FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097858321> ?p ?o ?g. }

• W2097858321 endingPage "559" @default.
• W2097858321 startingPage "551" @default.
• W2097858321 abstract "ABSTRACT The extracts and pure major constituents of Chios mastic gum (resin of Pistacia lentiscus var. chia ) were tested for their activities against Helicobacter pylori . A total mastic extract without polymer (TMEWP) was prepared after removal of the contained insoluble polymer in order to ameliorate solubility and enhance in vivo activity. Administration of TMEWP to H. pylori SS1-infected mice over the period of 3 months with an average dose of 0.75 mg/day led to an approximately 30-fold reduction in the H. pylori colonization (1.5 log CFU/g of tissue). However, no attenuation in the H. pylori -associated chronic inflammatory infiltration and the activity of chronic gastritis was observed. To further characterize potential active mastic constituents, the TMEWP was separated into an acidic and a neutral fraction. Both were extensively characterized by nuclear magnetic resonance and mass spectroscopy to elucidate the structure of the components contained within each fraction. After chromatographic separation, the acid fraction gave the major triterpenic acids, while the neutral fraction gave several triterpenic alcohols and aldehydes. Mastic extracts and isolated pure triterpenic acids were tested for in vitro activity against a panel of 11 H. pylori clinical strains. The acid fraction was found to be the most active extract (minimum bactericidal concentration [MBC], 0.139 mg/ml), and the most active pure compound was isomasticadienolic acid (MBC, 0.202 mg/ml [0.443 mM]). Our results show that administration of TMEWP may be effective in reducing H. pylori colonization and that the major triterpenic acids in the acid extract may be responsible for such an activity." @default.
• W2097858321 created "2016-06-24" @default.
• W2097858321 creator A5003191912 @default.
• W2097858321 creator A5004170077 @default.
• W2097858321 creator A5004621425 @default.
• W2097858321 creator A5012514928 @default.
• W2097858321 creator A5017277832 @default.
• W2097858321 creator A5042462717 @default.
• W2097858321 creator A5042908077 @default.
• W2097858321 creator A5059685093 @default.
• W2097858321 creator A5089793216 @default.
• W2097858321 date "2007-02-01" @default.
• W2097858321 modified "2023-10-17" @default.
• W2097858321 title "In Vitro and In Vivo Activities of Chios Mastic Gum Extracts and Constituents against <i>Helicobacter pylori</i>" @default.
• W2097858321 cites W1862122604 @default.
• W2097858321 cites W1967237783 @default.
• W2097858321 cites W1993310293 @default.
• W2097858321 cites W1994523318 @default.
• W2097858321 cites W1999447480 @default.
• W2097858321 cites W1999587546 @default.
• W2097858321 cites W2005954436 @default.
• W2097858321 cites W2007579282 @default.
• W2097858321 cites W2022417559 @default.
• W2097858321 cites W2022841972 @default.
• W2097858321 cites W2029851838 @default.
• W2097858321 cites W2030512570 @default.
• W2097858321 cites W2035490422 @default.
• W2097858321 cites W2038472202 @default.
• W2097858321 cites W2062197943 @default.
• W2097858321 cites W2077789212 @default.
• W2097858321 cites W2086146132 @default.
• W2097858321 cites W2095735547 @default.
• W2097858321 cites W2107637566 @default.
• W2097858321 cites W2116432399 @default.
• W2097858321 cites W2122178491 @default.
• W2097858321 cites W2147519235 @default.
• W2097858321 cites W2151466973 @default.
• W2097858321 cites W2151849478 @default.
• W2097858321 cites W2154731763 @default.
• W2097858321 cites W2159740312 @default.
• W2097858321 cites W2162479824 @default.
• W2097858321 cites W2164929597 @default.
• W2097858321 cites W2165551941 @default.
• W2097858321 cites W2315321109 @default.
• W2097858321 cites W2948387191 @default.
• W2097858321 doi "https://doi.org/10.1128/aac.00642-06" @default.
• W2097858321 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1797732" @default.
• W2097858321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17116667" @default.
• W2097858321 hasPublicationYear "2007" @default.
• W2097858321 type Work @default.
• W2097858321 sameAs 2097858321 @default.
• W2097858321 citedByCount "147" @default.
• W2097858321 countsByYear W20978583212012 @default.
• W2097858321 countsByYear W20978583212013 @default.
• W2097858321 countsByYear W20978583212014 @default.
• W2097858321 countsByYear W20978583212015 @default.
• W2097858321 countsByYear W20978583212016 @default.
• W2097858321 countsByYear W20978583212017 @default.
• W2097858321 countsByYear W20978583212018 @default.
• W2097858321 countsByYear W20978583212019 @default.
• W2097858321 countsByYear W20978583212020 @default.
• W2097858321 countsByYear W20978583212021 @default.
• W2097858321 countsByYear W20978583212022 @default.
• W2097858321 countsByYear W20978583212023 @default.
• W2097858321 crossrefType "journal-article" @default.
• W2097858321 hasAuthorship W2097858321A5003191912 @default.
• W2097858321 hasAuthorship W2097858321A5004170077 @default.
• W2097858321 hasAuthorship W2097858321A5004621425 @default.
• W2097858321 hasAuthorship W2097858321A5012514928 @default.
• W2097858321 hasAuthorship W2097858321A5017277832 @default.
• W2097858321 hasAuthorship W2097858321A5042462717 @default.
• W2097858321 hasAuthorship W2097858321A5042908077 @default.
• W2097858321 hasAuthorship W2097858321A5059685093 @default.
• W2097858321 hasAuthorship W2097858321A5089793216 @default.
• W2097858321 hasBestOaLocation W20978583211 @default.
• W2097858321 hasConcept C150903083 @default.
• W2097858321 hasConcept C176947019 @default.
• W2097858321 hasConcept C185592680 @default.
• W2097858321 hasConcept C18903297 @default.
• W2097858321 hasConcept C202751555 @default.
• W2097858321 hasConcept C207001950 @default.
• W2097858321 hasConcept C26381139 @default.
• W2097858321 hasConcept C2776409635 @default.
• W2097858321 hasConcept C2776673659 @default.
• W2097858321 hasConcept C2779703632 @default.
• W2097858321 hasConcept C2780034687 @default.
• W2097858321 hasConcept C2780037293 @default.
• W2097858321 hasConcept C43617362 @default.
• W2097858321 hasConcept C4646841 @default.
• W2097858321 hasConcept C54355233 @default.
• W2097858321 hasConcept C55493867 @default.
• W2097858321 hasConcept C556039675 @default.
• W2097858321 hasConcept C59822182 @default.
• W2097858321 hasConcept C71924100 @default.
• W2097858321 hasConcept C86803240 @default.
• W2097858321 hasConcept C98274493 @default.
• W2097858321 hasConceptScore W2097858321C150903083 @default.
• W2097858321 hasConceptScore W2097858321C176947019 @default.

• next