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• W2097564650 endingPage "2014" @default.
• W2097564650 startingPage "2003" @default.
• W2097564650 abstract "Absorption, distribution, metabolism and excretion (ADME) data are pivotal for small-molecule drug development, with well-developed in vitro and in vivo correlation tools and guidances from regulatory agencies. In the past two decades, monoclonal antibody (mAb) biotherapeutics have been successfully approved, including derived novel conjugates of active molecules (toxins or bioactive peptides) for specific target delivery or half-life extension. However, ADME information of mAb therapeutics lags behind that of small molecules due to the complex nature of the molecules and lack of appropriate tools to study drug exposure, biotransformation, and target engagement in the vascular and tissue spaces. In this perspective, the current knowledge gaps on ADME of mAb-related therapeutics are reviewed with potential solutions from emerging analytical technologies." @default.
• W2097564650 created "2016-06-24" @default.
• W2097564650 creator A5065655179 @default.
• W2097564650 date "2013-08-01" @default.
• W2097564650 modified "2023-09-27" @default.
• W2097564650 title "ADME of monoclonal antibody biotherapeutics: knowledge gaps and emerging tools" @default.
• W2097564650 cites W110477109 @default.
• W2097564650 cites W1203637170 @default.
• W2097564650 cites W1544644780 @default.
• W2097564650 cites W1926541123 @default.
• W2097564650 cites W1967874097 @default.
• W2097564650 cites W1969671154 @default.
• W2097564650 cites W1970593964 @default.
• W2097564650 cites W1971535269 @default.
• W2097564650 cites W1978261191 @default.
• W2097564650 cites W1978807468 @default.
• W2097564650 cites W1982462083 @default.
• W2097564650 cites W1987706198 @default.
• W2097564650 cites W1989958259 @default.
• W2097564650 cites W1990183246 @default.
• W2097564650 cites W1995923662 @default.
• W2097564650 cites W1996045402 @default.
• W2097564650 cites W1996366496 @default.
• W2097564650 cites W1997454484 @default.
• W2097564650 cites W2001228013 @default.
• W2097564650 cites W2003495422 @default.
• W2097564650 cites W2005575131 @default.
• W2097564650 cites W2008341781 @default.
• W2097564650 cites W2011077241 @default.
• W2097564650 cites W2013191780 @default.
• W2097564650 cites W2013321603 @default.
• W2097564650 cites W2015244046 @default.
• W2097564650 cites W2023965289 @default.
• W2097564650 cites W2024626836 @default.
• W2097564650 cites W2029197822 @default.
• W2097564650 cites W2029435208 @default.
• W2097564650 cites W2031160951 @default.
• W2097564650 cites W2031911756 @default.
• W2097564650 cites W2032353819 @default.
• W2097564650 cites W2032754679 @default.
• W2097564650 cites W2033699650 @default.
• W2097564650 cites W2035610264 @default.
• W2097564650 cites W2037347562 @default.
• W2097564650 cites W2039037168 @default.
• W2097564650 cites W2039144093 @default.
• W2097564650 cites W2044643025 @default.
• W2097564650 cites W2048954270 @default.
• W2097564650 cites W2051363346 @default.
• W2097564650 cites W2052789788 @default.
• W2097564650 cites W2056439160 @default.
• W2097564650 cites W2057362015 @default.
• W2097564650 cites W2058298068 @default.
• W2097564650 cites W2058648267 @default.
• W2097564650 cites W2059050919 @default.
• W2097564650 cites W2062826169 @default.
• W2097564650 cites W2065812641 @default.
• W2097564650 cites W2066751846 @default.
• W2097564650 cites W2066865216 @default.
• W2097564650 cites W2067874068 @default.
• W2097564650 cites W2071843728 @default.
• W2097564650 cites W2071955492 @default.
• W2097564650 cites W2075678951 @default.
• W2097564650 cites W2079412905 @default.
• W2097564650 cites W2080787903 @default.
• W2097564650 cites W2081221548 @default.
• W2097564650 cites W2086479289 @default.
• W2097564650 cites W2086482125 @default.
• W2097564650 cites W2097742807 @default.
• W2097564650 cites W2104446771 @default.
• W2097564650 cites W2104792106 @default.
• W2097564650 cites W2107755102 @default.
• W2097564650 cites W2110539456 @default.
• W2097564650 cites W2113969634 @default.
• W2097564650 cites W2117706704 @default.
• W2097564650 cites W2122099202 @default.
• W2097564650 cites W2124040259 @default.
• W2097564650 cites W2124847934 @default.
• W2097564650 cites W2130611069 @default.
• W2097564650 cites W2133161896 @default.
• W2097564650 cites W2134252280 @default.
• W2097564650 cites W2138572955 @default.
• W2097564650 cites W2145489114 @default.
• W2097564650 cites W2145533061 @default.
• W2097564650 cites W2151568835 @default.
• W2097564650 cites W2152083346 @default.
• W2097564650 cites W2153166088 @default.
• W2097564650 cites W2155951093 @default.
• W2097564650 cites W2156023807 @default.
• W2097564650 cites W2158858604 @default.
• W2097564650 cites W2158883604 @default.
• W2097564650 cites W2159562550 @default.
• W2097564650 cites W2162360553 @default.
• W2097564650 cites W2163899224 @default.
• W2097564650 cites W2171136826 @default.
• W2097564650 cites W2317211257 @default.
• W2097564650 cites W35891342 @default.
• W2097564650 cites W39791225 @default.
• W2097564650 doi "https://doi.org/10.4155/bio.13.144" @default.

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