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- W2097372228 abstract "PURPOSE: Hemorrhoids are a matter of concern due to a painful outcome. We describe a simple, easy and reliable experimental model to produce hemorrhoids in monkeys. METHODS: 14 monkeys (Cebus apella) were used. After general anesthesia, hemorrhoids were induced by ligation of the inferior hemorrhoidal vein, which is very alike to humans. The vein was located through a perianal incision, dissected and ligated with a 3-0 vicryl. The skin was sutured with a 4-0 catgut thread. Animals were kept in appropriate cages and evaluated daily. RESULTS: Nine days later there were hemorrhoidal piles in the anus in fifty percent (50%) of the animals. Outcome was unremarkable. There was no bleeding and all animals showed no signs of pain or suffering. CONCLUSION: This is an affordable and reliable experimental model to induce hemorrhoids for experimental studies." @default.
- W2097372228 created "2016-06-24" @default.
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- W2097372228 date "2006-10-01" @default.
- W2097372228 modified "2023-10-10" @default.
- W2097372228 title "Hemorrhoids: an experimental model in monkeys" @default.
- W2097372228 cites W1986204446 @default.
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- W2097372228 doi "https://doi.org/10.1590/s0102-86502006000500014" @default.
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