Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097479849> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2097479849 endingPage "819" @default.
- W2097479849 startingPage "813" @default.
- W2097479849 abstract "Invasive fungal infections (IFI) are associated with high mortality in liver transplant recipients. Prevention remains an elusive goal, especially for IFI caused by moulds.From January 1998, patients who fulfilled four or more variables identified as risk factors for IFI received a cumulative dose of 1-1.5 g of lipid formulations of amphotericin B (L-AmpB; AmBisome or Abelcet). The development of IFI in these patients was compared with historical patients.Two hundred and eighty liver transplant recipients were analysed over a period of 8 years. In the historical group, IFI were observed in 22 of 131 patients (17%) and invasive aspergillosis in 13 of them (10%). After January 1998, IFI were observed in nine of 149 (6%) (P < 0.01) and invasive aspergillosis in six patients (4%) (P = 0.08). In patients with four or more risk factors (high risk) for IFI, the administration of L-AmpB reduced the risk from 36% to 14% (P = 0.07), and the risk of aspergillosis from 23% to 5% (P = 0.08). Notably, prophylaxis reduced the risk of aspergillosis from 32% to 0% in dialysed patients (P = 0.03). Variables independently associated with IFI in high-risk patients were dialysis [odds ratio (OR) 3.9; 95% confidence interval (CI) 1-16.7] and surgical reintervention (OR 5.4; 95% CI 1.2-24.6), while L-AmpB was a protective factor in this multivariate analysis (OR 0.1; 95% CI 0.02-0.8). The analysis in these high-risk patients was not able to demonstrate an association between the administration of L-AmpB and higher survival.Selected risk factors are good predictors of IFI in liver transplant recipients. The administration of L-AmpB in high-risk patients is independently associated with a reduction of IFI." @default.
- W2097479849 created "2016-06-24" @default.
- W2097479849 creator A5009198871 @default.
- W2097479849 date "2003-09-30" @default.
- W2097479849 modified "2023-09-27" @default.
- W2097479849 title "Prevention of invasive fungal infections in liver transplant recipients: the role of prophylaxis with lipid formulations of amphotericin B in high-risk patients" @default.
- W2097479849 cites W1964791233 @default.
- W2097479849 cites W1975997437 @default.
- W2097479849 cites W1978379678 @default.
- W2097479849 cites W1995337263 @default.
- W2097479849 cites W1997018272 @default.
- W2097479849 cites W2012489974 @default.
- W2097479849 cites W2013621399 @default.
- W2097479849 cites W2047526581 @default.
- W2097479849 cites W2061748969 @default.
- W2097479849 cites W2077497174 @default.
- W2097479849 cites W2083330927 @default.
- W2097479849 cites W2083506768 @default.
- W2097479849 cites W2084770271 @default.
- W2097479849 cites W2121418407 @default.
- W2097479849 cites W2133333746 @default.
- W2097479849 cites W2150183740 @default.
- W2097479849 cites W2171217133 @default.
- W2097479849 doi "https://doi.org/10.1093/jac/dkg450" @default.
- W2097479849 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14563893" @default.
- W2097479849 hasPublicationYear "2003" @default.
- W2097479849 type Work @default.
- W2097479849 sameAs 2097479849 @default.
- W2097479849 citedByCount "101" @default.
- W2097479849 countsByYear W20974798492012 @default.
- W2097479849 countsByYear W20974798492013 @default.
- W2097479849 countsByYear W20974798492014 @default.
- W2097479849 countsByYear W20974798492015 @default.
- W2097479849 countsByYear W20974798492016 @default.
- W2097479849 countsByYear W20974798492017 @default.
- W2097479849 countsByYear W20974798492018 @default.
- W2097479849 countsByYear W20974798492019 @default.
- W2097479849 countsByYear W20974798492020 @default.
- W2097479849 countsByYear W20974798492021 @default.
- W2097479849 countsByYear W20974798492022 @default.
- W2097479849 countsByYear W20974798492023 @default.
- W2097479849 crossrefType "journal-article" @default.
- W2097479849 hasAuthorship W2097479849A5009198871 @default.
- W2097479849 hasBestOaLocation W20974798491 @default.
- W2097479849 hasConcept C126322002 @default.
- W2097479849 hasConcept C141071460 @default.
- W2097479849 hasConcept C156957248 @default.
- W2097479849 hasConcept C16005928 @default.
- W2097479849 hasConcept C203014093 @default.
- W2097479849 hasConcept C2776391196 @default.
- W2097479849 hasConcept C2779548794 @default.
- W2097479849 hasConcept C2779629538 @default.
- W2097479849 hasConcept C2779978075 @default.
- W2097479849 hasConcept C2780908437 @default.
- W2097479849 hasConcept C44249647 @default.
- W2097479849 hasConcept C50440223 @default.
- W2097479849 hasConcept C71924100 @default.
- W2097479849 hasConcept C90924648 @default.
- W2097479849 hasConceptScore W2097479849C126322002 @default.
- W2097479849 hasConceptScore W2097479849C141071460 @default.
- W2097479849 hasConceptScore W2097479849C156957248 @default.
- W2097479849 hasConceptScore W2097479849C16005928 @default.
- W2097479849 hasConceptScore W2097479849C203014093 @default.
- W2097479849 hasConceptScore W2097479849C2776391196 @default.
- W2097479849 hasConceptScore W2097479849C2779548794 @default.
- W2097479849 hasConceptScore W2097479849C2779629538 @default.
- W2097479849 hasConceptScore W2097479849C2779978075 @default.
- W2097479849 hasConceptScore W2097479849C2780908437 @default.
- W2097479849 hasConceptScore W2097479849C44249647 @default.
- W2097479849 hasConceptScore W2097479849C50440223 @default.
- W2097479849 hasConceptScore W2097479849C71924100 @default.
- W2097479849 hasConceptScore W2097479849C90924648 @default.
- W2097479849 hasIssue "5" @default.
- W2097479849 hasLocation W20974798491 @default.
- W2097479849 hasLocation W20974798492 @default.
- W2097479849 hasOpenAccess W2097479849 @default.
- W2097479849 hasPrimaryLocation W20974798491 @default.
- W2097479849 hasRelatedWork W1575274098 @default.
- W2097479849 hasRelatedWork W2014963733 @default.
- W2097479849 hasRelatedWork W2095960848 @default.
- W2097479849 hasRelatedWork W2097479849 @default.
- W2097479849 hasRelatedWork W2098468742 @default.
- W2097479849 hasRelatedWork W2105807268 @default.
- W2097479849 hasRelatedWork W2111440057 @default.
- W2097479849 hasRelatedWork W2128630430 @default.
- W2097479849 hasRelatedWork W2902880117 @default.
- W2097479849 hasRelatedWork W3144285132 @default.
- W2097479849 hasVolume "52" @default.
- W2097479849 isParatext "false" @default.
- W2097479849 isRetracted "false" @default.
- W2097479849 magId "2097479849" @default.
- W2097479849 workType "article" @default.