FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097425158> ?p ?o ?g. }

• W2097425158 endingPage "853" @default.
• W2097425158 startingPage "841" @default.
• W2097425158 abstract "Porphyromonas gingivalis , an obligately anaerobic bacterium, is implicated as a major pathogen in the development and progression of chronic periodontitis. Although expression of several virulence factors of the bacterium has been found to be affected by environmental stress such as entrance into the stationary growth phase and heat, there is relatively little information on the mechanisms that may operate in the bacterium in response to environmental stress. In this study, a novel protein (UstA) was investigated that was initially identified following two-dimensional gel analysis. Expression of UstA was upregulated in stationary phase or by exposure to atmospheric oxygen. N-terminal sequencing and database analysis with the P. gingivalis genome sequence revealed that the UstA-encoding gene ( ustA ) was located upstream of a homologue of the usp gene encoding the universal stress protein on the chromosome. The ustA gene appeared to be transcribed in a monocistronic fashion, as revealed by primer extension and Northern blot analysis. To elucidate the role of UstA in the bacterium, chromosomal mutants carrying a disruption of the ustA gene were constructed. The ustA mutant grew slower than the wild-type parent strain in rich medium, resulting in a lower yield in stationary phase. Furthermore, in this mutant, expression levels of the P. gingivalis homologues of superoxide dismutase, thiol peroxidase and thioredoxin were markedly higher than those in the wild-type, especially in stationary phase. The ustA mutant was more resistant to diamide, a thiol-specific oxidant, than the wild-type. In addition, the ustA mutation suppressed hypersensitivities of the oxyR mutant to diamide, metronidazole and mitomycin C. These results suggest that UstA may play a significant role in oxidative stress responses in the bacterium." @default.
• W2097425158 created "2016-06-24" @default.
• W2097425158 creator A5001716964 @default.
• W2097425158 creator A5014597030 @default.
• W2097425158 creator A5036114663 @default.
• W2097425158 creator A5038527750 @default.
• W2097425158 creator A5050313091 @default.
• W2097425158 creator A5051142412 @default.
• W2097425158 creator A5059184154 @default.
• W2097425158 creator A5061498278 @default.
• W2097425158 creator A5076302608 @default.
• W2097425158 date "2005-03-01" @default.
• W2097425158 modified "2023-10-03" @default.
• W2097425158 title "Novel stationary-phase-upregulated protein of Porphyromonas gingivalis influences production of superoxide dismutase, thiol peroxidase and thioredoxin" @default.
• W2097425158 cites W1541034324 @default.
• W2097425158 cites W1553988965 @default.
• W2097425158 cites W1560041901 @default.
• W2097425158 cites W1580909913 @default.
• W2097425158 cites W1918519520 @default.
• W2097425158 cites W1932052686 @default.
• W2097425158 cites W1940436875 @default.
• W2097425158 cites W1973954044 @default.
• W2097425158 cites W1984789394 @default.
• W2097425158 cites W1985165153 @default.
• W2097425158 cites W2009353883 @default.
• W2097425158 cites W2015095310 @default.
• W2097425158 cites W2020054502 @default.
• W2097425158 cites W2035735673 @default.
• W2097425158 cites W2042045767 @default.
• W2097425158 cites W2044906864 @default.
• W2097425158 cites W2056077453 @default.
• W2097425158 cites W2061436865 @default.
• W2097425158 cites W2062916685 @default.
• W2097425158 cites W2064000861 @default.
• W2097425158 cites W2072792818 @default.
• W2097425158 cites W2079899518 @default.
• W2097425158 cites W2080437762 @default.
• W2097425158 cites W2086009543 @default.
• W2097425158 cites W2086814349 @default.
• W2097425158 cites W2087324903 @default.
• W2097425158 cites W2089609186 @default.
• W2097425158 cites W2118443091 @default.
• W2097425158 cites W2119398366 @default.
• W2097425158 cites W2123053149 @default.
• W2097425158 cites W2126990225 @default.
• W2097425158 cites W2133664523 @default.
• W2097425158 cites W2142507656 @default.
• W2097425158 cites W2149770337 @default.
• W2097425158 cites W2150382136 @default.
• W2097425158 cites W2156478713 @default.
• W2097425158 cites W2156806286 @default.
• W2097425158 cites W2160900063 @default.
• W2097425158 cites W2166881415 @default.
• W2097425158 cites W4245276795 @default.
• W2097425158 doi "https://doi.org/10.1099/mic.0.27589-0" @default.
• W2097425158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15758230" @default.
• W2097425158 hasPublicationYear "2005" @default.
• W2097425158 type Work @default.
• W2097425158 sameAs 2097425158 @default.
• W2097425158 citedByCount "27" @default.
• W2097425158 countsByYear W20974251582012 @default.
• W2097425158 countsByYear W20974251582014 @default.
• W2097425158 countsByYear W20974251582016 @default.
• W2097425158 countsByYear W20974251582017 @default.
• W2097425158 countsByYear W20974251582018 @default.
• W2097425158 countsByYear W20974251582019 @default.
• W2097425158 countsByYear W20974251582020 @default.
• W2097425158 countsByYear W20974251582021 @default.
• W2097425158 crossrefType "journal-article" @default.
• W2097425158 hasAuthorship W2097425158A5001716964 @default.
• W2097425158 hasAuthorship W2097425158A5014597030 @default.
• W2097425158 hasAuthorship W2097425158A5036114663 @default.
• W2097425158 hasAuthorship W2097425158A5038527750 @default.
• W2097425158 hasAuthorship W2097425158A5050313091 @default.
• W2097425158 hasAuthorship W2097425158A5051142412 @default.
• W2097425158 hasAuthorship W2097425158A5059184154 @default.
• W2097425158 hasAuthorship W2097425158A5061498278 @default.
• W2097425158 hasAuthorship W2097425158A5076302608 @default.
• W2097425158 hasBestOaLocation W20974251581 @default.
• W2097425158 hasConcept C104317684 @default.
• W2097425158 hasConcept C143065580 @default.
• W2097425158 hasConcept C153911025 @default.
• W2097425158 hasConcept C2775838275 @default.
• W2097425158 hasConcept C2776151105 @default.
• W2097425158 hasConcept C2780183776 @default.
• W2097425158 hasConcept C3623737 @default.
• W2097425158 hasConcept C523546767 @default.
• W2097425158 hasConcept C54355233 @default.
• W2097425158 hasConcept C55493867 @default.
• W2097425158 hasConcept C86803240 @default.
• W2097425158 hasConcept C89423630 @default.
• W2097425158 hasConceptScore W2097425158C104317684 @default.
• W2097425158 hasConceptScore W2097425158C143065580 @default.
• W2097425158 hasConceptScore W2097425158C153911025 @default.
• W2097425158 hasConceptScore W2097425158C2775838275 @default.
• W2097425158 hasConceptScore W2097425158C2776151105 @default.
• W2097425158 hasConceptScore W2097425158C2780183776 @default.
• W2097425158 hasConceptScore W2097425158C3623737 @default.

• next