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• W2097561036 abstract "This paper considers the problem of optimal false discovery rate control when the test statistics are dependent. An optimal joint oracle procedure, which minimizes the false non-discovery rate subject to a constraint on the false discovery rate is developed. A data-driven marginal plug-in procedure is then proposed to approximate the optimal joint procedure for multivariate normal data. It is shown that the marginal procedure is asymptotically optimal for multivariate normal data with a short-range dependent covariance structure. Numerical results show that the marginal procedure controls false discovery rate and leads to a smaller false non-discovery rate than several commonly used p-value based false discovery rate controlling methods. The procedure is illustrated by an application to a genome-wide association study of neuroblastoma and it identifies a few more genetic variants that are potentially associated with neuroblastoma than several p-value-based false discovery rate controlling procedures." @default.
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• W2097561036 date "2011-01-01" @default.
• W2097561036 modified "2023-09-30" @default.
• W2097561036 title "Optimal false discovery rate control for dependent data" @default.
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• W2097561036 doi "https://doi.org/10.4310/sii.2011.v4.n4.a1" @default.
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