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- W2097830631 abstract "textabstractAlthough a large therapeutic arsenal of conventional drugs is available to treat patientswith psoriasis, a group of patients still exists that fulfill the inherent exclusion criteria orpresent with subjective or objective side-effects. This necessitates the need for controlledstudies with potential new antipsoriatic drugs like cyclosporin A. In this thesis patientorientedstudies on the treatment of severe psoriasis vulgaris with systemic low-dose andtopical cyclosporin A are presented in an attempt to answer the following questions.A - What is the efficacy of short-term low-dose cyclosporin A in patients with severe,recalcitrant psoriasis ? (Chapters 3 and 4)B - Is there a preferential dose regimen for long-term treatment, either continous orintermittent ? Can the combination with a conventional drug like etretinate produce an additive positive effect ? (Chapter 5)C- Can topically applied cyclosporin A be effective in dermatologic disorders such aspsoriasis ? (Chapter 6)D - What are the side-effects of orally administered cyclosporin A ? How can nephrotoxocitybe monitored ? What are the recommended guidelines for the practicingdermatologist for using cyclosporin A ? (Chapters 7 and 8)" @default.
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- W2097830631 date "1991-06-26" @default.
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- W2097830631 title "Cyclosporin A in psoriasis" @default.
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