Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097655320> ?p ?o ?g. }
- W2097655320 endingPage "2413" @default.
- W2097655320 startingPage "2407" @default.
- W2097655320 abstract "Recent epidemiologic studies suggest that uric acid predicts the development of new-onset kidney disease, but it is unclear whether uric acid is an independent risk factor. In this study, data from 21,475 healthy volunteers who were followed prospectively for a median of 7 yr were analyzed to examine the association between uric acid level and incident kidney disease (estimated GFR [eGFR] <60 ml/min per 1.73 m(2)). After adjustment for baseline eGFR, a slightly elevated uric acid level (7.0 to 8.9 mg/dl) was associated with a nearly doubled risk for incident kidney disease (odds ratio 1.74; 95% confidence interval 1.45 to 2.09), and an elevated uric acid (> or =9.0 mg/dl) was associated with a tripled risk (odds ratio 3.12; 95% confidence interval 2.29 to 4.25). These increases in risk remained significant even after adjustment for baseline eGFR, gender, age, antihypertensive drugs, and components of the metabolic syndrome (waist circumference, HDL cholesterol, blood glucose, triglycerides, and BP). In a fully adjusted spline model, the risk for incident kidney disease increased roughly linearly with uric acid level to a level of approximately 6 to 7 mg/dl in women and 7 to 8 mg/dl in men; above these levels, the associated risk increased rapidly. In conclusion, elevated levels of uric acid independently increase the risk for new-onset kidney disease." @default.
- W2097655320 created "2016-06-24" @default.
- W2097655320 creator A5057262840 @default.
- W2097655320 creator A5061041169 @default.
- W2097655320 creator A5069238987 @default.
- W2097655320 creator A5072993931 @default.
- W2097655320 creator A5083141638 @default.
- W2097655320 creator A5085805645 @default.
- W2097655320 date "2008-12-01" @default.
- W2097655320 modified "2023-10-13" @default.
- W2097655320 title "Elevated Uric Acid Increases the Risk for Kidney Disease" @default.
- W2097655320 cites W1965708830 @default.
- W2097655320 cites W1975649173 @default.
- W2097655320 cites W1981970630 @default.
- W2097655320 cites W1983441259 @default.
- W2097655320 cites W1993400379 @default.
- W2097655320 cites W1995077681 @default.
- W2097655320 cites W2007789292 @default.
- W2097655320 cites W2009053737 @default.
- W2097655320 cites W2019266035 @default.
- W2097655320 cites W2029615800 @default.
- W2097655320 cites W2045516356 @default.
- W2097655320 cites W2048113580 @default.
- W2097655320 cites W2048553694 @default.
- W2097655320 cites W2053336246 @default.
- W2097655320 cites W2055864845 @default.
- W2097655320 cites W2082236694 @default.
- W2097655320 cites W2087037896 @default.
- W2097655320 cites W2088223659 @default.
- W2097655320 cites W2089357919 @default.
- W2097655320 cites W2089804373 @default.
- W2097655320 cites W2090874502 @default.
- W2097655320 cites W2093892811 @default.
- W2097655320 cites W2096521438 @default.
- W2097655320 cites W2100707274 @default.
- W2097655320 cites W2103714496 @default.
- W2097655320 cites W2104681259 @default.
- W2097655320 cites W2105044392 @default.
- W2097655320 cites W2106362601 @default.
- W2097655320 cites W2106403351 @default.
- W2097655320 cites W2107195787 @default.
- W2097655320 cites W2117842210 @default.
- W2097655320 cites W2129958019 @default.
- W2097655320 cites W2131569787 @default.
- W2097655320 cites W2142045810 @default.
- W2097655320 cites W2145537373 @default.
- W2097655320 cites W2147946942 @default.
- W2097655320 cites W2156121263 @default.
- W2097655320 cites W2169831409 @default.
- W2097655320 cites W2185461071 @default.
- W2097655320 cites W2326669457 @default.
- W2097655320 doi "https://doi.org/10.1681/asn.2008010080" @default.
- W2097655320 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2588108" @default.
- W2097655320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18799720" @default.
- W2097655320 hasPublicationYear "2008" @default.
- W2097655320 type Work @default.
- W2097655320 sameAs 2097655320 @default.
- W2097655320 citedByCount "525" @default.
- W2097655320 countsByYear W20976553202012 @default.
- W2097655320 countsByYear W20976553202013 @default.
- W2097655320 countsByYear W20976553202014 @default.
- W2097655320 countsByYear W20976553202015 @default.
- W2097655320 countsByYear W20976553202016 @default.
- W2097655320 countsByYear W20976553202017 @default.
- W2097655320 countsByYear W20976553202018 @default.
- W2097655320 countsByYear W20976553202019 @default.
- W2097655320 countsByYear W20976553202020 @default.
- W2097655320 countsByYear W20976553202021 @default.
- W2097655320 countsByYear W20976553202022 @default.
- W2097655320 countsByYear W20976553202023 @default.
- W2097655320 crossrefType "journal-article" @default.
- W2097655320 hasAuthorship W2097655320A5057262840 @default.
- W2097655320 hasAuthorship W2097655320A5061041169 @default.
- W2097655320 hasAuthorship W2097655320A5069238987 @default.
- W2097655320 hasAuthorship W2097655320A5072993931 @default.
- W2097655320 hasAuthorship W2097655320A5083141638 @default.
- W2097655320 hasAuthorship W2097655320A5085805645 @default.
- W2097655320 hasBestOaLocation W20976553201 @default.
- W2097655320 hasConcept C126322002 @default.
- W2097655320 hasConcept C134018914 @default.
- W2097655320 hasConcept C156957248 @default.
- W2097655320 hasConcept C2776193436 @default.
- W2097655320 hasConcept C2778653478 @default.
- W2097655320 hasConcept C2779881121 @default.
- W2097655320 hasConcept C2780221984 @default.
- W2097655320 hasConcept C44249647 @default.
- W2097655320 hasConcept C50440223 @default.
- W2097655320 hasConcept C71924100 @default.
- W2097655320 hasConcept C90924648 @default.
- W2097655320 hasConceptScore W2097655320C126322002 @default.
- W2097655320 hasConceptScore W2097655320C134018914 @default.
- W2097655320 hasConceptScore W2097655320C156957248 @default.
- W2097655320 hasConceptScore W2097655320C2776193436 @default.
- W2097655320 hasConceptScore W2097655320C2778653478 @default.
- W2097655320 hasConceptScore W2097655320C2779881121 @default.
- W2097655320 hasConceptScore W2097655320C2780221984 @default.
- W2097655320 hasConceptScore W2097655320C44249647 @default.
- W2097655320 hasConceptScore W2097655320C50440223 @default.