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- W2097304844 abstract "We read with great interest the recent article by Fleischmann et al which reports a post hoc analysis of five rheumatoid arthritis (RA) randomised clinical trials (RCTs) to evaluate the correlation between Disease Activity Score in 28 joints calculated by using erythrocyte sedimentation rate (DAS28-ESR) or C reactive protein (DAS28-CRP).1 Since its introduction,2 DAS28-CRP has been used to evaluate clinical response in RCTs and daily practice by applying the same DAS28-ESR thresholds to define remission and low disease activity (LDA). Consistently with some previous reports,3–5 Fleischmann et al demonstrated that DAS28-CRP underestimates disease activity when using the same remission and LDA cut-off points validated for DAS28-ESR (2.6 and 3.2, respectively).6 Based on these findings, the authors suggested new thresholds for DAS28-CRP (2.4 for remission and 2.9 …" @default.
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- W2097304844 date "2014-10-10" @default.
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- W2097304844 title "Is there a need for new thresholds to define remission and low disease activity by Disease Activity Score 28 calculated with C reactive protein? Real life data from a local registry" @default.
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- W2097304844 doi "https://doi.org/10.1136/annrheumdis-2014-206651" @default.
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