Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097542455> ?p ?o ?g. }
- W2097542455 endingPage "262" @default.
- W2097542455 startingPage "255" @default.
- W2097542455 abstract "Mortalin is a heat-non-inducible member of the heat shock protein 70 family. Mortalin binds to p53 and prevents p53 from entering the nucleus. To understand the significance of mortalin in gastric cancer, we investigated the expression of mortalin and p53.Expression of mortalin and p53 was examined by immunohistochemical staining of 182 clinical samples of gastric cancer.Mortalin-positive and aberrant p53-positive tumors were found in 75.2 and 49.5 % of cases, respectively. Mortalin-positive tumors were deeper in invasion and had more lymph node and liver metastases compared with mortalin-negative tumors (P < 0.01, P < 0.05, respectively). Mortalin-positive tumors had worse prognosis compared with mortalin-negative tumors (P = 0.035). Moreover, in tumors with normal p53 function, mortalin-positive tumors had worse prognosis compared with mortalin-negative tumors (P = 0.017).Mortalin has a great impact on gastric cancer with normal p53. Therefore, mortalin is a target molecule for treatment of gastric cancer, as well as a promising prognostic factor, especially in tumors with normal p53." @default.
- W2097542455 created "2016-06-24" @default.
- W2097542455 creator A5004420462 @default.
- W2097542455 creator A5010999012 @default.
- W2097542455 creator A5018750173 @default.
- W2097542455 creator A5019467286 @default.
- W2097542455 creator A5026111775 @default.
- W2097542455 creator A5027338063 @default.
- W2097542455 creator A5063723368 @default.
- W2097542455 creator A5065230795 @default.
- W2097542455 creator A5072378382 @default.
- W2097542455 creator A5086231834 @default.
- W2097542455 creator A5091180256 @default.
- W2097542455 date "2013-07-05" @default.
- W2097542455 modified "2023-10-12" @default.
- W2097542455 title "Mortalin is a prognostic factor of gastric cancer with normal p53 function" @default.
- W2097542455 cites W1490486327 @default.
- W2097542455 cites W1970221755 @default.
- W2097542455 cites W1970703181 @default.
- W2097542455 cites W1978968003 @default.
- W2097542455 cites W1983386156 @default.
- W2097542455 cites W1988399174 @default.
- W2097542455 cites W2007344133 @default.
- W2097542455 cites W2008715871 @default.
- W2097542455 cites W2010009570 @default.
- W2097542455 cites W2013728572 @default.
- W2097542455 cites W2023657121 @default.
- W2097542455 cites W2024996523 @default.
- W2097542455 cites W2040876807 @default.
- W2097542455 cites W2047151046 @default.
- W2097542455 cites W2048981781 @default.
- W2097542455 cites W2065102742 @default.
- W2097542455 cites W2074222004 @default.
- W2097542455 cites W2075858745 @default.
- W2097542455 cites W2095573372 @default.
- W2097542455 cites W2098147003 @default.
- W2097542455 cites W2099907467 @default.
- W2097542455 cites W2120775866 @default.
- W2097542455 cites W2122361685 @default.
- W2097542455 cites W2122796143 @default.
- W2097542455 cites W2133568563 @default.
- W2097542455 cites W2163798977 @default.
- W2097542455 cites W2330120499 @default.
- W2097542455 cites W4240334475 @default.
- W2097542455 doi "https://doi.org/10.1007/s10120-013-0279-1" @default.
- W2097542455 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23828548" @default.
- W2097542455 hasPublicationYear "2013" @default.
- W2097542455 type Work @default.
- W2097542455 sameAs 2097542455 @default.
- W2097542455 citedByCount "38" @default.
- W2097542455 countsByYear W20975424552014 @default.
- W2097542455 countsByYear W20975424552015 @default.
- W2097542455 countsByYear W20975424552016 @default.
- W2097542455 countsByYear W20975424552017 @default.
- W2097542455 countsByYear W20975424552018 @default.
- W2097542455 countsByYear W20975424552019 @default.
- W2097542455 countsByYear W20975424552021 @default.
- W2097542455 countsByYear W20975424552022 @default.
- W2097542455 crossrefType "journal-article" @default.
- W2097542455 hasAuthorship W2097542455A5004420462 @default.
- W2097542455 hasAuthorship W2097542455A5010999012 @default.
- W2097542455 hasAuthorship W2097542455A5018750173 @default.
- W2097542455 hasAuthorship W2097542455A5019467286 @default.
- W2097542455 hasAuthorship W2097542455A5026111775 @default.
- W2097542455 hasAuthorship W2097542455A5027338063 @default.
- W2097542455 hasAuthorship W2097542455A5063723368 @default.
- W2097542455 hasAuthorship W2097542455A5065230795 @default.
- W2097542455 hasAuthorship W2097542455A5072378382 @default.
- W2097542455 hasAuthorship W2097542455A5086231834 @default.
- W2097542455 hasAuthorship W2097542455A5091180256 @default.
- W2097542455 hasBestOaLocation W20975424551 @default.
- W2097542455 hasConcept C104317684 @default.
- W2097542455 hasConcept C121608353 @default.
- W2097542455 hasConcept C126322002 @default.
- W2097542455 hasConcept C142724271 @default.
- W2097542455 hasConcept C204232928 @default.
- W2097542455 hasConcept C205260736 @default.
- W2097542455 hasConcept C2780140570 @default.
- W2097542455 hasConcept C2780849966 @default.
- W2097542455 hasConcept C502942594 @default.
- W2097542455 hasConcept C55493867 @default.
- W2097542455 hasConcept C71924100 @default.
- W2097542455 hasConcept C86803240 @default.
- W2097542455 hasConcept C96232424 @default.
- W2097542455 hasConceptScore W2097542455C104317684 @default.
- W2097542455 hasConceptScore W2097542455C121608353 @default.
- W2097542455 hasConceptScore W2097542455C126322002 @default.
- W2097542455 hasConceptScore W2097542455C142724271 @default.
- W2097542455 hasConceptScore W2097542455C204232928 @default.
- W2097542455 hasConceptScore W2097542455C205260736 @default.
- W2097542455 hasConceptScore W2097542455C2780140570 @default.
- W2097542455 hasConceptScore W2097542455C2780849966 @default.
- W2097542455 hasConceptScore W2097542455C502942594 @default.
- W2097542455 hasConceptScore W2097542455C55493867 @default.
- W2097542455 hasConceptScore W2097542455C71924100 @default.
- W2097542455 hasConceptScore W2097542455C86803240 @default.
- W2097542455 hasConceptScore W2097542455C96232424 @default.
- W2097542455 hasIssue "2" @default.