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- W2097363670 abstract "The milk composition of high-yielding dairy cows is highly related to theirnutrition. The energy deficiency in dairy cows can causesubclinical or clinical ketosis. In ketotic state the concentration ofketone bodies (acetone, AC; acetoacetic acid, ACAC; and β -hydroxybutyric acid, BOHB) increases in the different body fluids andsimultaneously, changes in concentration of other compounds are also expected.The authors´hypothesis is that the members of the TCA-cycle, such as citric acid (CA)also change in association of increased formation of ketone body. Tosupport this hypothesis the concentrations of ketone body components and CAwere parallel measured and their relationship was studied in raw milksamples.Based on the AC concentration of the milk samples two groups were formedretrospectively: High Acetone (HA) Group ( n=41 ) of AC concentration >0.4 mMand Low Acetone (LA) Group ( n=78 ) with the AC level ≤ 0.4 mM.In all samples very low ACAC level was found, which is a consequence of thespontaneous decarboxylation of ACAC to AC during the usual sample storage.Focusing on the results of HA Group the authors found significantrelationship between CA and ketone bodies and a parallel drop of AC and CAduring the metabolically crucial first 1-4 weeks of lactation. For thisreason they suggest to introduce simple, easy, automated methods todetermine AC and/or CA concentration in raw milk." @default.
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- W2097363670 date "2003-12-01" @default.
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- W2097363670 title "CONCENTRATIONS OF CITRATE AND KETONE BODIES IN COW´S RAW MILK" @default.
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