FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097413574> ?p ?o ?g. }

• W2097413574 abstract "A number of molecular alterations have been described for melanoma. Melanomas with BRAF mutations tend to be located in areas of intermittent sun exposure, whereas melanomas with KIT mutations mostly appear in acral areas, the mucosas, and areas of chronic sun exposure. Sorafenib, a BRAF inhibitor, has a cytostatic effect on most melanomas with mutations affecting the mitogen-activated protein kinase (MAPK) pathway, and is also capable of triggering apoptosis in a small subgroup of these melanomas. By inhibiting KIT, imatinib has a cytostatic and cytotoxic effect on melanomas with KIT mutations, and probably has the same effect on another subgroup of melanomas with other as yet imperfectly understood KIT mutations. For therapy to be effective, agents should be selected according to the pathways associated with the genetic mutations present in the melanoma." @default.
• W2097413574 created "2016-06-24" @default.
• W2097413574 creator A5014405680 @default.
• W2097413574 creator A5044267312 @default.
• W2097413574 date "2010-01-01" @default.
• W2097413574 modified "2023-09-25" @default.
• W2097413574 title "New Therapies Targeting the Genetic Mutations Responsible for Different Types of Melanoma" @default.
• W2097413574 cites W1951046932 @default.
• W2097413574 cites W1980016709 @default.
• W2097413574 cites W1986538148 @default.
• W2097413574 cites W1989121777 @default.
• W2097413574 cites W1993336164 @default.
• W2097413574 cites W1994376203 @default.
• W2097413574 cites W2000292189 @default.
• W2097413574 cites W2006808266 @default.
• W2097413574 cites W2014206073 @default.
• W2097413574 cites W2015682571 @default.
• W2097413574 cites W2018110839 @default.
• W2097413574 cites W2019496774 @default.
• W2097413574 cites W2019950585 @default.
• W2097413574 cites W2022261774 @default.
• W2097413574 cites W2032751670 @default.
• W2097413574 cites W2034048944 @default.
• W2097413574 cites W2041098455 @default.
• W2097413574 cites W2048672579 @default.
• W2097413574 cites W2060317877 @default.
• W2097413574 cites W2060573548 @default.
• W2097413574 cites W2070204715 @default.
• W2097413574 cites W2077246243 @default.
• W2097413574 cites W2079641245 @default.
• W2097413574 cites W2095034382 @default.
• W2097413574 cites W2106726562 @default.
• W2097413574 cites W2121735065 @default.
• W2097413574 cites W2124662474 @default.
• W2097413574 cites W2125037724 @default.
• W2097413574 cites W2129683402 @default.
• W2097413574 cites W2131819768 @default.
• W2097413574 cites W2137705897 @default.
• W2097413574 cites W2139684524 @default.
• W2097413574 cites W2150740687 @default.
• W2097413574 cites W2151507583 @default.
• W2097413574 cites W2155299791 @default.
• W2097413574 cites W2156266404 @default.
• W2097413574 cites W2160378889 @default.
• W2097413574 cites W2161275429 @default.
• W2097413574 cites W2161810908 @default.
• W2097413574 cites W2167039800 @default.
• W2097413574 cites W2168029948 @default.
• W2097413574 cites W2243099628 @default.
• W2097413574 doi "https://doi.org/10.1016/s1578-2190(10)70661-2" @default.
• W2097413574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20525481" @default.
• W2097413574 hasPublicationYear "2010" @default.
• W2097413574 type Work @default.
• W2097413574 sameAs 2097413574 @default.
• W2097413574 citedByCount "1" @default.
• W2097413574 countsByYear W20974135742013 @default.
• W2097413574 crossrefType "journal-article" @default.
• W2097413574 hasAuthorship W2097413574A5014405680 @default.
• W2097413574 hasAuthorship W2097413574A5044267312 @default.
• W2097413574 hasBestOaLocation W20974135741 @default.
• W2097413574 hasConcept C104317684 @default.
• W2097413574 hasConcept C121608353 @default.
• W2097413574 hasConcept C184235292 @default.
• W2097413574 hasConcept C2777583451 @default.
• W2097413574 hasConcept C2777658100 @default.
• W2097413574 hasConcept C2778019345 @default.
• W2097413574 hasConcept C2778695046 @default.
• W2097413574 hasConcept C2778729363 @default.
• W2097413574 hasConcept C2781230642 @default.
• W2097413574 hasConcept C2781249067 @default.
• W2097413574 hasConcept C501734568 @default.
• W2097413574 hasConcept C502942594 @default.
• W2097413574 hasConcept C54355233 @default.
• W2097413574 hasConcept C57074206 @default.
• W2097413574 hasConcept C71924100 @default.
• W2097413574 hasConcept C86803240 @default.
• W2097413574 hasConceptScore W2097413574C104317684 @default.
• W2097413574 hasConceptScore W2097413574C121608353 @default.
• W2097413574 hasConceptScore W2097413574C184235292 @default.
• W2097413574 hasConceptScore W2097413574C2777583451 @default.
• W2097413574 hasConceptScore W2097413574C2777658100 @default.
• W2097413574 hasConceptScore W2097413574C2778019345 @default.
• W2097413574 hasConceptScore W2097413574C2778695046 @default.
• W2097413574 hasConceptScore W2097413574C2778729363 @default.
• W2097413574 hasConceptScore W2097413574C2781230642 @default.
• W2097413574 hasConceptScore W2097413574C2781249067 @default.
• W2097413574 hasConceptScore W2097413574C501734568 @default.
• W2097413574 hasConceptScore W2097413574C502942594 @default.
• W2097413574 hasConceptScore W2097413574C54355233 @default.
• W2097413574 hasConceptScore W2097413574C57074206 @default.
• W2097413574 hasConceptScore W2097413574C71924100 @default.
• W2097413574 hasConceptScore W2097413574C86803240 @default.
• W2097413574 hasLocation W20974135741 @default.
• W2097413574 hasLocation W20974135742 @default.
• W2097413574 hasOpenAccess W2097413574 @default.
• W2097413574 hasPrimaryLocation W20974135741 @default.
• W2097413574 hasRelatedWork W1561872430 @default.
• W2097413574 hasRelatedWork W2034934174 @default.
• W2097413574 hasRelatedWork W2063871886 @default.
• W2097413574 hasRelatedWork W2126194784 @default.

• next