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- W2097398216 abstract "Background: Chag as’ disease causes dysphagia, regurgitation and retention of food in the esophageal body. Patients have longer pharyngeal clearance, which might be consequent of the involvement of the central nervous system or an adaptation to the esophageal transit impairment. If there is central nervous system involvement by the disease , we expect a larger difference in the oral and pharyngeal phases of swallowing between two consecutive swallows than that seen in controls. Our objective was to evaluate the difference of oral and pharyngeal transit duration between two consecutive swallows in patients with Chag as’ disease compared with controls. Methods: By videofluoroscopy, the duration of oral and pharyngeal transit, pharyngeal clearance, upper esophageal sphincter transit, hyoid movement and oropharyngeal transit was measured in 17 patients with Chag as’ disease and 15 asymptomatic volunteers. Each subject swallowed in duplicate and in sequence 5 mL and 10 mL of barium liquid and 5 mL and 10 mL of barium paste boluses. The differences were calculated between the two swallows of each volume and consistency in patients and controls. Results: There were no differences between controls and patients in the values of the differences between the two consecutive swallows, except for the hyoid movement duration of the 5 mL liquid bolus, causing a higher difference in controls than in patients. Conclusion : Oral and pharyngeal transit variation between two consecutive swallows is similar between patients with Chag as’ disease and controls, which suggests that the longer pharyngeal clearance duration previously described is not a consequence of impairment of the central nervous system control of swallowing. doi: http://dx.doi.org/10.4021/gr574w" @default.
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- W2097398216 date "2013-01-01" @default.
- W2097398216 modified "2023-09-26" @default.
- W2097398216 title "Variability of Oral and Pharyngeal Transit Between Two Consecutive Swallows in Chagas’ Disease" @default.
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- W2097398216 doi "https://doi.org/10.4021/gr574w" @default.
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