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- W2097807810 abstract "Our objective was to assess the feasibility of <sup>18</sup>F-FDG PET/CT for noninvasive monitoring of treatment response after allogeneic stem cell transplantation (SCT) for myelofibrosis. <b>Methods:</b> Twelve patients with myelofibrosis underwent <sup>18</sup>F-FDG PET/CT before and after SCT. Bone marrow uptake, spleen uptake, and spleen size were assessed before and after SCT and compared with hematologic response criteria and bone marrow biopsies. <b>Results:</b> All patients who did not achieve complete remission remained PET-positive (<i>P</i> = 0.02). Extent of disease, bone marrow metabolism, spleen metabolism, and spleen volume decreased significantly in patients with complete remission (<i>P</i> = 0.03). PET/CT after SCT had a sensitivity of 1.0 (95% confidence interval [CI], 0.54–1.0), a specificity of 0.83 (95% CI, 0.36–1.0), a negative predictive value of 1.0 (95% CI, 0.48–1.0), and a positive predictive value of 0.86 (95% CI, 0.42–1.0) for diagnosis of residual disease. <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT is feasible for noninvasive monitoring of treatment response after allogeneic SCT for myelofibrosis." @default.
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- W2097807810 title "Factors determining maximum inspiratory flow and maximum expiratory flow of the lung" @default.
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- W2097807810 doi "https://doi.org/10.1136/thx.23.1.33" @default.
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