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• W2097614902 abstract "Abstract Background Pemphigus vulgaris (PV) is a rare autoimmune blistering disease of the skin and mucous membranes. It varies in its clinical profile and epidemiologic characteristics in different parts of the world. Objective To determine the clinical features of PV in Iran in a prospective manner. Methods The study included 140 patients with newly registered PV attending our dermatology clinic between January 2003 and June 2004. Results The mean age at the onset of the disease was 41.5 ± 15.7 years, with a female to male ratio of 1.59 : 1. At presentation to our clinic, both skin and mucosal involvement was observed in 95 patients (67.9%). Cutaneous lesions without the involvement of the mucous membranes were seen in nine patients (6.4%), and exclusive mucosal involvement was present in 36 patients (25.7%). The most common initial localization of the disease was the oral cavity, which was involved in 93 patients (77.5%). The most frequent cutaneous and mucosal sites involved were the thorax and oral cavity, respectively. Conclusion Although minor differences were noted, the results of this study are in relatively good agreement with the literature with regard to the age, gender, and initial presentation of PV in Iran. Some skin sites, such as the scalp, thorax, and axilla, may be more commonly affected in men. Patients with initial mucosal lesions were significantly younger than those with initial cutaneous involvement. Mucosal lesions other than the oral mucosa may be more common than previously thought." @default.
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• W2097614902 date "2007-11-01" @default.
• W2097614902 modified "2023-10-16" @default.
• W2097614902 title "Pemphigus vulgaris in Iran: a clinical study of 140 cases" @default.
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• W2097614902 doi "https://doi.org/10.1111/j.1365-4632.2007.03334.x" @default.
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