Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097716692> ?p ?o ?g. }
- W2097716692 endingPage "1802" @default.
- W2097716692 startingPage "1793" @default.
- W2097716692 abstract "Brain motivational circuitry in human adolescence is poorly characterized. One theory holds that risky behavior in adolescence results in part from a relatively overactive ventral striatal (VS) motivational circuit that readily energizes approach toward salient appetitive cues. However, other evidence fosters a theory that this circuit is developmentally underactive, in which adolescents approach more robust incentives (such as risk taking or drug experimentation) to recruit this circuitry. To help resolve this, we compared brain activation in 12 adolescents (12-17 years of age) and 12 young adults (22-28 years of age) while they anticipated the opportunity to respond to obtain monetary gains as well as to avoid monetary losses. In both age groups, anticipation of potential gain activated portions of the VS, right insula, dorsal thalamus, and dorsal midbrain, where the magnitude of VS activation was sensitive to gain amount. Notification of gain outcomes (in contrast with missed gains) activated the mesial frontal cortex (mFC). Across all subjects, signal increase in the right nucleus accumbens during anticipation of responding for large gains independently correlated with both age and self-rated excitement about the high gain cue. In direct comparison, adolescents evidenced less recruitment of the right VS and right-extended amygdala while anticipating responding for gains (in contrast with anticipation of nongains) compared with young adults. However, brain activation after gain outcomes did not appreciably differ between age groups. These results suggest that adolescents selectively show reduced recruitment of motivational but not consummatory components of reward-directed behavior." @default.
- W2097716692 created "2016-06-24" @default.
- W2097716692 creator A5001061769 @default.
- W2097716692 creator A5004037731 @default.
- W2097716692 creator A5035277168 @default.
- W2097716692 creator A5050193368 @default.
- W2097716692 creator A5052014576 @default.
- W2097716692 creator A5070667618 @default.
- W2097716692 date "2004-02-25" @default.
- W2097716692 modified "2023-10-04" @default.
- W2097716692 title "Incentive-Elicited Brain Activation in Adolescents: Similarities and Differences from Young Adults" @default.
- W2097716692 cites W1599955462 @default.
- W2097716692 cites W1967922673 @default.
- W2097716692 cites W1973466311 @default.
- W2097716692 cites W1977370225 @default.
- W2097716692 cites W1978453350 @default.
- W2097716692 cites W1980654400 @default.
- W2097716692 cites W1981765923 @default.
- W2097716692 cites W1985052963 @default.
- W2097716692 cites W1985645068 @default.
- W2097716692 cites W1988965958 @default.
- W2097716692 cites W1992467985 @default.
- W2097716692 cites W1993631201 @default.
- W2097716692 cites W2001458321 @default.
- W2097716692 cites W2006557707 @default.
- W2097716692 cites W2006734443 @default.
- W2097716692 cites W2029049055 @default.
- W2097716692 cites W2033762218 @default.
- W2097716692 cites W2034398954 @default.
- W2097716692 cites W2034744639 @default.
- W2097716692 cites W2043626485 @default.
- W2097716692 cites W2044359951 @default.
- W2097716692 cites W2051285353 @default.
- W2097716692 cites W2051691068 @default.
- W2097716692 cites W2055018246 @default.
- W2097716692 cites W2080839667 @default.
- W2097716692 cites W2082117755 @default.
- W2097716692 cites W2087983777 @default.
- W2097716692 cites W2088763095 @default.
- W2097716692 cites W2102773298 @default.
- W2097716692 cites W2103145224 @default.
- W2097716692 cites W2106261260 @default.
- W2097716692 cites W2117140276 @default.
- W2097716692 cites W2117649346 @default.
- W2097716692 cites W2119128116 @default.
- W2097716692 cites W2127877407 @default.
- W2097716692 cites W2130526861 @default.
- W2097716692 cites W2140142910 @default.
- W2097716692 cites W2151811639 @default.
- W2097716692 cites W2151837102 @default.
- W2097716692 cites W2152292563 @default.
- W2097716692 cites W2156777444 @default.
- W2097716692 cites W2157088567 @default.
- W2097716692 cites W2158972787 @default.
- W2097716692 cites W2164700628 @default.
- W2097716692 cites W2166866921 @default.
- W2097716692 doi "https://doi.org/10.1523/jneurosci.4862-03.2004" @default.
- W2097716692 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6730402" @default.
- W2097716692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14985419" @default.
- W2097716692 hasPublicationYear "2004" @default.
- W2097716692 type Work @default.
- W2097716692 sameAs 2097716692 @default.
- W2097716692 citedByCount "516" @default.
- W2097716692 countsByYear W20977166922012 @default.
- W2097716692 countsByYear W20977166922013 @default.
- W2097716692 countsByYear W20977166922014 @default.
- W2097716692 countsByYear W20977166922015 @default.
- W2097716692 countsByYear W20977166922016 @default.
- W2097716692 countsByYear W20977166922017 @default.
- W2097716692 countsByYear W20977166922018 @default.
- W2097716692 countsByYear W20977166922019 @default.
- W2097716692 countsByYear W20977166922020 @default.
- W2097716692 countsByYear W20977166922021 @default.
- W2097716692 countsByYear W20977166922022 @default.
- W2097716692 countsByYear W20977166922023 @default.
- W2097716692 crossrefType "journal-article" @default.
- W2097716692 hasAuthorship W2097716692A5001061769 @default.
- W2097716692 hasAuthorship W2097716692A5004037731 @default.
- W2097716692 hasAuthorship W2097716692A5035277168 @default.
- W2097716692 hasAuthorship W2097716692A5050193368 @default.
- W2097716692 hasAuthorship W2097716692A5052014576 @default.
- W2097716692 hasAuthorship W2097716692A5070667618 @default.
- W2097716692 hasBestOaLocation W20977166921 @default.
- W2097716692 hasConcept C104996578 @default.
- W2097716692 hasConcept C138496976 @default.
- W2097716692 hasConcept C154945302 @default.
- W2097716692 hasConcept C15744967 @default.
- W2097716692 hasConcept C169760540 @default.
- W2097716692 hasConcept C176777502 @default.
- W2097716692 hasConcept C205545832 @default.
- W2097716692 hasConcept C2776552330 @default.
- W2097716692 hasConcept C2779144063 @default.
- W2097716692 hasConcept C41008148 @default.
- W2097716692 hasConcept C529278444 @default.
- W2097716692 hasConcept C552161191 @default.
- W2097716692 hasConceptScore W2097716692C104996578 @default.
- W2097716692 hasConceptScore W2097716692C138496976 @default.
- W2097716692 hasConceptScore W2097716692C154945302 @default.