Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097278399> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2097278399 endingPage "681" @default.
- W2097278399 startingPage "676" @default.
- W2097278399 abstract "Objective: To investigate the changes in cerebral oxygenation during coronary artery bypass grafting (CABG) with normothermic cardiopulmonary bypass (CPB) using near infrared spectroscopy. Methods: Measurement of cerebral cortical oxygenation changes included concentration of deoxygenated haemoglobin [HHb], oxygenated haemoglobin [O2Hb], changes in the redox status of the cytochrome c oxidase [Cyt-Ox], cerebral saturation as expressed by the tissue oxygenation index (TOI), and cerebral blood volume (CBV) as expressed by tissue haemoglobin index (THI). Measurements were performed in 19 consecutive patients undergoing normothermic (34–36 °C) CPB. Data were recorded at 0.5s intervals and averaged into 30 s epochs. Data analysis was carried at baseline, 1, 20, and 40 min after start of CPB, at rewarming, on weaning from CPB, and at closing of chest. Results: There were no in-hospital death, neurological deficits, or myocardial infarcts. Compared to baseline, during the entire CPB duration, there was a marked reduction in [O2Hb] and CBV which reached their worst level 40 min after initiation of CPB (from −3.03±5.1 to −9.25±7.20 μmol/l for [O2Hb], and a 24% reduction for CBV (both P≪0.0001)). The deterioration in [O2Hb] was recovered by the end of surgery, while the changes in CBV persisted. No significant changes occurred with respect to [HHb], [Cyt-Ox], and TOI. Conclusions: Conventional CABG is responsible for deterioration in [O2Hb], and CBV, which peak at 40–60 min following initiation of CPB. The changes in [O2Hb] are reversible whereas the reduction of CBV persists to the end of the surgery. This suggests a transient impairment in the autoregulatory mechanisms controlling cerebral blood flow following discontinuation of cardiopulmonary bypass." @default.
- W2097278399 created "2016-06-24" @default.
- W2097278399 creator A5021866525 @default.
- W2097278399 creator A5035327115 @default.
- W2097278399 creator A5052781376 @default.
- W2097278399 creator A5085664051 @default.
- W2097278399 date "2004-10-01" @default.
- W2097278399 modified "2023-10-16" @default.
- W2097278399 title "Effect of cardiopulmonary bypass on cortical cerebral oxygenation during coronary artery bypass grafting" @default.
- W2097278399 cites W163753897 @default.
- W2097278399 cites W1887566604 @default.
- W2097278399 cites W1991550546 @default.
- W2097278399 cites W2000249415 @default.
- W2097278399 cites W2002754600 @default.
- W2097278399 cites W2003363149 @default.
- W2097278399 cites W2006786570 @default.
- W2097278399 cites W2010215092 @default.
- W2097278399 cites W2011187311 @default.
- W2097278399 cites W2016213365 @default.
- W2097278399 cites W2033656714 @default.
- W2097278399 cites W2043260410 @default.
- W2097278399 cites W2046827694 @default.
- W2097278399 cites W2051455813 @default.
- W2097278399 cites W2061628772 @default.
- W2097278399 cites W2089266454 @default.
- W2097278399 cites W2089758120 @default.
- W2097278399 cites W2094061880 @default.
- W2097278399 cites W2118248854 @default.
- W2097278399 cites W2171848056 @default.
- W2097278399 cites W2402916591 @default.
- W2097278399 cites W2502447553 @default.
- W2097278399 doi "https://doi.org/10.1016/j.ejcts.2004.06.002" @default.
- W2097278399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15450556" @default.
- W2097278399 hasPublicationYear "2004" @default.
- W2097278399 type Work @default.
- W2097278399 sameAs 2097278399 @default.
- W2097278399 citedByCount "16" @default.
- W2097278399 countsByYear W20972783992012 @default.
- W2097278399 countsByYear W20972783992013 @default.
- W2097278399 countsByYear W20972783992017 @default.
- W2097278399 countsByYear W20972783992020 @default.
- W2097278399 countsByYear W20972783992021 @default.
- W2097278399 countsByYear W20972783992022 @default.
- W2097278399 crossrefType "journal-article" @default.
- W2097278399 hasAuthorship W2097278399A5021866525 @default.
- W2097278399 hasAuthorship W2097278399A5035327115 @default.
- W2097278399 hasAuthorship W2097278399A5052781376 @default.
- W2097278399 hasAuthorship W2097278399A5085664051 @default.
- W2097278399 hasBestOaLocation W20972783991 @default.
- W2097278399 hasConcept C126322002 @default.
- W2097278399 hasConcept C164705383 @default.
- W2097278399 hasConcept C2775841333 @default.
- W2097278399 hasConcept C2776820930 @default.
- W2097278399 hasConcept C2778881276 @default.
- W2097278399 hasConcept C42219234 @default.
- W2097278399 hasConcept C541997718 @default.
- W2097278399 hasConcept C70289976 @default.
- W2097278399 hasConcept C71924100 @default.
- W2097278399 hasConceptScore W2097278399C126322002 @default.
- W2097278399 hasConceptScore W2097278399C164705383 @default.
- W2097278399 hasConceptScore W2097278399C2775841333 @default.
- W2097278399 hasConceptScore W2097278399C2776820930 @default.
- W2097278399 hasConceptScore W2097278399C2778881276 @default.
- W2097278399 hasConceptScore W2097278399C42219234 @default.
- W2097278399 hasConceptScore W2097278399C541997718 @default.
- W2097278399 hasConceptScore W2097278399C70289976 @default.
- W2097278399 hasConceptScore W2097278399C71924100 @default.
- W2097278399 hasIssue "4" @default.
- W2097278399 hasLocation W20972783991 @default.
- W2097278399 hasLocation W20972783992 @default.
- W2097278399 hasOpenAccess W2097278399 @default.
- W2097278399 hasPrimaryLocation W20972783991 @default.
- W2097278399 hasRelatedWork W2016187818 @default.
- W2097278399 hasRelatedWork W2081755346 @default.
- W2097278399 hasRelatedWork W2271356446 @default.
- W2097278399 hasRelatedWork W2393078530 @default.
- W2097278399 hasRelatedWork W2400568189 @default.
- W2097278399 hasRelatedWork W2808919779 @default.
- W2097278399 hasRelatedWork W2912862887 @default.
- W2097278399 hasRelatedWork W4210486955 @default.
- W2097278399 hasRelatedWork W4210540426 @default.
- W2097278399 hasRelatedWork W2337520786 @default.
- W2097278399 hasVolume "26" @default.
- W2097278399 isParatext "false" @default.
- W2097278399 isRetracted "false" @default.
- W2097278399 magId "2097278399" @default.
- W2097278399 workType "article" @default.