Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097443249> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2097443249 endingPage "148" @default.
- W2097443249 startingPage "142" @default.
- W2097443249 abstract "To examine the impact of time to thrombolytic treatment on multiple acute outcome variables in a single trial of thrombolysis in acute myocardial infarction.Mortality and reinfarction rate were measured in 2770 patients with acute myocardial infarction who received thrombolysis within 12 hours in CORE, an international, dose ranging trial of poloxamer 188. Tc-99m sestamibi infarct size and radionuclide angiographic ejection fraction substudies included 1099 and 1074 patients, respectively.Time to thrombolysis, subgrouped by intervals (< 2, 2-4, > or = 4-6, and > or = 6 hours), was significantly associated with infarct size (median 15.0%, 18.5%, 22.0%, 18.5% of left ventricle; p = 0.033), mean (SD) ejection fraction (51.5 (12.0)%, 48. 3 (13.9)%, 48.2 (13.3)%, 48.2 (15.0)%; p = 0.006), 35 day mortality (5.7%, 7.1%, 7.9%, 12.5%; p = 0.0004), six month mortality (7.3%, 8. 6%, 10.4%, 15.5%; p < 0.0001), and 35 day reinfarction rate (6.1%, 3. 2%, 4.0%, 0.9%; p = 0.0001).In this single large trial, the beneficial effect of time to thrombolysis on infarct size and ejection fraction was restricted to treatment given within two hours of symptom onset, while the effect on mortality was evident over all time intervals. Reinfarction rate was higher in patients treated with earlier thrombolysis." @default.
- W2097443249 created "2016-06-24" @default.
- W2097443249 creator A5024726160 @default.
- W2097443249 date "2000-08-01" @default.
- W2097443249 modified "2023-10-14" @default.
- W2097443249 title "The impact of time to thrombolytic treatment on outcome in patients with acute myocardial infarction" @default.
- W2097443249 cites W1491100040 @default.
- W2097443249 cites W183841710 @default.
- W2097443249 cites W1924409040 @default.
- W2097443249 cites W1968216213 @default.
- W2097443249 cites W1971587698 @default.
- W2097443249 cites W1972640155 @default.
- W2097443249 cites W1976122990 @default.
- W2097443249 cites W1978850094 @default.
- W2097443249 cites W1986940955 @default.
- W2097443249 cites W1989147130 @default.
- W2097443249 cites W1998685777 @default.
- W2097443249 cites W2004941049 @default.
- W2097443249 cites W2010718453 @default.
- W2097443249 cites W2016233351 @default.
- W2097443249 cites W2023663380 @default.
- W2097443249 cites W2028208331 @default.
- W2097443249 cites W2029351753 @default.
- W2097443249 cites W2035981171 @default.
- W2097443249 cites W2036362960 @default.
- W2097443249 cites W2056731242 @default.
- W2097443249 cites W2069371112 @default.
- W2097443249 cites W2080909257 @default.
- W2097443249 cites W2081952076 @default.
- W2097443249 cites W2129805832 @default.
- W2097443249 cites W2152388592 @default.
- W2097443249 cites W2157749338 @default.
- W2097443249 cites W2164319587 @default.
- W2097443249 cites W2165215018 @default.
- W2097443249 cites W2252777310 @default.
- W2097443249 cites W2318123143 @default.
- W2097443249 cites W3021438309 @default.
- W2097443249 doi "https://doi.org/10.1136/heart.84.2.142" @default.
- W2097443249 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1760917" @default.
- W2097443249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10908248" @default.
- W2097443249 hasPublicationYear "2000" @default.
- W2097443249 type Work @default.
- W2097443249 sameAs 2097443249 @default.
- W2097443249 citedByCount "56" @default.
- W2097443249 countsByYear W20974432492012 @default.
- W2097443249 countsByYear W20974432492013 @default.
- W2097443249 countsByYear W20974432492014 @default.
- W2097443249 countsByYear W20974432492015 @default.
- W2097443249 countsByYear W20974432492016 @default.
- W2097443249 countsByYear W20974432492017 @default.
- W2097443249 countsByYear W20974432492018 @default.
- W2097443249 countsByYear W20974432492019 @default.
- W2097443249 countsByYear W20974432492022 @default.
- W2097443249 crossrefType "journal-article" @default.
- W2097443249 hasAuthorship W2097443249A5024726160 @default.
- W2097443249 hasBestOaLocation W20974432491 @default.
- W2097443249 hasConcept C126322002 @default.
- W2097443249 hasConcept C164705383 @default.
- W2097443249 hasConcept C179755657 @default.
- W2097443249 hasConcept C2777798775 @default.
- W2097443249 hasConcept C2778198053 @default.
- W2097443249 hasConcept C2778921608 @default.
- W2097443249 hasConcept C2779581417 @default.
- W2097443249 hasConcept C500558357 @default.
- W2097443249 hasConcept C71924100 @default.
- W2097443249 hasConcept C78085059 @default.
- W2097443249 hasConceptScore W2097443249C126322002 @default.
- W2097443249 hasConceptScore W2097443249C164705383 @default.
- W2097443249 hasConceptScore W2097443249C179755657 @default.
- W2097443249 hasConceptScore W2097443249C2777798775 @default.
- W2097443249 hasConceptScore W2097443249C2778198053 @default.
- W2097443249 hasConceptScore W2097443249C2778921608 @default.
- W2097443249 hasConceptScore W2097443249C2779581417 @default.
- W2097443249 hasConceptScore W2097443249C500558357 @default.
- W2097443249 hasConceptScore W2097443249C71924100 @default.
- W2097443249 hasConceptScore W2097443249C78085059 @default.
- W2097443249 hasIssue "2" @default.
- W2097443249 hasLocation W20974432491 @default.
- W2097443249 hasLocation W20974432492 @default.
- W2097443249 hasLocation W20974432493 @default.
- W2097443249 hasLocation W20974432494 @default.
- W2097443249 hasOpenAccess W2097443249 @default.
- W2097443249 hasPrimaryLocation W20974432491 @default.
- W2097443249 hasRelatedWork W1989098122 @default.
- W2097443249 hasRelatedWork W2200979148 @default.
- W2097443249 hasRelatedWork W2353626795 @default.
- W2097443249 hasRelatedWork W2355365047 @default.
- W2097443249 hasRelatedWork W2356933042 @default.
- W2097443249 hasRelatedWork W2389271213 @default.
- W2097443249 hasRelatedWork W2412249724 @default.
- W2097443249 hasRelatedWork W2899951469 @default.
- W2097443249 hasRelatedWork W2911722796 @default.
- W2097443249 hasRelatedWork W2996846122 @default.
- W2097443249 hasVolume "84" @default.
- W2097443249 isParatext "false" @default.
- W2097443249 isRetracted "false" @default.
- W2097443249 magId "2097443249" @default.
- W2097443249 workType "article" @default.