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• W2097687932 abstract "Hypofractionated radiotherapy (HFRT) is an effective and increasingly-used treatment for early stage non-small cell lung cancer (NSCLC). Stereotactic ablative radiotherapy (SABR) is a form of HFRT and delivers biologically effective doses (BEDs) in excess of 100 Gy10 in 3-8 fractions. Excellent long-term outcomes have been reported; however, response assessment following SABR is complicated as radiation induced lung injury can appear similar to a recurring tumor on CT. Current approaches to scoring treatment responses include Response Evaluation Criteria in Solid Tumors (RECIST) and positron emission tomography (PET), both of which appear to have a limited role in detecting recurrences following SABR. Novel approaches to assess response are required, but new techniques should be easily standardized across centers, cost effective, with sensitivity and specificity that improves on current CT and PET approaches. This review examines potential novel approaches, focusing on the emerging field of quantitative image feature analysis, to distinguish recurrence from fibrosis after SABR." @default.
• W2097687932 created "2016-06-24" @default.
• W2097687932 creator A5001581360 @default.
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• W2097687932 date "2014-04-01" @default.
• W2097687932 modified "2023-09-22" @default.
• W2097687932 title "New techniques for assessing response after hypofractionated radiotherapy for lung cancer." @default.
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• W2097687932 doi "https://doi.org/10.3978/j.issn.2072-1439.2013.11.09" @default.
• W2097687932 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3968559" @default.
• W2097687932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24688782" @default.
• W2097687932 hasPublicationYear "2014" @default.
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