FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097515723> ?p ?o ?g. }

• W2097515723 endingPage "27" @default.
• W2097515723 startingPage "19" @default.
• W2097515723 abstract "Background. Despite effective antiretroviral therapy (ART), patients with chronic human immunodeficiency virus (HIV) infection have increased microbial translocation and systemic inflammation. Alterations in the intestinal microbiota may play a role in microbial translocation and inflammation. Methods. We profiled the fecal microbiota by pyrosequencing the gene encoding 16S ribosomal RNA (rRNA) and measured markers of microbial translocation and systemic inflammation in 21 patients who had chronic HIV infection and were receiving suppressive ART (cases) and 16 HIV-uninfected controls. Results. The fecal microbial community composition was significantly different between cases and controls. The relative abundance of Proteobacteria, Gammaproteobacteria, Enterobacteriales, Enterobacteriaceae, Erysipelotrichi, Erysipelotrichales, Erysipelotrichaceae, and Barnesiella was significantly enriched in cases, whereas that of Rikenellaceae and Alistipes was depleted. The plasma soluble CD14 level (sCD14) was significantly higher and the endotoxin core immunoglobulin M (IgM) level lower in cases, compared with controls. There were significant positive correlations between the relative abundances of Enterobacteriales and Enterobacteriaceae and the sCD14 level; the relative abundances of Gammaproteobacteria, Enterobacteriales, and Enterobacteriaceae and the interleukin 1β (IL-1β) level; the relative abundances of Enterobacteriales and Enterobacteriaceae and the interferon γ level; and the relative abundances of Erysipelotrichi and Barnesiella and the TNF-α level. There were negative correlations between endotoxin core IgM and IL-1β levels. Conclusions. Patients who have chronic HIV infection and are receiving suppressive ART display intestinal dysbiosis associated with increased microbial translocation and significant associations between specific taxa and markers of microbial translocation and systemic inflammation. This was an exploratory study, the findings of which need to be confirmed." @default.
• W2097515723 created "2016-06-24" @default.
• W2097515723 creator A5039175735 @default.
• W2097515723 creator A5041578848 @default.
• W2097515723 creator A5048320842 @default.
• W2097515723 creator A5053025574 @default.
• W2097515723 creator A5063588260 @default.
• W2097515723 creator A5083225001 @default.
• W2097515723 creator A5089516926 @default.
• W2097515723 creator A5010942291 @default.
• W2097515723 date "2014-07-23" @default.
• W2097515723 modified "2023-10-14" @default.
• W2097515723 title "Intestinal Microbiota, Microbial Translocation, and Systemic Inflammation in Chronic HIV Infection" @default.
• W2097515723 cites W151256503 @default.
• W2097515723 cites W161165769 @default.
• W2097515723 cites W1773687002 @default.
• W2097515723 cites W1966921473 @default.
• W2097515723 cites W1984486655 @default.
• W2097515723 cites W1994827009 @default.
• W2097515723 cites W1996967878 @default.
• W2097515723 cites W1997739963 @default.
• W2097515723 cites W2013017844 @default.
• W2097515723 cites W2013930482 @default.
• W2097515723 cites W2021057860 @default.
• W2097515723 cites W2033327108 @default.
• W2097515723 cites W2034635728 @default.
• W2097515723 cites W2036604576 @default.
• W2097515723 cites W2044217413 @default.
• W2097515723 cites W2048923715 @default.
• W2097515723 cites W2061845693 @default.
• W2097515723 cites W2071470175 @default.
• W2097515723 cites W2072970694 @default.
• W2097515723 cites W2080205831 @default.
• W2097515723 cites W2080416827 @default.
• W2097515723 cites W2081380467 @default.
• W2097515723 cites W2091961926 @default.
• W2097515723 cites W2098506435 @default.
• W2097515723 cites W2104318549 @default.
• W2097515723 cites W2105804574 @default.
• W2097515723 cites W2106654454 @default.
• W2097515723 cites W2110883977 @default.
• W2097515723 cites W2120495574 @default.
• W2097515723 cites W2122483069 @default.
• W2097515723 cites W2124351063 @default.
• W2097515723 cites W2128719172 @default.
• W2097515723 cites W2130603879 @default.
• W2097515723 cites W2132113202 @default.
• W2097515723 cites W2133856765 @default.
• W2097515723 cites W2146488133 @default.
• W2097515723 cites W2147024250 @default.
• W2097515723 cites W2147163488 @default.
• W2097515723 cites W2147825765 @default.
• W2097515723 cites W2149573313 @default.
• W2097515723 cites W2152885278 @default.
• W2097515723 cites W2156145269 @default.
• W2097515723 cites W2159527861 @default.
• W2097515723 cites W2167062509 @default.
• W2097515723 cites W2170850530 @default.
• W2097515723 cites W2171270480 @default.
• W2097515723 cites W2318775435 @default.
• W2097515723 cites W4237961126 @default.
• W2097515723 doi "https://doi.org/10.1093/infdis/jiu409" @default.
• W2097515723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4326316" @default.
• W2097515723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25057045" @default.
• W2097515723 hasPublicationYear "2014" @default.
• W2097515723 type Work @default.
• W2097515723 sameAs 2097515723 @default.
• W2097515723 citedByCount "340" @default.
• W2097515723 countsByYear W20975157232015 @default.
• W2097515723 countsByYear W20975157232016 @default.
• W2097515723 countsByYear W20975157232017 @default.
• W2097515723 countsByYear W20975157232018 @default.
• W2097515723 countsByYear W20975157232019 @default.
• W2097515723 countsByYear W20975157232020 @default.
• W2097515723 countsByYear W20975157232021 @default.
• W2097515723 countsByYear W20975157232022 @default.
• W2097515723 countsByYear W20975157232023 @default.
• W2097515723 crossrefType "journal-article" @default.
• W2097515723 hasAuthorship W2097515723A5010942291 @default.
• W2097515723 hasAuthorship W2097515723A5039175735 @default.
• W2097515723 hasAuthorship W2097515723A5041578848 @default.
• W2097515723 hasAuthorship W2097515723A5048320842 @default.
• W2097515723 hasAuthorship W2097515723A5053025574 @default.
• W2097515723 hasAuthorship W2097515723A5063588260 @default.
• W2097515723 hasAuthorship W2097515723A5083225001 @default.
• W2097515723 hasAuthorship W2097515723A5089516926 @default.
• W2097515723 hasBestOaLocation W20975157231 @default.
• W2097515723 hasConcept C104317684 @default.
• W2097515723 hasConcept C143121216 @default.
• W2097515723 hasConcept C203014093 @default.
• W2097515723 hasConcept C2776252253 @default.
• W2097515723 hasConcept C2776914184 @default.
• W2097515723 hasConcept C2776989901 @default.
• W2097515723 hasConcept C2777165150 @default.
• W2097515723 hasConcept C2778910516 @default.
• W2097515723 hasConcept C2780648854 @default.
• W2097515723 hasConcept C42062724 @default.
• W2097515723 hasConcept C523546767 @default.

• next