Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097444820> ?p ?o ?g. }
- W2097444820 endingPage "433" @default.
- W2097444820 startingPage "425" @default.
- W2097444820 abstract "PSP94 (beta microseminoprotein, beta MSP) is one of the three major proteins secreted by the normal human prostate gland. Using reverse transcriptase polymerase chain reaction (RT-PCR) and Southern blotting, PSP94 transcripts were shown in human endometrium, myometrium, ovary, breast, placenta and in the human endometrial cancer cell lines KLE and AN3 CA. Primers used in these studies were specific for human prostate PSP94, and were derived from its flanking non-coding regions. The results were confirmed by sequence analysis of two independently derived clones from normal human breast tissues and the other two from KLE cells respectively. The sequences were identical with the coding sequence of human prostate PSP94 cDNA. Using RNA from the endometrial tissues, two different transcripts of approximately 487 bp, equivalent to prostate PSP94 and approximately 381 bp, corresponding to prostate PSP57, its alternately spliced form, were amplified by RT-PCR. Human ovary, breast, placenta and endometrial cancer cell lines (KLE, AN3 CA), however, showed only the full length, approximately 487 bp, PSP94 transcript. We further demonstrated by in situ hybridization that PSP94 mRNA is expressed specifically in the glandular epithelial cells, and not in the stroma of both the human endometrial and breast tissues. Further, using image analysis of in situ hybridization data, the levels of PSP94 mRNA in the cycling endometrial tissues and in breast confirmed the differential levels of expression in the cycling endometrium (P<0.005). This study distinctly demonstrated significant expression of PSP94 mRNA in human uterine, breast and other female reproductive tissues as well in the endometrial cancer cell lines, suggesting that it may have a role in these tissues as a local autocrine paracrine factor." @default.
- W2097444820 created "2016-06-24" @default.
- W2097444820 creator A5013048325 @default.
- W2097444820 creator A5014252085 @default.
- W2097444820 creator A5017010710 @default.
- W2097444820 creator A5040813583 @default.
- W2097444820 creator A5044803843 @default.
- W2097444820 date "2000-05-01" @default.
- W2097444820 modified "2023-09-25" @default.
- W2097444820 title "Prostatic secretory protein (PSP94) expression in human female reproductive tissues, breast and in endometrial cancer cell lines" @default.
- W2097444820 cites W1547848827 @default.
- W2097444820 cites W1976137755 @default.
- W2097444820 cites W1979693703 @default.
- W2097444820 cites W1980633528 @default.
- W2097444820 cites W1985772879 @default.
- W2097444820 cites W1990989603 @default.
- W2097444820 cites W2004182213 @default.
- W2097444820 cites W2008458243 @default.
- W2097444820 cites W2010461405 @default.
- W2097444820 cites W2011766374 @default.
- W2097444820 cites W2013713901 @default.
- W2097444820 cites W2021017012 @default.
- W2097444820 cites W2033134548 @default.
- W2097444820 cites W2056486024 @default.
- W2097444820 cites W2062969895 @default.
- W2097444820 cites W2071976666 @default.
- W2097444820 cites W2072901256 @default.
- W2097444820 cites W2073579996 @default.
- W2097444820 cites W2074174652 @default.
- W2097444820 cites W2086472648 @default.
- W2097444820 cites W2091206794 @default.
- W2097444820 cites W2092819628 @default.
- W2097444820 cites W2114539860 @default.
- W2097444820 cites W2130001973 @default.
- W2097444820 cites W2144634347 @default.
- W2097444820 cites W2153549502 @default.
- W2097444820 cites W2344251959 @default.
- W2097444820 cites W2418075375 @default.
- W2097444820 cites W67612623 @default.
- W2097444820 doi "https://doi.org/10.1677/joe.0.1650425" @default.
- W2097444820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10810306" @default.
- W2097444820 hasPublicationYear "2000" @default.
- W2097444820 type Work @default.
- W2097444820 sameAs 2097444820 @default.
- W2097444820 citedByCount "28" @default.
- W2097444820 countsByYear W20974448202013 @default.
- W2097444820 countsByYear W20974448202014 @default.
- W2097444820 countsByYear W20974448202015 @default.
- W2097444820 countsByYear W20974448202018 @default.
- W2097444820 countsByYear W20974448202020 @default.
- W2097444820 countsByYear W20974448202021 @default.
- W2097444820 crossrefType "journal-article" @default.
- W2097444820 hasAuthorship W2097444820A5013048325 @default.
- W2097444820 hasAuthorship W2097444820A5014252085 @default.
- W2097444820 hasAuthorship W2097444820A5017010710 @default.
- W2097444820 hasAuthorship W2097444820A5040813583 @default.
- W2097444820 hasAuthorship W2097444820A5044803843 @default.
- W2097444820 hasBestOaLocation W20974448201 @default.
- W2097444820 hasConcept C104317684 @default.
- W2097444820 hasConcept C105580179 @default.
- W2097444820 hasConcept C121608353 @default.
- W2097444820 hasConcept C126322002 @default.
- W2097444820 hasConcept C134018914 @default.
- W2097444820 hasConcept C153911025 @default.
- W2097444820 hasConcept C177707886 @default.
- W2097444820 hasConcept C2776235491 @default.
- W2097444820 hasConcept C2779742232 @default.
- W2097444820 hasConcept C54355233 @default.
- W2097444820 hasConcept C71924100 @default.
- W2097444820 hasConcept C81439078 @default.
- W2097444820 hasConcept C86803240 @default.
- W2097444820 hasConceptScore W2097444820C104317684 @default.
- W2097444820 hasConceptScore W2097444820C105580179 @default.
- W2097444820 hasConceptScore W2097444820C121608353 @default.
- W2097444820 hasConceptScore W2097444820C126322002 @default.
- W2097444820 hasConceptScore W2097444820C134018914 @default.
- W2097444820 hasConceptScore W2097444820C153911025 @default.
- W2097444820 hasConceptScore W2097444820C177707886 @default.
- W2097444820 hasConceptScore W2097444820C2776235491 @default.
- W2097444820 hasConceptScore W2097444820C2779742232 @default.
- W2097444820 hasConceptScore W2097444820C54355233 @default.
- W2097444820 hasConceptScore W2097444820C71924100 @default.
- W2097444820 hasConceptScore W2097444820C81439078 @default.
- W2097444820 hasConceptScore W2097444820C86803240 @default.
- W2097444820 hasIssue "2" @default.
- W2097444820 hasLocation W20974448201 @default.
- W2097444820 hasLocation W20974448202 @default.
- W2097444820 hasOpenAccess W2097444820 @default.
- W2097444820 hasPrimaryLocation W20974448201 @default.
- W2097444820 hasRelatedWork W1500814995 @default.
- W2097444820 hasRelatedWork W1515471646 @default.
- W2097444820 hasRelatedWork W1975928965 @default.
- W2097444820 hasRelatedWork W1980194808 @default.
- W2097444820 hasRelatedWork W2030540411 @default.
- W2097444820 hasRelatedWork W2044918899 @default.
- W2097444820 hasRelatedWork W2081084759 @default.
- W2097444820 hasRelatedWork W2122076186 @default.
- W2097444820 hasRelatedWork W2133612430 @default.