Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097757572> ?p ?o ?g. }
- W2097757572 endingPage "4147" @default.
- W2097757572 startingPage "4135" @default.
- W2097757572 abstract "Mutations of the glycoprotein rBAT cause cystinuria type I, an autosomal recessive failure of dibasic amino acid transport (b(0,+) type) across luminal membranes of intestine and kidney cells. Here we identify the permease-like protein b(0,+)AT as the catalytic subunit that associates by a disulfide bond with rBAT to form a hetero-oligomeric b(0,+) amino acid transporter complex. We demonstrate its b(0,+)-type amino acid transport kinetics using a heterodimeric fusion construct and show its luminal brush border localization in kidney proximal tubule. These biochemical, transport, and localization characteristics as well as the chromosomal localization on 19q support the notion that the b(0,+)AT protein is the product of the gene defective in non-type I cystinuria." @default.
- W2097757572 created "2016-06-24" @default.
- W2097757572 creator A5003847730 @default.
- W2097757572 creator A5004008130 @default.
- W2097757572 creator A5008957622 @default.
- W2097757572 creator A5015311189 @default.
- W2097757572 creator A5020891892 @default.
- W2097757572 creator A5022079984 @default.
- W2097757572 creator A5031639542 @default.
- W2097757572 creator A5060806960 @default.
- W2097757572 creator A5071507929 @default.
- W2097757572 date "1999-12-01" @default.
- W2097757572 modified "2023-10-10" @default.
- W2097757572 title "Luminal Heterodimeric Amino Acid Transporter Defective in Cystinuria" @default.
- W2097757572 cites W1495130493 @default.
- W2097757572 cites W1525006850 @default.
- W2097757572 cites W1540095279 @default.
- W2097757572 cites W1555349795 @default.
- W2097757572 cites W1563271921 @default.
- W2097757572 cites W1566671445 @default.
- W2097757572 cites W1569463778 @default.
- W2097757572 cites W1601032788 @default.
- W2097757572 cites W1606091578 @default.
- W2097757572 cites W1613701641 @default.
- W2097757572 cites W1849889294 @default.
- W2097757572 cites W1969339813 @default.
- W2097757572 cites W1971095258 @default.
- W2097757572 cites W1976678735 @default.
- W2097757572 cites W1982958681 @default.
- W2097757572 cites W1986125198 @default.
- W2097757572 cites W1991054305 @default.
- W2097757572 cites W1993845081 @default.
- W2097757572 cites W2008040920 @default.
- W2097757572 cites W2010276700 @default.
- W2097757572 cites W2011223596 @default.
- W2097757572 cites W2020798806 @default.
- W2097757572 cites W2023790531 @default.
- W2097757572 cites W2026914265 @default.
- W2097757572 cites W2028206171 @default.
- W2097757572 cites W2028414806 @default.
- W2097757572 cites W2037604964 @default.
- W2097757572 cites W2046507378 @default.
- W2097757572 cites W2065406627 @default.
- W2097757572 cites W2072620493 @default.
- W2097757572 cites W2086562923 @default.
- W2097757572 cites W2088839227 @default.
- W2097757572 cites W2131375511 @default.
- W2097757572 cites W2133645165 @default.
- W2097757572 cites W2145806440 @default.
- W2097757572 cites W2147385203 @default.
- W2097757572 cites W2159806870 @default.
- W2097757572 cites W2172196142 @default.
- W2097757572 cites W2329394811 @default.
- W2097757572 cites W2342978219 @default.
- W2097757572 cites W2408221665 @default.
- W2097757572 cites W4298064649 @default.
- W2097757572 doi "https://doi.org/10.1091/mbc.10.12.4135" @default.
- W2097757572 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/25748" @default.
- W2097757572 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10588648" @default.
- W2097757572 hasPublicationYear "1999" @default.
- W2097757572 type Work @default.
- W2097757572 sameAs 2097757572 @default.
- W2097757572 citedByCount "122" @default.
- W2097757572 countsByYear W20977575722013 @default.
- W2097757572 countsByYear W20977575722014 @default.
- W2097757572 countsByYear W20977575722015 @default.
- W2097757572 countsByYear W20977575722016 @default.
- W2097757572 countsByYear W20977575722017 @default.
- W2097757572 countsByYear W20977575722018 @default.
- W2097757572 countsByYear W20977575722019 @default.
- W2097757572 countsByYear W20977575722020 @default.
- W2097757572 countsByYear W20977575722021 @default.
- W2097757572 countsByYear W20977575722022 @default.
- W2097757572 countsByYear W20977575722023 @default.
- W2097757572 crossrefType "journal-article" @default.
- W2097757572 hasAuthorship W2097757572A5003847730 @default.
- W2097757572 hasAuthorship W2097757572A5004008130 @default.
- W2097757572 hasAuthorship W2097757572A5008957622 @default.
- W2097757572 hasAuthorship W2097757572A5015311189 @default.
- W2097757572 hasAuthorship W2097757572A5020891892 @default.
- W2097757572 hasAuthorship W2097757572A5022079984 @default.
- W2097757572 hasAuthorship W2097757572A5031639542 @default.
- W2097757572 hasAuthorship W2097757572A5060806960 @default.
- W2097757572 hasAuthorship W2097757572A5071507929 @default.
- W2097757572 hasBestOaLocation W20977575722 @default.
- W2097757572 hasConcept C104292427 @default.
- W2097757572 hasConcept C104317684 @default.
- W2097757572 hasConcept C149011108 @default.
- W2097757572 hasConcept C153911025 @default.
- W2097757572 hasConcept C181199279 @default.
- W2097757572 hasConcept C2776608514 @default.
- W2097757572 hasConcept C2777608289 @default.
- W2097757572 hasConcept C2779201268 @default.
- W2097757572 hasConcept C2779950389 @default.
- W2097757572 hasConcept C2781313199 @default.
- W2097757572 hasConcept C515207424 @default.
- W2097757572 hasConcept C55493867 @default.
- W2097757572 hasConcept C57581600 @default.