002 @default.
- W2097202238 hasConceptScore W2097202238C178790620 @default.
- W2097202238 hasConceptScore W2097202238C185592680 @default.
- W2097202238 hasConceptScore W2097202238C2776767690 @default.
- W2097202238 hasConceptScore W2097202238C2777989426 @default.
- W2097202238 hasConceptScore W2097202238C2778063965 @default.
- W2097202238 hasConceptScore W2097202238C2780304057 @default.
- W2097202238 hasConceptScore W2097202238C50952357 @default.
- W2097202238 hasConceptScore W2097202238C537181965 @default.
- W2097202238 hasConceptScore W2097202238C71924100 @default.
- W2097202238 hasIssue "1" @default.
- W2097202238 hasLocation W20972022381 @default.
- W2097202238 hasLocation W20972022382 @default.
- W2097202238 hasOpenAccess W2097202238 @default.
- W2097202238 hasPrimaryLocation W20972022381 @default.
- W2097202238 hasRelatedWork W1968160119 @default.
- W2097202238 hasRelatedWork W1971567084 @default.
- W2097202238 hasRelatedWork W2025958318 @default.
- W2097202238 hasRelatedWork W205360899 @default.
- W2097202238 hasRelatedWork W2092779985 @default.
- W2097202238 hasRelatedWork W2097202238 @default.
- W2097202238 hasRelatedWork W2115458050 @default.
- W2097202238 hasRelatedWork W2158424663 @default.
- W2097202238 hasRelatedWork W2397208834 @default.
- W2097202238 hasRelatedWork W2758244734 @default.
- W2097202238 hasVolume "25" @default.
- W2097202238 isParatext "false" @default.
- W2097202238 isRetracted "false" @default.
- W2097202238 magId "2097202238" @default.