FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097627069> ?p ?o ?g. }

• W2097627069 endingPage "222" @default.
• W2097627069 startingPage "217" @default.
• W2097627069 abstract "Numerous reports have documented a high occurrence of sleep difficulties in drug-dependent populations, prompting researchers to characterize sleep profiles and physiology in drug abusing populations. This mini-review examines studies indicating that drug-dependent populations exhibit alterations in sleep homeostatic and restoration processes in response to sleep deprivation. Sleep deprivation is a principal sleep research tool that results in marked physiological challenge, which provides a means to examine sleep homeostatic processes in response to extended wakefulness. A report from our laboratory demonstrated that following recovery sleep from sleep deprivation, brain high-energy phosphates particularly beta–nucleoside triphosphate (beta-NTP) are markedly increased as measured with phosphorus magnetic resonance spectroscopy (MRS). A more recent study examined the effects of sleep deprivation in opiate-dependent methadone-maintained (MM) subjects. The study demonstrated increases in brain beta-NTP following recovery sleep. Interestingly, these increases were of a markedly greater magnitude in MM subjects compared to control subjects. A similar study examined sleep deprivation in cocaine-dependent subjects demonstrating that cocaine-dependent subjects exhibit greater increases in brain beta-NTP following recovery sleep when compared to control subjects. The studies suggest that sleep deprivation in both MM subjects and cocaine-dependent subjects is characterized by greater changes in brain ATP levels than control subjects. Greater enhancements in brain ATP following recovery sleep may reflect a greater disruption to or impact of sleep deprivation in drug dependent subjects, whereby sleep restoration processes may be unable to properly regulate brain ATP and maintain brain high-energy equilibrium. These studies support the notion of a greater susceptibility to sleep loss in drug dependent populations. Additional sleep studies in drug abusing populations are needed, particularly those that examine potential differential effects of sleep deprivation." @default.
• W2097627069 created "2016-06-24" @default.
• W2097627069 creator A5005433179 @default.
• W2097627069 creator A5057436523 @default.
• W2097627069 creator A5057767291 @default.
• W2097627069 creator A5081926662 @default.
• W2097627069 date "2007-01-01" @default.
• W2097627069 modified "2023-10-16" @default.
• W2097627069 title "Brain Phosphorus Magnetic Resonance Spectroscopy Imaging of Sleep Homeostasis and Restoration in Drug Dependence" @default.
• W2097627069 cites W149451143 @default.
• W2097627069 cites W1509748757 @default.
• W2097627069 cites W1512105707 @default.
• W2097627069 cites W1555810878 @default.
• W2097627069 cites W1765940783 @default.
• W2097627069 cites W193043798 @default.
• W2097627069 cites W1949006326 @default.
• W2097627069 cites W1963744902 @default.
• W2097627069 cites W1971479643 @default.
• W2097627069 cites W1974671405 @default.
• W2097627069 cites W1979921133 @default.
• W2097627069 cites W1984197337 @default.
• W2097627069 cites W1986468995 @default.
• W2097627069 cites W1989878117 @default.
• W2097627069 cites W1989988880 @default.
• W2097627069 cites W2001735176 @default.
• W2097627069 cites W2002382519 @default.
• W2097627069 cites W2005613803 @default.
• W2097627069 cites W2009338740 @default.
• W2097627069 cites W2009747355 @default.
• W2097627069 cites W2015906010 @default.
• W2097627069 cites W2018590161 @default.
• W2097627069 cites W2023032706 @default.
• W2097627069 cites W2035317919 @default.
• W2097627069 cites W2042716589 @default.
• W2097627069 cites W2050028535 @default.
• W2097627069 cites W2058414380 @default.
• W2097627069 cites W2066856314 @default.
• W2097627069 cites W2069633448 @default.
• W2097627069 cites W2069943414 @default.
• W2097627069 cites W2074150435 @default.
• W2097627069 cites W2074287439 @default.
• W2097627069 cites W2075349778 @default.
• W2097627069 cites W2075690792 @default.
• W2097627069 cites W2075961639 @default.
• W2097627069 cites W2079236941 @default.
• W2097627069 cites W2084071932 @default.
• W2097627069 cites W2089853720 @default.
• W2097627069 cites W2093996714 @default.
• W2097627069 cites W2094761105 @default.
• W2097627069 cites W2100138491 @default.
• W2097627069 cites W2111267491 @default.
• W2097627069 cites W2117761894 @default.
• W2097627069 cites W2118252740 @default.
• W2097627069 cites W2122215269 @default.
• W2097627069 cites W2126683149 @default.
• W2097627069 cites W2134977136 @default.
• W2097627069 cites W2136824414 @default.
• W2097627069 cites W2140411869 @default.
• W2097627069 cites W2150850854 @default.
• W2097627069 cites W2150977705 @default.
• W2097627069 cites W2153164069 @default.
• W2097627069 cites W2153762265 @default.
• W2097627069 cites W2157614293 @default.
• W2097627069 cites W2159144138 @default.
• W2097627069 cites W2160042579 @default.
• W2097627069 cites W2169668550 @default.
• W2097627069 cites W2185332678 @default.
• W2097627069 cites W2395774296 @default.
• W2097627069 cites W2403410293 @default.
• W2097627069 cites W2412361436 @default.
• W2097627069 cites W2415883048 @default.
• W2097627069 cites W2462547594 @default.
• W2097627069 cites W2471853018 @default.
• W2097627069 doi "https://doi.org/10.1100/tsw.2007.233" @default.
• W2097627069 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5901292" @default.
• W2097627069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17982596" @default.
• W2097627069 hasPublicationYear "2007" @default.
• W2097627069 type Work @default.
• W2097627069 sameAs 2097627069 @default.
• W2097627069 citedByCount "5" @default.
• W2097627069 countsByYear W20976270692014 @default.
• W2097627069 countsByYear W20976270692015 @default.
• W2097627069 crossrefType "journal-article" @default.
• W2097627069 hasAuthorship W2097627069A5005433179 @default.
• W2097627069 hasAuthorship W2097627069A5057436523 @default.
• W2097627069 hasAuthorship W2097627069A5057767291 @default.
• W2097627069 hasAuthorship W2097627069A5081926662 @default.
• W2097627069 hasBestOaLocation W20976270691 @default.
• W2097627069 hasConcept C111919701 @default.
• W2097627069 hasConcept C121446783 @default.
• W2097627069 hasConcept C126322002 @default.
• W2097627069 hasConcept C134018914 @default.
• W2097627069 hasConcept C15744967 @default.
• W2097627069 hasConcept C169760540 @default.
• W2097627069 hasConcept C2775841894 @default.
• W2097627069 hasConcept C2778321163 @default.
• W2097627069 hasConcept C2778329153 @default.
• W2097627069 hasConcept C2779320081 @default.

• next