Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097598853> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2097598853 abstract "Segmental liver hyperintensity can be observed in malignant biliary obstruction on diffusion weighted MRI (DW-MRI). We describe MRI findings associated with this sign and evaluate whether DW-MRI segmental hyperintensity has any relationship with serum alanine aminotransferase (ALT) levels.The DW-MRI T(1) weighted, T(2) weighted and gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced T(1) weighted images obtained in 21 patients with hepatic malignancy, who demonstrated biliary obstruction and segmental hyperintensity on DW-MRI (b=0-750 s mm(-2)), were retrospectively reviewed by 2 readers blinded to clinical results. DW-MRI hyperintense liver segments were recorded as hypointense, isointense or hyperintense relative to normal liver on T(1)/T(2) weighted imaging. It was also noted whether contrast enhancement was similar to that observed in normal liver or diminished in the hepatocellular phase. The mean apparent diffusion coefficient (ADC) value (×10(-3) s mm(-2)) of DW-MRI hyperintense segments, normal liver and tumour were compared using Student's t-test. The frequency of MRI findings was corroborated with serum ALT levels, which reflect hepatocyte injury.DW-MRI hyperintense segments frequently showed T(1) hyperintensity (10/21), T(2) hyperintensity (19/21) and/or diminished contrast enhancement (15/21). Tumours showed significantly lower mean ADC values than liver (1.23 ± 0.08 vs 1.43 ± 0.05; p=0.013). Segments showing concomitant T(1) hyperintensity had lower mean ADC values than liver (1.30 ± 0.05 vs 1.43 ± 0.05; p=0.023). The patients (8/10) with concomitant T(1) and DW-MRI segmental hyperintensity showed elevated ALT levels (p=0.030, Fisher's exact test).Concomitantly high T(1) weighted and DW-MRI signal in liver segments was associated with lower ADC values and abnormal liver function tests, which could reflect underlying cellular swelling and damage." @default.
- W2097598853 created "2016-06-24" @default.
- W2097598853 creator A5022609560 @default.
- W2097598853 creator A5038368582 @default.
- W2097598853 creator A5040106089 @default.
- W2097598853 creator A5055542280 @default.
- W2097598853 creator A5057376571 @default.
- W2097598853 creator A5084395158 @default.
- W2097598853 date "2012-01-01" @default.
- W2097598853 modified "2023-10-02" @default.
- W2097598853 title "Segmental liver hyperintensity in malignant biliary obstruction on diffusion weighted MRI: associated MRI findings and relationship with serum alanine aminotransferase levels" @default.
- W2097598853 cites W1974055353 @default.
- W2097598853 cites W1979530620 @default.
- W2097598853 cites W1985034545 @default.
- W2097598853 cites W1993950135 @default.
- W2097598853 cites W2009606774 @default.
- W2097598853 cites W2046592338 @default.
- W2097598853 cites W2048125383 @default.
- W2097598853 cites W2056108089 @default.
- W2097598853 cites W2065945867 @default.
- W2097598853 cites W2077158059 @default.
- W2097598853 cites W2081431739 @default.
- W2097598853 cites W2115467118 @default.
- W2097598853 cites W2143724876 @default.
- W2097598853 cites W2321700180 @default.
- W2097598853 cites W4231088941 @default.
- W2097598853 doi "https://doi.org/10.1259/bjr/24852804" @default.
- W2097598853 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3473925" @default.
- W2097598853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21224301" @default.
- W2097598853 hasPublicationYear "2012" @default.
- W2097598853 type Work @default.
- W2097598853 sameAs 2097598853 @default.
- W2097598853 citedByCount "10" @default.
- W2097598853 countsByYear W20975988532012 @default.
- W2097598853 countsByYear W20975988532013 @default.
- W2097598853 countsByYear W20975988532014 @default.
- W2097598853 countsByYear W20975988532015 @default.
- W2097598853 countsByYear W20975988532016 @default.
- W2097598853 countsByYear W20975988532017 @default.
- W2097598853 countsByYear W20975988532018 @default.
- W2097598853 countsByYear W20975988532019 @default.
- W2097598853 crossrefType "journal-article" @default.
- W2097598853 hasAuthorship W2097598853A5022609560 @default.
- W2097598853 hasAuthorship W2097598853A5038368582 @default.
- W2097598853 hasAuthorship W2097598853A5040106089 @default.
- W2097598853 hasAuthorship W2097598853A5055542280 @default.
- W2097598853 hasAuthorship W2097598853A5057376571 @default.
- W2097598853 hasAuthorship W2097598853A5084395158 @default.
- W2097598853 hasBestOaLocation W20975988532 @default.
- W2097598853 hasConcept C126838900 @default.
- W2097598853 hasConcept C142724271 @default.
- W2097598853 hasConcept C143409427 @default.
- W2097598853 hasConcept C146638467 @default.
- W2097598853 hasConcept C149550507 @default.
- W2097598853 hasConcept C2779399171 @default.
- W2097598853 hasConcept C2989005 @default.
- W2097598853 hasConcept C70816921 @default.
- W2097598853 hasConcept C71924100 @default.
- W2097598853 hasConceptScore W2097598853C126838900 @default.
- W2097598853 hasConceptScore W2097598853C142724271 @default.
- W2097598853 hasConceptScore W2097598853C143409427 @default.
- W2097598853 hasConceptScore W2097598853C146638467 @default.
- W2097598853 hasConceptScore W2097598853C149550507 @default.
- W2097598853 hasConceptScore W2097598853C2779399171 @default.
- W2097598853 hasConceptScore W2097598853C2989005 @default.
- W2097598853 hasConceptScore W2097598853C70816921 @default.
- W2097598853 hasConceptScore W2097598853C71924100 @default.
- W2097598853 hasLocation W20975988531 @default.
- W2097598853 hasLocation W20975988532 @default.
- W2097598853 hasLocation W20975988533 @default.
- W2097598853 hasLocation W20975988534 @default.
- W2097598853 hasOpenAccess W2097598853 @default.
- W2097598853 hasPrimaryLocation W20975988531 @default.
- W2097598853 hasRelatedWork W1503078909 @default.
- W2097598853 hasRelatedWork W1977857100 @default.
- W2097598853 hasRelatedWork W2053346220 @default.
- W2097598853 hasRelatedWork W2067447833 @default.
- W2097598853 hasRelatedWork W2068078637 @default.
- W2097598853 hasRelatedWork W2072137120 @default.
- W2097598853 hasRelatedWork W2112093935 @default.
- W2097598853 hasRelatedWork W2147714948 @default.
- W2097598853 hasRelatedWork W2361547640 @default.
- W2097598853 hasRelatedWork W2365393612 @default.
- W2097598853 hasRelatedWork W2369552425 @default.
- W2097598853 hasRelatedWork W2381327165 @default.
- W2097598853 hasRelatedWork W2382418576 @default.
- W2097598853 hasRelatedWork W2392915044 @default.
- W2097598853 hasRelatedWork W2393848254 @default.
- W2097598853 hasRelatedWork W2426891091 @default.
- W2097598853 hasRelatedWork W2553096064 @default.
- W2097598853 hasRelatedWork W2793730493 @default.
- W2097598853 hasRelatedWork W3031124380 @default.
- W2097598853 hasRelatedWork W2006492531 @default.
- W2097598853 isParatext "false" @default.
- W2097598853 isRetracted "false" @default.
- W2097598853 magId "2097598853" @default.
- W2097598853 workType "article" @default.