Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097848632> ?p ?o ?g. }
- W2097848632 endingPage "264" @default.
- W2097848632 startingPage "259" @default.
- W2097848632 abstract "Breast cancer is an important public health problem worldwide and it represents the second leading cause of cancer-related deaths among women in most industrialized countries. Epidemiological studies suggest a much lower incidence of breast cancer in women from countries with high soy phytoestrogen consumption such as China and Japan than the Western world. Phytoestrogens are a group of plant-derived polyphenol compounds that exhibit structural and functional similarities to the human steroid hormone 17β-estradiol. Genistein and daidzein, the main soy phytoestrogens, are two estrogen-mimicking compounds which can bind to estrogen receptors and exert weak estrogenic effects. There are several possible mechanisms by which these phytochemicals may reduce the risk of breast cancer; however their precise mechanisms of action remain to be elucidated. This review will summarize the properties of genistein and daidzein as phytoestrogens, and their chemopreventive effects in breast carcinogenesis including their antioxidant properties, antiinflammatory activities as well as their antiprogression abilities, and their importance in xenobiotic metabolism. Because the use of soy phytoestrogens is increasing, it is important from a public health perspective and a mechanistic understanding to study the potential links existing between soy phytoestrogens and breast cancer prevention. Keywords: Breast cancer, chemoprevention, phytoestrogen, isoflavone, genistein, daidzein" @default.
- W2097848632 created "2016-06-24" @default.
- W2097848632 creator A5004117957 @default.
- W2097848632 creator A5017278566 @default.
- W2097848632 creator A5046205789 @default.
- W2097848632 creator A5070768873 @default.
- W2097848632 date "2008-11-01" @default.
- W2097848632 modified "2023-10-18" @default.
- W2097848632 title "Soy Phytoestrogens and Breast Cancer Chemoprevention: Molecular Mechanisms" @default.
- W2097848632 cites W1500074116 @default.
- W2097848632 cites W1605046409 @default.
- W2097848632 cites W1673057815 @default.
- W2097848632 cites W1858959628 @default.
- W2097848632 cites W1876611656 @default.
- W2097848632 cites W1897822125 @default.
- W2097848632 cites W1933411778 @default.
- W2097848632 cites W1939905704 @default.
- W2097848632 cites W1964139069 @default.
- W2097848632 cites W1969165223 @default.
- W2097848632 cites W1972642439 @default.
- W2097848632 cites W1999002791 @default.
- W2097848632 cites W2002673092 @default.
- W2097848632 cites W2008116867 @default.
- W2097848632 cites W2010547780 @default.
- W2097848632 cites W2014676294 @default.
- W2097848632 cites W2020115882 @default.
- W2097848632 cites W2022895967 @default.
- W2097848632 cites W2025233617 @default.
- W2097848632 cites W2031456594 @default.
- W2097848632 cites W2032303692 @default.
- W2097848632 cites W2034328958 @default.
- W2097848632 cites W2035059539 @default.
- W2097848632 cites W2037250108 @default.
- W2097848632 cites W2039977710 @default.
- W2097848632 cites W2044715732 @default.
- W2097848632 cites W2047849846 @default.
- W2097848632 cites W2049970571 @default.
- W2097848632 cites W2051813834 @default.
- W2097848632 cites W2055524082 @default.
- W2097848632 cites W2056398994 @default.
- W2097848632 cites W2057705659 @default.
- W2097848632 cites W2066721336 @default.
- W2097848632 cites W2066870405 @default.
- W2097848632 cites W2067918250 @default.
- W2097848632 cites W2072383429 @default.
- W2097848632 cites W2072950367 @default.
- W2097848632 cites W2075654456 @default.
- W2097848632 cites W2081982294 @default.
- W2097848632 cites W2082942776 @default.
- W2097848632 cites W2088524561 @default.
- W2097848632 cites W2089775638 @default.
- W2097848632 cites W2092597427 @default.
- W2097848632 cites W2098602939 @default.
- W2097848632 cites W2098640833 @default.
- W2097848632 cites W2106199905 @default.
- W2097848632 cites W2108319912 @default.
- W2097848632 cites W2109731526 @default.
- W2097848632 cites W2111159443 @default.
- W2097848632 cites W2116680419 @default.
- W2097848632 cites W2123925631 @default.
- W2097848632 cites W2129075998 @default.
- W2097848632 cites W2131145936 @default.
- W2097848632 cites W2132069091 @default.
- W2097848632 cites W2132921162 @default.
- W2097848632 cites W2136636869 @default.
- W2097848632 cites W2136848797 @default.
- W2097848632 cites W2137672355 @default.
- W2097848632 cites W2143567248 @default.
- W2097848632 cites W2145657145 @default.
- W2097848632 cites W2147378653 @default.
- W2097848632 cites W2150589843 @default.
- W2097848632 cites W2152025445 @default.
- W2097848632 cites W2156460034 @default.
- W2097848632 cites W2166766053 @default.
- W2097848632 cites W2167550154 @default.
- W2097848632 cites W2169238639 @default.
- W2097848632 cites W2169790062 @default.
- W2097848632 cites W2171451883 @default.
- W2097848632 cites W2412930066 @default.
- W2097848632 cites W79700415 @default.
- W2097848632 doi "https://doi.org/10.2174/157340108786263658" @default.
- W2097848632 hasPublicationYear "2008" @default.
- W2097848632 type Work @default.
- W2097848632 sameAs 2097848632 @default.
- W2097848632 citedByCount "7" @default.
- W2097848632 countsByYear W20978486322012 @default.
- W2097848632 countsByYear W20978486322013 @default.
- W2097848632 countsByYear W20978486322018 @default.
- W2097848632 crossrefType "journal-article" @default.
- W2097848632 hasAuthorship W2097848632A5004117957 @default.
- W2097848632 hasAuthorship W2097848632A5017278566 @default.
- W2097848632 hasAuthorship W2097848632A5046205789 @default.
- W2097848632 hasAuthorship W2097848632A5070768873 @default.
- W2097848632 hasConcept C121608353 @default.
- W2097848632 hasConcept C126322002 @default.
- W2097848632 hasConcept C134018914 @default.
- W2097848632 hasConcept C2777164284 @default.
- W2097848632 hasConcept C2778270713 @default.