Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097554173> ?p ?o ?g. }
- W2097554173 abstract "Matrix metalloproteinases (MMPs) are a group of endopeptidases which comprised of various types. These proteolytic enzymes are zinc-dependent and play role in degradation of extracellular matrix (ECM). Various types of cells such as macrophages, fibroblasts, neutrophils, synovial cells and some epithelial cells secrete MMPs. According to previous studies on bronchiolitis and respiratory tract lesions in these patients and unknown pathophysiology mechanism up to date, this cross-sectional study was performed.The aim of this study was to compare the serum MMP level in patients with chemical injuries and normal people and also determine the role of these parameters in pulmonary disorders .In this cross-sectional study, 25 Iranian patients exposed to the sulfur mustard and 25 unexposed participants as the control group were enrolled. Serum samples were collected from two groups and stored at -70˚C until the measurement of MMPs and TIMPs. ELISA kit was used for measurement of MMP and TIMP based on the kit's instruction. For validations in measurement, all samples were analyzed duplicate and in some cases triplicate.The mean level of MMP-9 in serum of chemically-injured group was 1592.42 and this amount in normal group was 679.72 .So there was a significant difference between two groups (P = 0.001) and the mean level of MMP-8 in serum of patients group was 49.10 and in normal group was 35.53. Then there was no significant difference between two groups (P = 0.197). The mean levels of MMP-1 and MMP-2 was not significantly different (P value > 0.05) in the patient and normal groups. And also the mean levels of TIMP-1 and TIMP-2 was not significantly different (P > 0.05) in the patients and normal groups.In summary, serum MMPs in chemically-injured has shown no significant difference with normal people except for the MMP-9." @default.
- W2097554173 created "2016-06-24" @default.
- W2097554173 creator A5000185970 @default.
- W2097554173 creator A5006574006 @default.
- W2097554173 creator A5026689362 @default.
- W2097554173 creator A5031069693 @default.
- W2097554173 creator A5038203898 @default.
- W2097554173 creator A5039278654 @default.
- W2097554173 date "2014-03-05" @default.
- W2097554173 modified "2023-10-18" @default.
- W2097554173 title "Serum Matrix Metalloproteinase Levels in Patients Exposed to Sulfur Mustard" @default.
- W2097554173 cites W1516887928 @default.
- W2097554173 cites W1581868641 @default.
- W2097554173 cites W1806896498 @default.
- W2097554173 cites W1964496770 @default.
- W2097554173 cites W1972738314 @default.
- W2097554173 cites W1981879083 @default.
- W2097554173 cites W1990550896 @default.
- W2097554173 cites W1990584310 @default.
- W2097554173 cites W2008351471 @default.
- W2097554173 cites W2025812706 @default.
- W2097554173 cites W2040557727 @default.
- W2097554173 cites W2044164946 @default.
- W2097554173 cites W2047902104 @default.
- W2097554173 cites W2051046198 @default.
- W2097554173 cites W2057366656 @default.
- W2097554173 cites W2057693137 @default.
- W2097554173 cites W2058857878 @default.
- W2097554173 cites W2068827751 @default.
- W2097554173 cites W2078823089 @default.
- W2097554173 cites W2091076126 @default.
- W2097554173 cites W2099170891 @default.
- W2097554173 cites W2102869731 @default.
- W2097554173 cites W2106965417 @default.
- W2097554173 cites W2128049766 @default.
- W2097554173 cites W2153420545 @default.
- W2097554173 cites W1972527162 @default.
- W2097554173 doi "https://doi.org/10.5812/ircmj.15129" @default.
- W2097554173 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4005442" @default.
- W2097554173 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24829780" @default.
- W2097554173 hasPublicationYear "2014" @default.
- W2097554173 type Work @default.
- W2097554173 sameAs 2097554173 @default.
- W2097554173 citedByCount "20" @default.
- W2097554173 countsByYear W20975541732015 @default.
- W2097554173 countsByYear W20975541732016 @default.
- W2097554173 countsByYear W20975541732017 @default.
- W2097554173 countsByYear W20975541732018 @default.
- W2097554173 countsByYear W20975541732019 @default.
- W2097554173 countsByYear W20975541732020 @default.
- W2097554173 countsByYear W20975541732021 @default.
- W2097554173 countsByYear W20975541732022 @default.
- W2097554173 countsByYear W20975541732023 @default.
- W2097554173 crossrefType "journal-article" @default.
- W2097554173 hasAuthorship W2097554173A5000185970 @default.
- W2097554173 hasAuthorship W2097554173A5006574006 @default.
- W2097554173 hasAuthorship W2097554173A5026689362 @default.
- W2097554173 hasAuthorship W2097554173A5031069693 @default.
- W2097554173 hasAuthorship W2097554173A5038203898 @default.
- W2097554173 hasAuthorship W2097554173A5039278654 @default.
- W2097554173 hasBestOaLocation W20975541732 @default.
- W2097554173 hasConcept C10162356 @default.
- W2097554173 hasConcept C109523444 @default.
- W2097554173 hasConcept C126322002 @default.
- W2097554173 hasConcept C142724271 @default.
- W2097554173 hasConcept C189165786 @default.
- W2097554173 hasConcept C203014093 @default.
- W2097554173 hasConcept C2779644171 @default.
- W2097554173 hasConcept C2779965577 @default.
- W2097554173 hasConcept C2780644109 @default.
- W2097554173 hasConcept C29730261 @default.
- W2097554173 hasConcept C534529494 @default.
- W2097554173 hasConcept C55493867 @default.
- W2097554173 hasConcept C71924100 @default.
- W2097554173 hasConcept C86803240 @default.
- W2097554173 hasConcept C90924648 @default.
- W2097554173 hasConceptScore W2097554173C10162356 @default.
- W2097554173 hasConceptScore W2097554173C109523444 @default.
- W2097554173 hasConceptScore W2097554173C126322002 @default.
- W2097554173 hasConceptScore W2097554173C142724271 @default.
- W2097554173 hasConceptScore W2097554173C189165786 @default.
- W2097554173 hasConceptScore W2097554173C203014093 @default.
- W2097554173 hasConceptScore W2097554173C2779644171 @default.
- W2097554173 hasConceptScore W2097554173C2779965577 @default.
- W2097554173 hasConceptScore W2097554173C2780644109 @default.
- W2097554173 hasConceptScore W2097554173C29730261 @default.
- W2097554173 hasConceptScore W2097554173C534529494 @default.
- W2097554173 hasConceptScore W2097554173C55493867 @default.
- W2097554173 hasConceptScore W2097554173C71924100 @default.
- W2097554173 hasConceptScore W2097554173C86803240 @default.
- W2097554173 hasConceptScore W2097554173C90924648 @default.
- W2097554173 hasIssue "3" @default.
- W2097554173 hasLocation W20975541731 @default.
- W2097554173 hasLocation W20975541732 @default.
- W2097554173 hasLocation W20975541733 @default.
- W2097554173 hasLocation W20975541734 @default.
- W2097554173 hasOpenAccess W2097554173 @default.
- W2097554173 hasPrimaryLocation W20975541731 @default.
- W2097554173 hasRelatedWork W1547122119 @default.
- W2097554173 hasRelatedWork W1991507260 @default.