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- W2097502227 abstract "Growth of Bacteroides fragilis and Escherichia coli was monitored during early stages of single (mono-) and mixed intra-abdominal infection in a rat fibrin clot model. When B. fragilis and E. coli were together involved in the infection, B. fragilis numbers increased about 6 h after an initial decline. This increase was not found with B. fragilis mono-infections. The numbers of E. coli increased rapidly in both mono- and mixed infections and stayed high for several days, but only mixed infection resulted in abscesses that persisted for more than 7 days. Macrophages, the main component of the peritoneal cellular defence mechanism, were outnumbered by polymorphonuclear leucocytes during the first 6 h of infection. Further characterisation of the macrophage population by means of monoclonal antibodies showed a shift from resident to exudate macrophages as the result of influx of the latter." @default.
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- W2097502227 date "1991-07-01" @default.
- W2097502227 modified "2023-10-16" @default.
- W2097502227 title "Early events after intra-abdominal infection with Bacteroides fragilis and Escherichia coli" @default.
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- W2097502227 doi "https://doi.org/10.1099/00222615-35-1-18" @default.
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